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Doctor insights on: Chronic Microvascular White Matter Ischemic Changes

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What is chronic periventricular white matter microvascular ischemic disease?

What is chronic periventricular white matter microvascular ischemic disease?

Patchy insulation: Chronic means this process has been going on for years in the brain. White matter is the part of the brain where the "communication cables" are, and they are "white" because of myelin insulation. The ventricles are fluid-filled "shock absorber" spaces inside the brain. Ischemic means they have been deprived oxygen, microvascular means in tiny blood vessels. Mini-stroke strips off some insulation. ...Read more

White Matter (Definition)

White matter is one of the two components of the central nervous system and consists of glial cells and myelinated axons that transmit signals from one region of the cerebrum to another and between the cerebrum and lower brain centers. White matter tissue of the freshly cut brain appears pinkish white to the naked eye because myelin is composed largely of lipid ...Read more

Dr. Eric Weisman
Board Certified, Neurology
30 years in practice
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Dr. Eric Weisman
Board Certified, Neurology
30 years in practice
3.0M people helped
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Mild genaralized atrophy and chronic white matter ischemic changes in my mom report is it serious matter please tell me?

Mild genaralized atrophy and chronic white matter ischemic changes in my mom report is it serious matter please tell me?

Maybe: Mild general atrophy can be seen on ct scans of people with or without symptoms. Chronic white matter ischemic changes can also be seen in symptomatic or asymptomatic people. Be sure your mom gets checked for obstructive sleep apnea, diabetes, hypertension and high cholesterol. These can cause ischemic changes. ...Read more

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What is mild chronic ischemic changes in bilateral periventricular white matter?

What is mild chronic ischemic changes in bilateral periventricular white matter?

Described often: Presume on mri, white matter lesions as noted, which are usually nonspecific, but can be associated with hypertension, diabetes, or high blood fats causing "hardening of the arteries" (aka, microvascular angiopathy). This pattern might be consistent with ms in some cases, so needs correlation for relevance. Not a description of stroke, but an indication for prevention of future stroke. ...Read more

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Dad, 66, is affected with "chronic ischemic changes in periventri white matter" and "disprop prominence of ventri system c/p to cortical sulci" cure?

Dad, 66, is affected with "chronic ischemic changes in periventri white matter" and "disprop prominence of ventri system c/p to cortical sulci" cure?

Chronic ischemia: What you are seeing on the mr are common aging changes seen on mr. As for a "cure" being available, not at the moment and likely years before any solution. ...Read more

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MRA revealed mild ischemic white matter changes. I'm 28. What does that mean??

MRA revealed mild ischemic white matter changes. I'm 28. What does that mean??

Why did you get it?: If the radiologist knew your age and still read the report in that way I think that is a little bit unusual. But, it kind of depends on the reason you had the MRI done in the first place. Typically, that type of a read would be more common for someone who had long-standing hypertension, diabetes, high cholesterol, smoker for many years and so forth. Do you have a copy of the report or the films ...Read more

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MRI showed minimal nonspecific white matter change = diagnosis: migraines, premature vessel ischemic. Doc said take topamax (24yrold-F). 2nd opinion?

MRI showed minimal nonspecific white matter change = diagnosis: migraines, premature vessel ischemic. Doc said take topamax (24yrold-F). 2nd opinion?

Migraines: White matter lesions described may be seen with migraine, cigarette smoking, head trauma, hypertension, and aging. Would not worry about these lesions, and instead focus upon headache control measures, such as prevention with topirimate. But many other OTC and prescription items which can do as good or better a job without adverse effects from topirimate. Maybe HA specialist can serve your need ...Read more

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Had 3 month long migraine so neurologist sent me for MRA. It revealed severe sinusitis plus mild ischemic white matter changes. I'm 28. What is that?

Had 3 month long migraine so neurologist sent me for MRA. It revealed severe sinusitis plus mild ischemic white matter changes. I'm 28. What is that?

Migraine treatment: Once a diagnosis of migraine has been made, effective management of migraine involves three specific strategies: 1) patient education, 2) nonpharmacological management, and 3) pharmacological (medical) management. See an orofacial pain or headache specialist for evaluation and professional management. ...Read more

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Dr. Eric Weisman
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