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Doctor insights on: Chronic Granulomatous Disease Life Expectancy

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What sort of disease is chronic granulomatous disease (c.G.D.)?

What sort of disease is chronic granulomatous disease (c.G.D.)?

Immunodeficiency: The body's immune system is made of 3 kinds of cells: t-cells, b-cells and WBC (white blood cell). Wbcs roam the various tissues and engulf bacteria and fungi they encounter and then digest them inside themselves. When a crucial molecule, the reactive oxygen species (ros) is not present to enable the killing, the infection is not stopped. So these patients get sick very often. ...Read more

Dr. Sanjiv Kaul
29 Doctors shared insights

Chronic Granulomatous Disease (Definition)

Chronic granulomatous disease (CGD) is an inherited disorder. In CGD, immune cells called phagocytes are unable to kill some types of bacteria and fungi. This disorder leads to long-term (chronic) and repeated (recurrent) infections. Recurrent infections should be worked up by a physician ...Read more


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What is the definition or description of: Chronic granulomatous disease?

What is the definition or description of: Chronic granulomatous disease?

Immune dysfunction: Chronic granulomatous disease (CGD) is an inherited disorder. In CGD, immune cells called phagocytes are unable to kill some types of bacteria and fungi. This disorder leads to long-term (chronic) and repeated (recurrent) infections. Recurrent infections should be worked up by a physician to determine the cause. ...Read more

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I have chronic granulomatous disease. Could you tell me what is good for that?

I have chronic granulomatous disease. Could you tell me what is good for that?

Early treatment: People with Chronic Granulomatous disease are prone to infections. Early treatment of any suspected infection is critical. Graulomas may also for in the gastrointestinal system causing colitis so seeing a gastroenterologist regularly would be a good idea if you have any gastrointestinal symptoms. ...Read more

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What is chronic granulomatous disease typically?

What is chronic granulomatous disease typically?

Immunodeficiency: White blood cells (WBC) roam the various tissues and engulf bacteria and fungi they encounter and then digest them inside themselves. When a crucial molecule, the reactive oxygen species (ros) is not present to enable the killing, the infection is not stopped. So these patients get sick often. ...Read more

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What are the tests for chronic granulomatous disease?

Chronic infections: Chronic granulomatous disease (cgd) is a genetic disorder in which immune system cells are unable to kill some types of bacteria and fungi. The disorder leads to long term (chronic) and repeated (recurrent) infections. The condition is often discovered in very early childhood. Milder forms may be diagnosed at a later age. Check this site. Http://www. Ncbi. Nlm. Nih. Gov/pubmedhealth/pmh0002219/. ...Read more

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What are the symptoms of chronic granulomatous disease?

Chronic infections: Chronic granulomatous disease (cgd) is a genetic disorder in which immune system cells are unable to kill some types of bacteria and fungi. The disorder leads to long term (chronic) and repeated (recurrent) infections. The condition is often discovered in very early childhood. Milder forms may be diagnosed at a later age. Check this site. Http://www. Ncbi. Nlm. Nih. Gov/pubmedhealth/pmh0002219/. ...Read more

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What can I try at home to treat chronic granulomatous disease?

What can I try at home to treat chronic granulomatous disease?

Nothing other than..: ...Maintaining good hygiene including frequent hand washing and avoiding direct contact with sick people as much as possible. ...Read more

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What symptoms usually go along with chronic granulomatous disease?

Severe infections: This disease affects the immune system so that they are unable to fight off common germs and get very sick from infections that would be mild in healthy people. These severe infections can include skin or bone infections and abscesses in internal organs (lungs, liver, brain). Children with this disease are healthy at birth but usually develop severe infections in infancy or early childhood. ...Read more

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Is there more than one good way to treat chronic granulomatous disease?

Yes!: Cgd is an immune deficiency that leads to frequent bacterial and fungal infections. Current treatment can include aggressive and prolonged antibiotic, antifungal, and Prednisone use (sometimes continuously for each as prevention), interferon, white blood cell transfusions, stem cell transplantation, and sometimes bone marrow transplantation. ...Read more

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Is it possible for a child to grow out of chronic granulomatous disease?

Is it possible for a child to grow out of chronic granulomatous disease?

No: This is a congenital, metabolic defect that is permanant. Can be addressed however with the specialist. ...Read more

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A friend was just diagnosed with chronic granulomatous disease, is that a serious condition?

Yes.: Chronic granulomatous disease (cgd) is an immune deficiency that leads to frequent and often severe bacterial and fungal infections. Cgd symptom onset is usually in infancy or early childhood, and 90% of patients with it are males. I would add that there are other, very different conditions with similar names, so your friend should clarify this with his or her doctor. ...Read more

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Treatment options for chronic granulomatous disease? Thanks!

Quite a few!: Cgd is an immune deficiency that leads to frequent bacterial and fungal infections. Current treatment can include aggressive and prolonged antibiotic, antifungal, and Prednisone use (sometimes continuously for each as prevention), interferon, white blood cell transfusions, stem cell transplantation, and sometimes bone marrow transplantation. ...Read more

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Looking forward to going on a trip to the beach with friends this year. Already started getting in shape. Now I've been told I have chronic granulomatous disease. How can I explain to them how I got it?

Looking forward to going on a trip to the beach with friends this year. Already started getting in shape. Now I've been told I have chronic granulomatous disease. How can I explain to them how I got it?

You don't have to: You do not have to explain anything to your friends unless you want to! Go and have a great time. You have had this since birth and probably a mild form if it has just recently been diagnosed. You will have to be more vigilant when you are feeling sick as you may need antibiotics for infections sooner than anyone else you know. See comment for more info. ...Read more

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My mother works long hours so I can go to college. When I ask about her, she says she likes to help me. Now she says her doctor told her weeks ago she has chronic granulomatous disease. What will that do to her?

Please see below.: I advise having a meeting with you, her doctor, and her -- it would be unusual for someone to be diagnosed with this at her age, but there are other very different conditions with similar names. Cgd symptom onset is usually in infancy or childhood, and 90% of patients with it are males. Her doctor can tell you what her diagnosis is, and what its impact on her will be. ...Read more

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Chronic granulomatous disordor life expectancy?

Chronic granulomatous disordor life expectancy?

CGD: Must meet with an immune deficiency specialist. Long-term antibiotic treatments may help to reduce infections, but early death is typically a result of repeated lung infections. ...Read more

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Can an autoimmune diseases like Chronic granulomatous has any affect in the grown of uterine fibroid? Just find out I have 5 CM fibroid in my uterus.

Can an autoimmune diseases like Chronic granulomatous has any affect in the grown of uterine fibroid? Just find out I have 5 CM fibroid in my uterus.

Probably not: Hi! If you were my patient I would probably
Have to admit that there is still lots to learn
About autoimmune diseases AND fibroids.
But they are probably independent of each
Other and I would not expect an interaction
Either way.
Hope that helps!
Dr Brown ...Read more

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What to do if I have hilar calcifications suggesting old granulomatous disease. What does it mean?

What to do if I have hilar calcifications suggesting old granulomatous disease. What does it mean?

Just follow up: Your doctor would explain to you the findings in a better way in the context of your clinical picture, at any rate hilar calcification can present old granulomatous disorder or often times just exposure to a fungus "blastomyces" many people in the southern States are exposed and are asymptomatic and the calcifications just appear on the xray, if no symptoms don't worry and keep your follow up ...Read more

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What is granulomatous disease? Is it related to ra?

What is granulomatous disease? Is it related to ra?

CGD: Chronic granulomatous disease is a genetic defect of white blood cells, specifically polymorphonuclear leukocytes. Granulomas, on the other hand, are a form of pathological change in tissues usually due to infections, but other causes as well, such as sarcoid, foreign bodies, and so on. Whether it is related to your RA can best be discussed with your rheumatologist, and would definitely do this. ...Read more

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What does remote granulomatous disease in lungs mean?

What does remote granulomatous disease in lungs mean?

Encounter to TB: If there is a sign of remote granulomatous disease in your lung, it means that the radiologist saw some calcification in your xray.
The majority of these cases means that patient at some point was infected with tuberculosis, but her or his body controlled the infection.
There are other granulomatous diseases beside tuberculosis infection such as histoplasmosis which is endemic in some areas of usa. ...Read more

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Can you tell me what is granulomatous disease and how to differentiate it with auto-immune disorder.?

Can you tell me what is granulomatous disease and how to differentiate it with auto-immune disorder.?

Granulomatous dz: There are infectious and non-infectious types of granulomatous disease. A non-infectious type would be sarcoidosis. Unfortunately no one knows the cause of sarcoidosis. It could indeed be an autoimmune disease. It does respond to steroids. Autoimmune diseases are those in which the immune system attacks specific areas of one's own body. In many of those diseases, blood work can help in diagnosis. ...Read more

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Had CT of chest and it said I had residues of old granulomatous disease what is that?

Had CT of chest and it said I had residues of old granulomatous disease what is that?

Several posibilities: Granulomas are a result of some inflammatory insult to tissues. In the lung they may represent old fungal infection such as histoplasmosis, or may be tuberculosis (in which case you should have a PPD placed and read so that it is part of your medical history). Non infectious causes also occur, such as sarcoidosis, starch granulomas, foreign body granulomas, and on and on. ...Read more

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What does it mean when result say there are changes of old granulomatous disease?

What does it mean when result say there are changes of old granulomatous disease?

Change in activity: Granuloma means a collection of immune cells in an area of body. Usually this happens in a long standing infection such tuberculosis. When the appearance changes in a old tissue, it could mean a reactivation. ...Read more

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What is granulomatous disease?

What is granulomatous disease?

Chronically inflamed: Tissue due to infection, contains granules. If you were referring to CGD, chronic granulomatous disease, is a primary immune deficiency disorder where the white blood cells, phagocytes do not function well, resulting in chronic granulomatous inflammation in many organs secondary to infections with bacteria and fungi ...Read more

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If a CT scan says there's evidence of history of granulomatous disease. You have a 6mm nodule which was 4mm 7mo ago, current sob on exurt, cough, worry?

Yes: If the nodule is growing that means the disease is still active. Having sob is another warning sign. See a pulmonologist soon. ...Read more

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Chest CT scan showed nodules are gone. Report also stated granulomatous disease. What does that mean? I don't have follow up until next week.

Chest CT scan showed nodules are gone. Report also stated granulomatous disease. What does that mean? I don't have follow up until next week.

Benign: Granulomatous disease is usually caused by prior infection by histoplasma fungus. This is benign and quite common. Nothing you describe sounds worrisome. ...Read more

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I just had a chest x-ray that showed minimal old granulomatous disease. Could this cause shortness of breath with minimal exercise (walking up hill)?

I just had a chest x-ray that showed minimal old granulomatous disease. Could this cause shortness of breath with minimal exercise (walking up hill)?

Shouldn't: If the lung involvement is truly "minimal" on CXR or CT scan then this shouldn't compromise your lung function enough to cause respiratory symptoms with minimal exercise. Important to determine etiology of lesions first then look for other causes of shortness of breath. Deconditioning, asthma, heart disease are just a few conditions that can be implicated. See Pulmonologist for further evaluation. ...Read more

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I was just dx with old granulomatous disease per CT scan. Could this be caused from my 35 yr history of genital herpes?

I was just dx with old granulomatous disease per CT scan. Could this be caused from my 35 yr history of genital herpes?

Not herpes related: Herpes, genital or otherwise, doesn't cause anything like this. These are entirely unrelated problems. Many past infections could cause "old granulomatous disease" detected by chest Xray or CT, and most cases like this turn out not to be serious. But don't take the chance -- follow your doctor's advice about further evaluation. But don't worry at all about herpes. Good luck! ...Read more

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I have the same shortness of breath when walking on a incine. Also had a CT with old granulomatous disease. Have hoarseness and right vocal c?

I have the same shortness of breath when walking on a incine. Also had a CT with old granulomatous disease. Have hoarseness and right vocal c?

You might be: Describing something serious, but hard to tell here. Get to the doctor who ordered the scan to see what is recommended. ...Read more

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CT of my T-spine shows evidence of granulomatous disease w/in chest w/calcified mediastinal & hilar lymph nodes. What does that mean? C Doc ASAP??

CT of my T-spine shows evidence of granulomatous disease w/in chest w/calcified mediastinal & hilar lymph nodes. What does that mean? C Doc ASAP??

Mgt: A virtual appointment may be booked to upload the report for review. The findings may be caused by a number of conditions. Among these are infections, TB, malignancy.
A PET scan may be indicated. ...Read more