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Doctor insights on: Chronic Myeloid Leukamia

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What is chronic myeloid leukemia?

What is chronic myeloid leukemia?

Marrow cancer: CML is a marrow malignancy characterized by excessive number of white blood cells with various degrees of maturation. Most CML patients have deficient number of red cells and platelets. CML responds dramatically to oral agents called tyrosine kinase inhibitors. Examples are Gleevec and Sprycel (dasatinib). ...Read more

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What are some treatments for chronic myeloid lukemia?

What are some treatments for chronic myeloid lukemia?

See below...: First of all, the treatment for any type of leukemia should be coordinated by a hematologist/oncologist. To answer your question, chemotherapy is usually necessary like for any other type of leukemia; however, there is also a special drug that is central in the chronic treatment of cml, namely Gleevec (imatinib), with a specific benefit in this type of leukemia. ...Read more

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Which systems are affected by chronic myeloid leukemia?

Which systems are affected by chronic myeloid leukemia?

Primarily the blood: While it is a cancer of the white blood cells, if it is not well controlled, then CML can affect the whole body by affecting your immune system and blood supply. ...Read more

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Can you die from chronic myeloid leukemia if it is only in it's first stages?

Can you die from chronic myeloid leukemia if it is only in it's first stages?

Possible but unlikel: There have been excellent therapies for this disease with Gleevec (imatinib) and newer drugs. The data is suggesting that for many patients their survival can be close to the normal population. The drugs make the disease behave. There are a small percentage who do not respond well. Your doctor can give you precise info on your situation and how you will know that you are responding well to treatment. ...Read more

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What is there to expect in the last stage of leukemia, chronic myeloid leukemia?

What is there to expect in the last stage of leukemia, chronic myeloid leukemia?

The last: Stage of CML is known as "blast crisis." it behaves like a treatment refractory acute myeloid leukemia. The typical survival is weeks to a few months. ...Read more

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Why there is increase in transcobalamin ||| in chronic myeloid leukemia ?

Nobody knows: This will be abundantly clear to you after you read the last major review from Oxford, 2013. They simply gloss over the "why". http://qjmed.oxfordjournals.org/content/early/2013/02/27/qjmed.hct051 ...Read more

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What is the life expectancy for a 20 year old with chronic myeloid leukaemia?

Maybe normal.: If the CML is diagnosed in early chronic phase, if it responds to treatment with a complete molecular response, long term survival is excellent. We only have 10 year or so information for the new drugs used in cml, but for those patients who are out 10 years, we think their survival may be unaffected by the leukemia. That is why bone marrow transplant is no longer the initial treatment for cml. ...Read more

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I need to know if there is a cure for chronic myeloid leukemia (cml)?

Yes : CML used to be bad, 50% dead in 5 years. Today treatment with tyrosine kinase inhibitors results in 95% of patients being alive 5 years after diagnosis. So far, treatment with tkis does not seem to permanently eliminate the leukemia, requiring continued rx. A smaller proportion of patients who fail tki rx can get transplants and be truly cured, but at the risk of complications. See a good hem/onc! ...Read more

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How is acute myeloid leukemia different from chronic lymphoma leukemia?

Different cell type: Leukemias typically originate when one of the white blood cell types starts multiplying out of control and preventing the normal cells from doing their job. There are many types of white blood cells and the subtype of leukemia or lymphoma or myeloma depends on which subtype is out of control. ...Read more

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