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Doctor insights on: Chronic Ischemic White Matter Disease

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White Matter (Definition)

White matter is one of the two components of the central nervous system and consists of glial cells and myelinated axons that transmit signals from one region of the cerebrum to another and between the cerebrum and lower brain centers. White matter tissue of the freshly cut brain appears pinkish white to the naked eye because myelin is composed largely of lipid ...Read more

Dr. Eric Weisman
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What is chronic periventricular white matter microvascular ischemic disease?

What is chronic periventricular white matter microvascular ischemic disease?

Patchy insulation: Chronic means this process has been going on for years in the brain. White matter is the part of the brain where the "communication cables" are, and they are "white" because of myelin insulation. The ventricles are fluid-filled "shock absorber" spaces inside the brain. Ischemic means they have been deprived oxygen, microvascular means in tiny blood vessels. Mini-stroke strips off some insulation. ...Read more

Dr. Eric Weisman
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I recently had an MRI of the brain. The results where as follows mild atrophy and mild periventricular white matter ischemic small vessel disease. Wh?

I recently had an MRI of the brain. The results where as follows mild atrophy and mild periventricular white matter ischemic small vessel disease.  Wh?

Arteriosclerosis : You are taking hydrocodone, tramadol & Lyrica for nagging pain plus Ambien for sleep and Buspirone for anxiety. Combination is heavy stuff. Had migraine but not any more? Microvascular disease is the blockage of tiny vessels-arteriosclerosis. These can happen in heart & kidney as well. Check your lipid profile and possible use of statin. For headache & reevaluation of all your meds see neurologist. ...Read more

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Dad, 66, is affected with "chronic ischemic changes in periventri white matter" and "disprop prominence of ventri system c/p to cortical sulci" cure?

Dad, 66, is affected with "chronic ischemic changes in periventri white matter" and "disprop prominence of ventri system c/p to cortical sulci" cure?

Chronic ischemia: What you are seeing on the mr are common aging changes seen on mr. As for a "cure" being available, not at the moment and likely years before any solution. ...Read more

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What is mild chronic ischemic changes in bilateral periventricular white matter?

What is mild chronic ischemic changes in bilateral periventricular white matter?

Described often: Presume on mri, white matter lesions as noted, which are usually nonspecific, but can be associated with hypertension, diabetes, or high blood fats causing "hardening of the arteries" (aka, microvascular angiopathy). This pattern might be consistent with ms in some cases, so needs correlation for relevance. Not a description of stroke, but an indication for prevention of future stroke. ...Read more

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Mild genaralized atrophy and chronic white matter ischemic changes in my mom report is it serious matter please tell me?

Mild genaralized atrophy and chronic white matter ischemic changes in my mom report is it serious matter please tell me?

Maybe: Mild general atrophy can be seen on ct scans of people with or without symptoms. Chronic white matter ischemic changes can also be seen in symptomatic or asymptomatic people. Be sure your mom gets checked for obstructive sleep apnea, diabetes, hypertension and high cholesterol. These can cause ischemic changes. ...Read more

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38y f. Brain MRI shows left maxillary polyp, partial empty sella, small chronic ischaemic lesions in subcorticle frontoparietal white matter. Cure?

38y f. Brain MRI shows left maxillary polyp, partial empty sella, small chronic ischaemic lesions in subcorticle frontoparietal white matter. Cure?

Nothing to cure: But try to prevent further damage. Maxillary sinus polyp is nothing to worry about unless sinus symptoms, then ENT consult. Partial empty sella cannot be fixed, and nothing to worry about unless abnormal pituitary function - may need to see an endocrinologist. Ischemic lesions may be within normal limits (allowed 1 per decade of life), but need to understand cause(s) and try to prevent more. ...Read more

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Mri report says morphology says in favour of smallt2 and flair hyperintensefoci in bilateral frontal white matter-? Ischemic/? Significant

Mri report says morphology says in favour of smallt2 and flair hyperintensefoci in bilateral frontal white matter-? Ischemic/? Significant

Usually not: This is a very common finding on mris of the brain. Typically it is not significant. However, if you are experiencing neurological symptoms these foci may represent something more sinister and you should see your doctor. ...Read more

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Hi, there are few small foci of high signal in the white matter of both cerebral hemisphere non specific but likely ischemic.What does mean in MRI mr?

Hi, there are few small foci of high signal in the white matter of both cerebral hemisphere non specific but likely ischemic.What does mean in MRI mr?

Review with Doctor: Usually a few small foci are of little concern, and merely mean that there is some small vessel disease, as occurs with high blood pressure, diabetes, or even with migraines. However, 26 is a pretty young age for age related changes, and should at least be viewed by your doctor. ...Read more

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Dr. Eric Weisman
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