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Doctor insights on: Chronic Granulomatous Disease Immune Diseases

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What sort of disease is chronic granulomatous disease (c.G.D.)?

What sort of disease is chronic granulomatous disease (c.G.D.)?

Immunodeficiency: The body's immune system is made of 3 kinds of cells: t-cells, b-cells and WBC (white blood cell). Wbcs roam the various tissues and engulf bacteria and fungi they encounter and then digest them inside themselves. When a crucial molecule, the reactive oxygen species (ros) is not present to enable the killing, the infection is not stopped. So these patients get sick very often. ...Read more

Dr. John Chiu
528 doctors shared insights

Immune Diseases (Definition)

The immune system is a complex and highly developed system, yet its mission is simple: to seek and kill infectious invaders, and protect us from harmful substances. Immune system disorders occur when the immune system is either under or overactive. When the immune system is defective or underactive, people are susceptible mainly to recurrent infections (immune deficiency diseases). In severe cases, the infections are life-threatening. When the immune system is overactive, the immune system attacks our own organs causing diseases of several kinds: "autoimmune" diseases such as lupus erythematosus and rheumatoid arthritis; certain diseases of the thyroid; and certain muscle and nerve diseases, to name just a few. Allergies and asthma also are the result of ...Read more


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Treatment options for chronic granulomatous disease? Thanks!

Quite a few!: Cgd is an immune deficiency that leads to frequent bacterial and fungal infections. Current treatment can include aggressive and prolonged antibiotic, antifungal, and Prednisone use (sometimes continuously for each as prevention), interferon, white blood cell transfusions, stem cell transplantation, and sometimes bone marrow transplantation. ...Read more

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What can I try at home to treat chronic granulomatous disease?

What can I try at home to treat chronic granulomatous disease?

Nothing other than..: ...Maintaining good hygiene including frequent hand washing and avoiding direct contact with sick people as much as possible. ...Read more

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What symptoms usually go along with chronic granulomatous disease?

Severe infections: This disease affects the immune system so that they are unable to fight off common germs and get very sick from infections that would be mild in healthy people. These severe infections can include skin or bone infections and abscesses in internal organs (lungs, liver, brain). Children with this disease are healthy at birth but usually develop severe infections in infancy or early childhood. ...Read more

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Is it possible for a child to grow out of chronic granulomatous disease?

Is it possible for a child to grow out of chronic granulomatous disease?

No: This is a congenital, metabolic defect that is permanant. Can be addressed however with the specialist. ...Read more

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What is the definition or description of: Chronic granulomatous disease?

What is the definition or description of: Chronic granulomatous disease?

Immune dysfunction: Chronic granulomatous disease (CGD) is an inherited disorder. In CGD, immune cells called phagocytes are unable to kill some types of bacteria and fungi. This disorder leads to long-term (chronic) and repeated (recurrent) infections. Recurrent infections should be worked up by a physician to determine the cause. ...Read more

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I have chronic granulomatous disease. Could you tell me what is good for that?

I have chronic granulomatous disease. Could you tell me what is good for that?

Early treatment: People with Chronic Granulomatous disease are prone to infections. Early treatment of any suspected infection is critical. Graulomas may also for in the gastrointestinal system causing colitis so seeing a gastroenterologist regularly would be a good idea if you have any gastrointestinal symptoms. ...Read more

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Looking forward to going on a trip to the beach with friends this year. Already started getting in shape. Now i've been told I have chronic granulomatous disease. How can I explain to them how I got it?

Looking forward to going on a trip to the beach with friends this year. Already started getting in shape. Now i've been told I have chronic granulomatous disease. How can I explain to them how I got it?

You don't have to: You do not have to explain anything to your friends unless you want to! go and have a great time. You have had this since birth and probably a mild form if it has just recently been diagnosed. You will have to be more vigilant when you are feeling sick as you may need antibiotics for infections sooner than anyone else you know. See comment for more info. ...Read more

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What is chronic granulomatous disease typically?

What is  chronic granulomatous disease typically?

Immunodeficiency: White blood cells (WBC) roam the various tissues and engulf bacteria and fungi they encounter and then digest them inside themselves. When a crucial molecule, the reactive oxygen species (ros) is not present to enable the killing, the infection is not stopped. So these patients get sick often. ...Read more

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What are the tests for chronic granulomatous disease?

Chronic infections: Chronic granulomatous disease (cgd) is a genetic disorder in which immune system cells are unable to kill some types of bacteria and fungi. The disorder leads to long term (chronic) and repeated (recurrent) infections. The condition is often discovered in very early childhood. Milder forms may be diagnosed at a later age. Check this site. http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0002219/. ...Read more

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What are the symptoms of chronic granulomatous disease?

Chronic infections: Chronic granulomatous disease (cgd) is a genetic disorder in which immune system cells are unable to kill some types of bacteria and fungi. The disorder leads to long term (chronic) and repeated (recurrent) infections. The condition is often discovered in very early childhood. Milder forms may be diagnosed at a later age. Check this site. http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0002219/. ...Read more

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Is there more than one good way to treat chronic granulomatous disease?

Yes!: Cgd is an immune deficiency that leads to frequent bacterial and fungal infections. Current treatment can include aggressive and prolonged antibiotic, antifungal, and Prednisone use (sometimes continuously for each as prevention), interferon, white blood cell transfusions, stem cell transplantation, and sometimes bone marrow transplantation. ...Read more

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A friend was just diagnosed with chronic granulomatous disease, is that a serious condition?

Yes.: Chronic granulomatous disease (cgd) is an immune deficiency that leads to frequent and often severe bacterial and fungal infections. Cgd symptom onset is usually in infancy or early childhood, and 90% of patients with it are males. I would add that there are other, very different conditions with similar names, so your friend should clarify this with his or her doctor. ...Read more

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My mother works long hours so I can go to college. When I ask about her, she says she likes to help me. Now she says her doctor told her weeks ago she has chronic granulomatous disease. What will that do to her?

Please see below.: I advise having a meeting with you, her doctor, and her -- it would be unusual for someone to be diagnosed with this at her age, but there are other very different conditions with similar names. Cgd symptom onset is usually in infancy or childhood, and 90% of patients with it are males. Her doctor can tell you what her diagnosis is, and what its impact on her will be. ...Read more

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Can you tell me what is granulomatous disease and how to differentiate it with auto-immune disorder.?

Can you tell me what is granulomatous disease and how to differentiate it with auto-immune disorder.?

Granulomatous dz: There are infectious and non-infectious types of granulomatous disease. A non-infectious type would be sarcoidosis. Unfortunately no one knows the cause of sarcoidosis. It could indeed be an autoimmune disease. It does respond to steroids. Autoimmune diseases are those in which the immune system attacks specific areas of one's own body. In many of those diseases, blood work can help in diagnosis. ...Read more

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Can an autoimmune diseases like Chronic granulomatous has any affect in the grown of uterine fibroid? just find out i have 5 CM fibroid in my uterus.

Can an autoimmune diseases like Chronic granulomatous has any affect in the grown of uterine fibroid? just find out i have 5 CM fibroid in my uterus.

Probably not: Hi! If you were my patient I would probably Have to admit that there is still lots to learn About autoimmune diseases AND fibroids. But they are probably independent of each Other and I would not expect an interaction Either way. Hope that helps! Dr Brown ...Read more

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What does it mean when result say there are changes of old granulomatous disease?

What does it mean when result say there are changes of old granulomatous disease?

Change in activity: Granuloma means a collection of immune cells in an area of body. Usually this happens in a long standing infection such tuberculosis. When the appearance changes in a old tissue, it could mean a reactivation. ...Read more

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What to do if I have hilar calcifications suggesting old granulomatous disease. what does it mean?

What to do if I have hilar calcifications suggesting old granulomatous disease. what does it mean?

Just follow up: Your doctor would explain to you the findings in a better way in context with your clinical picture, at any rate hilar calcification can present old granulomatous disorder or often times just exposure to a fungus "bladtomyces" many people in the southern States are exposed and are asymptomatic and the calcifications just appear on the xray, if no symptoms don't worry and keep your follow up ...Read more

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What is granulomatous disease? Is it related to ra?

What is granulomatous disease? Is it related to ra?

CGD: Chronic granulomatous disease is a genetic defect of white blood cells, specifically polymorphonuclear leukocytes. Granulomas, on the other hand, are a form of pathological change in tissues usually due to infections, but other causes as well, such as sarcoid, foreign bodies, and so on. Whether it is related to your RA can best be discussed with your rheumatologist, and would definitely do this. ...Read more

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What does remote granulomatous disease in lungs mean?

What does remote granulomatous disease in lungs mean?

Encounter to TB: If there is a sign of remote granulomatous disease in your lung, it means that the radiologist saw some calcification in your xray. The majority of these cases means that patient at some point was infected with tuberculosis, but her or his body controlled the infection. There are other granulomatous diseases beside tuberculosis infection such as histoplasmosis which is endemic in some areas of usa. ...Read more

Dr. Stephen Scholand
25 doctors shared insights

Chronic Granulomatous Disease (Definition)

Chronic granulomatous disease (CGD) is an inherited disorder. In CGD, immune cells called phagocytes are unable to kill some types of bacteria and fungi. This disorder leads to long-term (chronic) and repeated (recurrent) infections. Recurrent infections should be worked up by a physician ...Read more