Top
30
Doctor insights on: Chronic Microvascular White Matter Ischemic Changes

Share

White Matter (Definition)

White matter is one of the two components of the central nervous system and consists of glial cells and myelinated axons that transmit signals from one region of the cerebrum to another and between the cerebrum and lower brain centers. White matter tissue of the freshly cut brain appears pinkish white to the naked eye because myelin is composed largely of lipid ...Read more


2

2
What is chronic periventricular white matter microvascular ischemic disease?

What is chronic periventricular white matter microvascular ischemic disease?

Patchy insulation: Chronic means this process has been going on for years in the brain. White matter is the part of the brain where the "communication cables" are, and they are "white" because of myelin insulation. The ventricles are fluid-filled "shock absorber" spaces inside the brain. Ischemic means they have been deprived oxygen, microvascular means in tiny blood vessels. Mini-stroke strips off some insulation. ...Read more

3

3
My MRI shows "MILD WHITE MATTER MICROVASCULAR ISCHEMIC CHANGES". Could this be a reason for my memory issues and word-finding issues?

My MRI shows "MILD WHITE MATTER MICROVASCULAR ISCHEMIC CHANGES". Could this be a reason for my memory issues and word-finding issues?

Vascular dementia.: The second most common form of dementia (after Alzheimer's) is vascular dementia, also known as multi-infarct dementia. An accumulation of tiny infarcts, much like those imaged on your MRI, leads to symptoms of dementia. We tend to see this form of dementia in people with hypertension, diabetes, high cholesterol. So this could be related to your symptoms. Ask your doctor if u can take aspirin. ...Read more

6

6
Is it normal for a 42 yr old female to have chronic microvascular ischemic changes of the brain & what could be the cause? History chronic muscle pn

Is it normal for a 42 yr old female to have chronic microvascular ischemic changes of the brain & what could be the cause? History chronic muscle pn

Brain: My opinion on chronic microvascular changes... Most important is how bad. Sometimes there are a few small speckles seen in people with migraines that are definitely not worrisome. Otherwise, risk factors for this are: smoking, high bp/cholesterol, diabetes, drug use, and genetics... Among other rare causes. My biggest recs would be to work on any changeable things like some of these. ...Read more

7

7
Hello dr, I had an MRI of my brain. It came back as slight chronic microvascular ischemic changes. What does that mean? Also, what does an air cell mean?

Hello dr, I had an MRI of my brain. It came back as slight chronic microvascular ischemic changes. What does that mean? Also, what does an air cell mean?

Aging changes: As we get older, arteries harden and we see small vessel changes in the brain due to aging. They simply mean the brain doesn't work as well as it did when we are young and mostly attest to our slowly diminishing function. These are microvascular ischemic changes. You probably don't notice these changes.
Air cells are bony areas of the skull with air spaces in them- normal. ...Read more

8

8
My grandpa have chronic microvascular ischemic changes. He has deficiency in vit B12,show low O2 in the brain, have memory loss, his behavior has changed?

My grandpa have chronic microvascular ischemic changes. He has deficiency in vit B12,show low O2 in the brain, have memory loss, his behavior has changed?

?vascular dementia: 1. Get the vitamin B-12 into normal range with injections. 2. He may have had small strokes which need to be prevented with medication. 3. Could have Alzheimer's. Any of above separately or together could affect memory and behavior. A neurologist can help. ...Read more

9

9
Mild genaralized atrophy and chronic white matter ischemic changes in my mom report is it serious matter please tell me?

Mild genaralized atrophy and chronic white matter ischemic changes in my mom report is it serious matter please tell me?

Maybe: Mild general atrophy can be seen on ct scans of people with or without symptoms. Chronic white matter ischemic changes can also be seen in symptomatic or asymptomatic people. Be sure your mom gets checked for obstructive sleep apnea, diabetes, hypertension and high cholesterol. These can cause ischemic changes. ...Read more

10

10
Age 66; right hearing loss; MRI; dx: mild chronic deep white matter ischemic changes in the periventricular and subcortical white matter. Please expla?

Age 66; right hearing loss; MRI; dx: mild chronic deep white matter ischemic changes in the periventricular and subcortical white matter. Please expla?

Becoming a senior: These changes in signal in the white matter are believed to be due to small vessels losing their flow. This is a finding in older or senior citizens. It remains to be seen if they amount to anything as we age ...Read more

11

11
What is the meaning of chronic ischemic changes in bilateral frontparietal sub cortical white matter.what is the medicne for this?

What is the meaning of chronic ischemic changes in bilateral frontparietal sub cortical white matter.what is the medicne for this?

Aspirin...: Blood supply to the mentioned areas are compromised. HTN, DM, Vasculitis, Atherosclerosis, Embolism, can be responsible. Starting with aspirin and doing WU is better. ...Read more

12

12
What is mild chronic ischemic changes in bilateral periventricular white matter?

What is mild chronic ischemic changes in bilateral periventricular white matter?

Described often: Presume on mri, white matter lesions as noted, which are usually nonspecific, but can be associated with hypertension, diabetes, or high blood fats causing "hardening of the arteries" (aka, microvascular angiopathy). This pattern might be consistent with ms in some cases, so needs correlation for relevance. Not a description of stroke, but an indication for prevention of future stroke. ...Read more

13

13
Dad, 66, is affected with "chronic ischemic changes in periventri white matter" and "disprop prominence of ventri system c/p to cortical sulci" cure?

Dad, 66, is affected with "chronic ischemic changes in periventri white matter" and "disprop prominence of ventri system c/p to cortical sulci" cure?

Chronic ischemia: What you are seeing on the mr are common aging changes seen on mr. As for a "cure" being available, not at the moment and likely years before any solution. ...Read more

14

14
What is mild chronic ischemic changes in bilateral frontal periventricular white matter?

What is mild chronic ischemic changes in bilateral frontal periventricular white matter?

Nonspecific WM: Nonspecific periventricular white matter changes- These are normally small spots without clinical relevance. They are more common for people with high blood pressure, diabetes, head injuries or in people who smoke. They do not have a defined clinical meaning. ...Read more

15

15
MRI result: "Mild presumed chronic small vessel ischemic changes in the supratentorial white matter." Should I be concerned?

MRI result: "Mild presumed chronic small vessel ischemic changes in the supratentorial white matter."  Should I be concerned?

Atherosclerosis : No. This is normal aging of the brain. However, going forward, make sure that there is good blood pressure control, maintain normal cholesterol and blood sugar levels, and avoid smoking. These steps will slow the progression of atherosclerosis in the brain. ...Read more

16

16
Microvascular chronic ischemic in brain can affect memory?

Microvascular chronic ischemic in brain can affect memory?

Sure can: We term multiple small strokes, lacunar infarcts, and these can mount up and produce "etat lacunaire", or full-blown vascular dementia. Here, the job involves prevention with an appropriate stroke anti platelet, or anti-coagulant approach. ...Read more

17

17
77 year old's MRI — chronic microvascular ischemic disease & shrinking of brain. No diabetes or high BP. Hasn't smoked for 30 yrs. What's the cause?

77 year old's MRI — chronic microvascular ischemic disease & shrinking of brain. No diabetes or high BP. Hasn't smoked for 30 yrs. What's the cause?

Well that's the question: As we age the brain tends to lose fluid content. There are many seniors who do not have this issue while others do. The micro vascular ischemia is not dependent upon diabetes but small vessels that become blocked by many things including blood clots and cholesterol. Often times it doesn't affect the function of the individual. Occasionally it will. ...Read more

18

18
I have tremors on right side for 9 years; left side is normal; I have white matter ischemic changes+ lacune infarcts; no significant plaque; Dx?

I have tremors on right side for 9 years; left side is normal; I have white matter ischemic changes+ lacune infarcts; no significant plaque; Dx?

See a neurologist: Focal tremors could be a sign of Parkinson's disease. You do describe prior strokes, and many lacunar infarcts can also cause tremors. The focality does concern me as I would want to rule out obstruction of carotid or vertebral artery in neck. An experienced neurologist should be able to pin down the causation ...Read more

19

19
What is chronic white matter ischemic disease?

What is chronic white matter ischemic disease?

Lack of blood deep : In the brain. This condition is most commonly seen in individuals with one or all of the following:
1. Hypertension
2. Diabetes
3. Hyperlipidemia (high cholesterol)
4. Cigarette smoking
5. Family history of stroke

Of course there are others but these are most important. Please meet with your neurologist to discuss why and what you can do to help your situation. Good luck and well wishes. ...Read more

20

20
MRA revealed mild ischemic white matter changes. I'm 28. What does that mean??

MRA revealed mild ischemic white matter changes. I'm 28. What does that mean??

Why did you get it?: If the radiologist knew your age and still read the report in that way I think that is a little unusual. But, it kind of depends on the reason you had the MRI done in the first place. Typically, that type of read would be more common for someone who had long-standing hypertension, diabetes, high cholesterol, smoker for many years and so forth. Do you have a copy of the report or the films ...Read more

21

21
CT Scan today showd micro ischemic changes in white matter. What does that mean and how serious is this issue?

CT Scan today showd micro ischemic changes in white matter. What does that mean and how serious is this issue?

White matter changes: Seriousness of the "issue" depends on how severe it is. I'm sure you didn't just wander into a CT facility and made an impulse purchase. Your doctor ordered the CT for a REASON. What was it? The CT isn't the patient; you are. Test results are meaningless without a clinical context. What is it? The ordering doctor is ethically obligated to explain the result to you; or to find someone who can. ...Read more

22

22
Bilateral frontal lobe subcortical white matter showing evidence of small vessel ischemic changes. Is this serious?

Bilateral frontal lobe subcortical white matter showing evidence of small vessel ischemic changes. Is this serious?

NONSPECIFIC : Although the films were read as suggesting ischemia, location might also suggest prior head trauma, congenital lesions of no consequence, genetic or hereditary issues, even underlying inflammatory condition. This is only "serious", if clinically you are having stroke symptoms or you possess uncontrolled blood pressure or elevation of blood lipids. Likely quite non-diagnostic. ...Read more

23

23
Bilateral frontal lobe subcortical white matter showing evidence of small vessel ischemic changes. What does this mean?

Subcortical ischemia: This translates to changes in the smaller blood vessels that lead to loss of blood flow to the area and then scarring. Somewhat like a small silent stroke and frequently seen in people with migraines. The opinions about this have swayed from very worried, to common and mundane and more recently back to looking to stop the damage (help the blood flow, oxygen and glucose status optimize). ...Read more

25

25
My brain MRI states "minimal, early deep white matter small vessel ischemic changes". I am 56. Is this indication of TIA-like events? Leukoarioses?

My brain MRI states "minimal, early deep white matter small vessel ischemic changes". I am 56. Is this indication of TIA-like events? Leukoarioses?

Nonspecific: Can indicate many issues, such as hypertension, smoking, prior head injury, migraine, atherosclerosis. Yes, leukoariosis is the technical term, but is NOT the etiology. Doesn't sound too ominous so far, but check in with a neurologist for further directions. Could make appt with one of our Concierge docs here onsite. ...Read more

26

26
38y f. Brain MRI shows left maxillary polyp, partial empty sella, small chronic ischaemic lesions in subcorticle frontoparietal white matter. Cure?

38y f. Brain MRI shows left maxillary polyp, partial empty sella, small chronic ischaemic lesions in subcorticle frontoparietal white matter. Cure?

Nothing to cure: But try to prevent further damage.

Maxillary sinus polyp is nothing to worry about unless sinus symptoms, then ENT consult.

Partial empty sella cannot be fixed, and nothing to worry about unless abnormal pituitary function — may need to see an endocrinologist.

Ischemic lesions may be within normal limits (allowed 1 per decade of life), but need to understand cause(s) and try to prevent more. ...Read more

27

27
MRI showed minimal nonspecific white matter change = diagnosis: migraines, premature vessel ischemic. Doc said take topamax (topiramate) (24yrold-F). 2nd opinion?

MRI showed minimal nonspecific white matter change = diagnosis: migraines, premature vessel ischemic. Doc said take topamax (topiramate) (24yrold-F). 2nd opinion?

Migraines: White matter lesions described may be seen with migraine, cigarette smoking, head trauma, hypertension, and aging. Would not worry about these lesions, and instead focus upon headache control measures, such as prevention with topirimate. But many other OTC and prescription items which can do as good or better a job without adverse effects from topirimate. Maybe HA specialist can serve your need ...Read more

28

28
Had 3 month long migraine so neurologist sent me for MRA. It revealed severe sinusitis plus mild ischemic white matter changes. I'm 28. What is that?

Had 3 month long migraine so neurologist sent me for MRA. It revealed severe sinusitis plus mild ischemic white matter changes. I'm 28. What is that?

Migraine treatment: Once a diagnosis of migraine has been made, effective management of migraine involves three specific strategies: 1) patient education, 2) nonpharmacological management, and 3) pharmacological (medical) management. See an orofacial pain or headache specialist for evaluation and professional management. ...Read more

29

29
I recently had a CT scan of the brain and I want to know what do these findings actually mean? The findings are as follows: focus of decreased density in the sub-cortical white matter of the left frontal lobe, per-ventricular ischemic change. No mass or m

I recently had a CT scan of the brain and I want to know what do these findings actually mean? The findings are as follows: focus of decreased density in the sub-cortical white matter of the left frontal lobe, per-ventricular ischemic change. No mass or m

Your : Your ct findings are suggestive of cerebrovascular disease, which is usually caused by atherosclerosis (hardening of the arteries). Smokers and people with uncontrolled hypertension or high cholesterol are commonly affected by cerebrovascular disease. The areas around your brain's ventricles (these are simply hollow chambers within your brain) are particularly susceptible to the reduced blood flow caused by this condition -- hence the "peri-ventricular ischemic change." the area of decreased density in your left frontal lobe could be due to a "lacunar infarct" (i.e., a small stroke), which is another common complication of cerebrovascular disease.
Your doctor can help you sort through the potential causes of (and treatment for) cerebrovascular disease. If you're a smoker, quitting would be of great benefit to your brain.
I hope things go well for you! ...Read more