Doctor insights on:
Chronic Ischemic Demyelination
Parse the words: Chronic = long-standing. Microvascular = small blood vessel. Ischemic = insufficient blood flow. Technically such a condition can affect any organ in the body but this condition gets most attention due to neurologic involvement. Certain genetic & environmental factors contribute to this condition--that is, there is more than one cause. ...Read more
Nerve fibers have a central axon insulated by myelin covering. Demyelination is damage to the myelin, and typically experienced in multiple sclerosis due to an autoimmune attack by lymphocytes, but may be seen also in hereditary leukodystrophies, acute encephalomyelitis, ...Read more
Drugs exist: Previous answer on stress reduction which is really important.However, medications exist that can help too. It does depend on which demyelinating problem (ms, cdip), and what type as some treatments are more indicated for certain kinds of ms for example.Many are powerful immune-modulating drugs, and can be by mouth, shot or IV depending. Best to see someone skilled in treatment, such as neurologist. ...Read more
Patchy insulation: Chronic means this process has been going on for years in the brain. White matter is the part of the brain where the "communication cables" are, and they are "white" because of myelin insulation. The ventricles are fluid-filled "shock absorber" spaces inside the brain. Ischemic means they have been deprived oxygen, microvascular means in tiny blood vessels. Mini-stroke strips off some insulation. ...Read more
See comments: Are you referring to radiology reading of an MRI of brain? In elderly, often thought that white matter lesions are associated with "microvascular angiopathy", sign of potential atherosclerosis. Maybe potential stroke risk, especially lacunar infarct, but not straightforwards. Your physician needs to assess stroke risk. Spots more likely from migraine or prior injury. ...Read more
Is chronic diffuse sensorimotor peripheral neuropathy with predominant external & secondary demyelinative changes a long-term disability?
It can be: Sensorimotor peripheral neuropathies have many types and various causes. Some of them can be disabling, even long term in some cases. A thorough search will have to include blood tests and urine tests. In some cases spinal tab (lumbar puncture) can be necessary. In delineating the diagnosis. ...Read more
No.: Chronic mesenteric ischemia (cmi) occurs because of poor blood flow to the intestines, classically needing 2 out of 3 blood vessels to the gut with a significant narrowing. The usual symptoms of cmi are abdominal pain after meals, unintended weight loss, and a "fear of eating." the pancreas has such a rich blood supply that poor blood flow to it is not usually a problem. ...Read moreSee 1 more doctor answer
Is stable bilateral frontaoparietal white matter t2w/flair hyperintense signals, probably chronic microvascular ischemic changes called mild stroke?
No: No, Hashimoto's does not cause brain demyelinations. Hashimoto's is an autoimmune thyroid dysfunction which will eventually cause hypothyroidism. During initial stage of Hashimoto's, thyroid function may remain normal or transiently elevated with self resolution. But in long term, most patient with Hashimoto's will develop hypothyroidism requiring thyroid hormone replacement ...Read more
MRI brain results Impression- there is cerebral atrophy with subcortical WMC, consistent wit microangiopathic disease, demyelination, or giliosis?
Covering the bases: That signal that is seen in patients who age is seen very frequently. Most of the time it is what has become known as microangiopathic disease or small vessel disease. Demyelination and gliosis come with a more notable history. Gliosis or scarring and demyelination also produces symptoms that MRI is useful for. Depends on why you had the MRI in the first place. The first entity more common than 2 ...Read more
What is chronic microvascular ischemic disease, chronic migraine, and a disseminating process such as multiple sclerosis mean on MRI? Do I have MS?
You're the patient..: ...not the MRI. Presumably you didn't just wander into an MRI facility & make an impulse purchase. The MRI was ordered by your doctor & for a reason. The radiologist isn't paid to diagnose YOU; (s)he just looks at studies & reports what (s)he sees. Go back to the ordering MD; diagnosing YOU is his/her job. Ask to see the MRI: in radiology, 1 picture is worth 1000 words. ...Read more
Chronic is Typical: Artery disease, especially in the heart arteries, is dominant human behavior, typically starts in childhood yet is typically ignored for decades because it remains asymptomatic until plaque ruptures release debris, triggers clots & suddenly blocks blood flow. These plaque ruptures are the basis for acute symptomatic disease. Thus best to treat the driving factors early, not wait for symptoms. ...Read moreSee 1 more doctor answer
Yes but . . . .: Since pan is a vasculitis, it like the other rheumatological illnesses of this type can cause an associated neuropathy. It would be important to rule out other potential causes like medications, vitamin deficiencies, alcohol, infections, hereditary, diabetes, neurological conditions or vascular compromise. Others too. The onset, time course, distribution, and anatomy can help define it. Emg done? ...Read moreSee 2 more doctor answers
No: Autoimmune thyroiditis can occur in young children, adolescents and adults of any age. We see it most often in children who have a family history of that condition. In many children that we have seen, it was mild but symptomatic enough that their mother recognized the condition and sought treatment. Even with mild disease in children the treatment can have profound benefits. ...Read moreSee 1 more doctor answer
See below: Am not familiar with "unspecified", but transient cerebral ischemia means diminished blood flow to a part of the brain causing clinical symptoms. Since this can be the first sign of an impending stroke, this needs to be fully evaluated and medication started for prevention. See a neurologist and get this fully addressed. ...Read moreSee 1 more doctor answer
What does coronary occlusion acute, arterio-sclerotic cardio vascular disease and acute myocardial infarction mean?
A friend had chronic demyelinating polyneuropathy (cidp), then got chronic lymphocytic leukemia 2 years later. Is cidp paraneoplastic syndrome sometimes?
Not likely: Chronic inflammatory demyelinating polyradiculopathy (cidp) is almost always an autoimmune condition incited by some antecedent infection--c. Jejuni, ebv, cmv, or another infection. Antibodies produced against the virus/ bacteria/ pathogen cross-react with the myelin sheath on the nerve roots, first causing guillain-barre (aidp), then later cidp. It's exceedingly rare that cancer could cause this. ...Read moreSee 2 more doctor answers
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