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Doctor insights on: Chronic Neutrophilic Leukemia

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How is acute myeloid leukemia different from chronic lymphoma leukemia?

How is acute myeloid leukemia different from chronic lymphoma leukemia?

Different cell type: Leukemias typically originate when one of the white blood cell types starts multiplying out of control and preventing the normal cells from doing their job. There are many types of white blood cells and the subtype of leukemia or lymphoma or myeloma depends on which subtype is out of control. ...Read more

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Dr. Liawaty Ho
1,144 doctors shared insights

Leukemia (Definition)

A malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more


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What is chronic myeloid leukemia?

What is chronic myeloid leukemia?

Marrow cancer: CML is a marrow malignancy characterized by excessive number of white blood cells with various degrees of maturation. Most CML patients have deficient number of red cells and platelets. CML responds dramatically to oral agents called tyrosine kinase inhibitors. Examples are Gleevec and Sprycel (dasatinib). ...Read more

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What is chronic myelogenous leukemia?

What is chronic myelogenous leukemia?

A blood cancer: CML is a blood cancer that develops slowly (hence chronic). If untreated it will eventually be life threatening. It is associated a unique chromosomal injury, the philadelphia chromosome. New drugs (tkis) target this damage and reliably produce remissions in early stage patients that often are long lasting. ...Read more

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What's acute myeloid leukemia?

What's acute myeloid leukemia?

Blood cancer: AML is a blood cancer affecting a type of white blood cells called myeloid cells. It often occurs in late adult/elderly patients and has a short development phase usually (hence acute). Intensive chemotherapy and often bone marrow transplant can be effective with long term survival in 40-50% cases. AML in the elderly is more difficult to treat and results are worse. ...Read more

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Dangers of chronic myelogenous leukemia?

Can be fatal: This is a disease that was associated with a shortened life span. The discovery of a specific cancer cell mutation and medications that attack that mutation have dramatically affected the outcome. This is now a disease that people can live for many years and be functional and productive. ...Read more

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Aml acute myeloid leukemia is what?

Aml acute myeloid leukemia is what?

AML is a cancer.....: Of the bone marrow (actually a group of cancers) whose precise causes are unknown, but about which we know considerable molecular detail and are learning more each day. The disease arises from the hematopoietic stem/progenitor cells in the bone marrow when these cells acquire mutations that allow them to escape controls on growth and apoptosis. Subtype info is found on the nci website. ...Read more

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What is chronic myelogenous leukemia (cml)?

What is chronic myelogenous leukemia (cml)?

White cell cancer: The bone marrow cells that produce granulocytes (needed to fight infections) grow out of control and are present in large numbers in the blood and other organs. The disease is quite treatable these days because of targeted therapy and long lasting remissions are possible in most people. ...Read more

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What causes acute myelogenous leukemia?

What causes acute myelogenous leukemia?

DNA mutations: Leukemias occur due to mutations in dna. Many mutations have been linked to aml, however, the cause for most of the mutations remains unclear. Known risks include radiation exposure and certain chemical exposure. ...Read more

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Define differential diagnosis of prolymphocytic leukemia or mantle cell leukemia.

Define differential diagnosis of prolymphocytic leukemia or mantle cell leukemia.

They are too differe: There should be no confusion between these two entities. One is a lymphoma(nodal disease) the other one is a blood cancer that should not affect the lymph nodes. Rather easy diagnosis if you are seeing the right type of specialist! ...Read more

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Chronic sinusitis and chronic lymphocytic leukemia--not good together?

Low IgG?: agreed. Frequent bacterial infection associated with CLL may be due to hypogammaglobulinemia (Low amount of antibodies, also called low IgG). That's treatable with monthly infusion of IVIG (intravenous immune globulin). Discuss with hematologist/oncologist. ...Read more

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Is acute myeloid leukemia harmful?

Is acute myeloid leukemia harmful?

Yes! AML can kill.: Acute myeloid leukemia can be very aggressive. Generally it is treated at major clinical centers with a lot of expertise in leukemia especially at first. AML is seen in both children and adults. I would recommend that if either you or a family member is diagnosed with this to seek out a center of excellence. ...Read more

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Is likely that chronic lymphocytic leukemia (cll) live?

Is likely that chronic lymphocytic leukemia (cll) live?

Yes: Many CLL patient's live a long and productive life. Having said that it is a leukemia , it will eventually need therapy. ...Read more

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Is chronic pancytopenia anemia curable?

Is chronic pancytopenia anemia curable?

Depends on cause: Chronic pancytopenia means low white & red cells and low platelets. Reversible causes such as nutritional deficinecies, immune disorders, drug-related can be treated effectively. However, patientsw with inherited conditions or bone marrow disorders need a detailed work-up and treatments may not be effective. ...Read more

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What percent of leukemias does acute myeloid leukemia represent?

AML: AML is the most common acute leukemia in adults and accounts for approximately 80 % of cases in this group. In us and europe, the incidence has been stable at 3 to 5 cases per 100, 000 population. In contrast, AML accounts for less than 10 % of acute leukemias in children less than 10 years of age. ...Read more

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How can chronic myelogenous leukemia cause hepatomegaly?

Infiltration: The speen does enlarge in this disease. The causes include direct inflitration. Another is production of other blood elements (extramedullary hematopoesis) in the speen in response to either replacement of the marrow with CML or scar. The scarring is called myelofibrosis. ...Read more

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Chronic lymphoblastic leukemia (cll) is cll terminal? Is there a cure?

Chronic lymphoblastic leukemia (cll) is cll terminal? Is there a cure?

See below...: Chronic lymphoblastic leukemia does not exist. Cll stands for chronic lymphocytic leukemia. Lymphoblastic leukemias are acute.The only known complete cure for cll is stem cell transplantation; however, many patients do not need any form of therapy unless there are symptoms or adverse prognostic factors. Cll is usually not an aggressive form of leukemia and has a relatively good prognosis overall. ...Read more

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What sort of disease is chronic myelogenous leukemia (c.M.L.)?

Bcr-abl: CML is a clonal disorder (cancer) of the white blood cells in the blood (= -emia part). Other leukemias include cll, aml, all, etc. CML is often diagnosed by testing on peripheral blood or bone marrow. The bcr-abl translocation (philadelphia chromosome) is found in cml. Treatment may be a variety of pills. The most common initial treatment has been gleevec (imatinib). Other drugs are available. ...Read more

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What sort of disease is chronic lymphocytic leukemia (c.L.L.)?

What sort of disease is chronic lymphocytic leukemia (c.L.L.)?

CLL: Cll is a clonal disorder (cancer) of the white blood cells (specifically lymphocytes) in the blood (= -emia part). Other leukemias include cml, aml, all, etc. Cll is often diagnosed by flow cytometry on peripheral blood. Additional studies may include ct scans and bone marrow biopsy. One staging system is rai 0 to iv. Treatment ranges from observation (rai 0-1) to various tx individualized to pt. ...Read more

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