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Doctor insights on: Chronic Microvascular White Matter Ischemic Changes

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Dr. Adam Levy
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White Matter (Definition)

White matter is one of the two components of the central nervous system and consists of glial cells and myelinated axons that transmit signals from one region of the cerebrum to another and between the cerebrum and lower brain centers. White matter tissue of the freshly cut brain appears pinkish white to the naked eye because myelin is composed largely of lipid ...Read more


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What is chronic periventricular white matter microvascular ischemic disease?

What is chronic periventricular white matter microvascular ischemic disease?

Patchy insulation: Chronic means this process has been going on for years in the brain. White matter is the part of the brain where the "communication cables" are, and they are "white" because of myelin insulation. The ventricles are fluid-filled "shock absorber" spaces inside the brain. Ischemic means they have been deprived oxygen, microvascular means in tiny blood vessels. Mini-stroke strips off some insulation. ...Read more

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Dr. Adam Levy
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Mild genaralized atrophy and chronic white matter ischemic changes in my mom report is it serious matter please tell me?

Mild genaralized atrophy and chronic white matter ischemic changes in my mom report is it serious matter please tell me?

Maybe: Mild general atrophy can be seen on ct scans of people with or without symptoms. Chronic white matter ischemic changes can also be seen in symptomatic or asymptomatic people. Be sure your mom gets checked for obstructive sleep apnea, diabetes, hypertension and high cholesterol. These can cause ischemic changes. ...Read more

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Dr. Adam Levy
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31 years in practice
514K people helped
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Age 66; right hearing loss; MRI; dx: mild chronic deep white matter ischemic changes in the periventricular and subcortical white matter. Please expla?

Age 66; right hearing loss; MRI; dx: mild chronic deep white matter ischemic changes in the periventricular and subcortical white matter. Please expla?

Becoming a senior: These changes in signal in the white matter are believed to be due to small vessels losing their flow. This is a finding in older or senior citizens. It remains to be seen if they amount to anything as we age ...Read more

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What is mild chronic ischemic changes in bilateral periventricular white matter?

What is mild chronic ischemic changes in bilateral periventricular white matter?

Described often: Presume on mri, white matter lesions as noted, which are usually nonspecific, but can be associated with hypertension, diabetes, or high blood fats causing "hardening of the arteries" (aka, microvascular angiopathy). This pattern might be consistent with ms in some cases, so needs correlation for relevance. Not a description of stroke, but an indication for prevention of future stroke. ...Read more

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Dad, 66, is affected with "chronic ischemic changes in periventri white matter" and "disprop prominence of ventri system c/p to cortical sulci" cure?

Dad, 66, is affected with "chronic ischemic changes in periventri white matter" and "disprop prominence of ventri system c/p to cortical sulci" cure?

Chronic ischemia: What you are seeing on the mr are common aging changes seen on mr. As for a "cure" being available, not at the moment and likely years before any solution. ...Read more

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What is mild chronic ischemic changes in bilateral frontal periventricular white matter?

What is mild chronic ischemic changes in bilateral frontal periventricular white matter?

Nonspecific WM: Nonspecific periventricular white matter changes- These are normally small spots without clinical relevance. They are more common for people with high blood pressure, diabetes, head injuries or in people who smoke. They do not have a defined clinical meaning. ...Read more

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MRI result: "Mild presumed chronic small vessel ischemic changes in the supratentorial white matter." Should I be concerned?

MRI result: "Mild presumed chronic small vessel ischemic changes in the supratentorial white matter."  Should I be concerned?

Atherosclerosis : No. This is normal aging of the brain. However going forward, make sure that there is good blood pressure control, maintain normal cholesterol and blood sugar levels, and avoid smoking. These steps will slow the progression of atherosclerosis in the brain. ...Read more

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What is chronic white matter ischemic disease?

What is chronic white matter ischemic disease?

Lack of blood deep : In the brain. This condition is most commonly seen in individuals with one or all of the following: 1. Hypertension 2. Diabetes 3. Hyperlipidemia (high cholesterol) 4. Cigarette smoking 5. Family history of stroke of course there are others but these are most important. Please meet with your neurologist to discuss why and what you can do to help your situation. Good luck and well wishes. ...Read more

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Dr. Adam Levy
Board Certified, Obstetrics and Gynecology
31 years in practice
514K people helped
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