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Doctor insights on: Chronic Granulomatous Disease Immune Diseases

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What sort of disease is chronic granulomatous disease (c.G.D.)?

What sort of disease is chronic granulomatous disease (c.G.D.)?

Immunodeficiency: The body's immune system is made of 3 kinds of cells: t-cells, b-cells and WBC (white blood cell). Wbcs roam the various tissues and engulf bacteria and fungi they encounter and then digest them inside themselves. When a crucial molecule, the reactive oxygen species (ros) is not present to enable the killing, the infection is not stopped. So these patients get sick very often. ...Read more

Dr. John Chiu
522 doctors shared insights

Immune Diseases (Definition)

The immune system is a complex and highly developed system, yet its mission is simple: to seek and kill infectious invaders, and protect us from harmful substances. Immune system disorders occur when the immune system is either under or overactive. When the immune system is defective or underactive, people are susceptible mainly to recurrent infections (immune deficiency diseases). In severe cases, the infections are life-threatening. When the immune system is overactive, the immune system attacks our own organs causing diseases of several kinds: "autoimmune" diseases such as lupus erythematosus and rheumatoid arthritis; certain diseases of the thyroid; and certain muscle and nerve diseases, to name just a few. Allergies and asthma also are the result of ...Read more


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Treatment options for chronic granulomatous disease? Thanks!

Quite a few!: Cgd is an immune deficiency that leads to frequent bacterial and fungal infections. Current treatment can include aggressive and prolonged antibiotic, antifungal, and Prednisone use (sometimes continuously for each as prevention), interferon, white blood cell transfusions, stem cell transplantation, and sometimes bone marrow transplantation. ...Read more

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What can I try at home to treat chronic granulomatous disease?

What can I try at home to treat chronic granulomatous disease?

Nothing other than..: ...Maintaining good hygiene including frequent hand washing and avoiding direct contact with sick people as much as possible. ...Read more

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What symptoms usually go along with chronic granulomatous disease?

Severe infections: This disease affects the immune system so that they are unable to fight off common germs and get very sick from infections that would be mild in healthy people. These severe infections can include skin or bone infections and abscesses in internal organs (lungs, liver, brain). Children with this disease are healthy at birth but usually develop severe infections in infancy or early childhood. ...Read more

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Is it possible for a child to grow out of chronic granulomatous disease?

Is it possible for a child to grow out of chronic granulomatous disease?

No: This is a congenital, metabolic defect that is permanant. Can be addressed however with the specialist. ...Read more

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I have chronic granulomatous disease. Could you tell me what is good for that?

I have chronic granulomatous disease. Could you tell me what is good for that?

Early treatment: People with Chronic Granulomatous disease are prone to infections. Early treatment of any suspected infection is critical. Graulomas may also for in the gastrointestinal system causing colitis so seeing a gastroenterologist regularly would be a good idea if you have any gastrointestinal symptoms. ...Read more

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Looking forward to going on a trip to the beach with friends this year. Already started getting in shape. Now i've been told I have chronic granulomatous disease. How can I explain to them how I got it?

Looking forward to going on a trip to the beach with friends this year. Already started getting in shape. Now i've been told I have chronic granulomatous disease. How can I explain to them how I got it?

You don't have to: You do not have to explain anything to your friends unless you want to! go and have a great time. You have had this since birth and probably a mild form if it has just recently been diagnosed. You will have to be more vigilant when you are feeling sick as you may need antibiotics for infections sooner than anyone else you know. See comment for more info. ...Read more

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What is chronic granulomatous disease typically?

What is  chronic granulomatous disease typically?

Immunodeficiency: White blood cells (WBC) roam the various tissues and engulf bacteria and fungi they encounter and then digest them inside themselves. When a crucial molecule, the reactive oxygen species (ros) is not present to enable the killing, the infection is not stopped. So these patients get sick often. ...Read more

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What are the tests for chronic granulomatous disease?

Chronic infections: Chronic granulomatous disease (cgd) is a genetic disorder in which immune system cells are unable to kill some types of bacteria and fungi. The disorder leads to long term (chronic) and repeated (recurrent) infections. The condition is often discovered in very early childhood. Milder forms may be diagnosed at a later age. Check this site. http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0002219/. ...Read more

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What are the symptoms of chronic granulomatous disease?

Chronic infections: Chronic granulomatous disease (cgd) is a genetic disorder in which immune system cells are unable to kill some types of bacteria and fungi. The disorder leads to long term (chronic) and repeated (recurrent) infections. The condition is often discovered in very early childhood. Milder forms may be diagnosed at a later age. Check this site. http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0002219/. ...Read more

Dr. Gregory Moneta
17 doctors shared insights

Chronic Granulomatous Disease (Definition)

Chronic granulomatous disease is a dysfunction of the immune system where white blood cells are unable to effectively swallow up and destroy bacteria. People with this disease are more prone to ...Read more