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Doctor insights on: Chronic Cyclic Neutropenia

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Can jak 2 positive. Polycythemia vera cause chronic low grade fevers?

Can jak 2 positive. Polycythemia vera cause chronic low grade fevers?

No: Pv by itself does'nt cause low grade fevers. However, pv can increase your risk to have blood clots and blood clots can give you low grade fevers also, pv can transform into other condition i.E myelofibrosis as well as mds/ acute leukemia in about 20%-30%). Low grade fevers occur quite commonly in myelofibrosis and acute leukemia. See your md to rule out other condition i.e. Autoimmune , infection. ...Read more

Dr. Michael Engel
123 doctors shared insights

Neutropenia (Definition)

Defined numerically as an absolute neutrophil count (anc) less than 1500. From there it is subdivided into mild (1000-1500), moderate (500-1000) and severe (<500). Folks with severe neutropenia are at increased risk for bacterial infections. Mild to moderate, less so. The reason for neutropenia needs to be determined. Treatments range from observation to stem cell ...Read more


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Is chronic pancytopenia anemia curable?

Is chronic pancytopenia anemia curable?

Depends on cause: Chronic pancytopenia means low white & red cells and low platelets. Reversible causes such as nutritional deficinecies, immune disorders, drug-related can be treated effectively. However, patientsw with inherited conditions or bone marrow disorders need a detailed work-up and treatments may not be effective. ...Read more

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Chronic fatigue syndrome--same as ebv?

Chronic fatigue syndrome--same as ebv?

Chronic fatigue: Although some people with cfs have have some antibodies suggesting recent ebv infection, most do not. There are probably multiple triggers for cfs. ...Read more

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How can chronic myelogenous leukemia cause hepatomegaly?

How can chronic myelogenous leukemia cause hepatomegaly?

Infiltration: The speen does enlarge in this disease. The causes include direct inflitration. Another is production of other blood elements (extramedullary hematopoesis) in the speen in response to either replacement of the marrow with CML or scar. The scarring is called myelofibrosis. ...Read more

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What is chronic myelogenous leukemia (cml)?

What is chronic myelogenous leukemia (cml)?

White cell cancer: The bone marrow cells that produce granulocytes (needed to fight infections) grow out of control and are present in large numbers in the blood and other organs. The disease is quite treatable these days because of targeted therapy and long lasting remissions are possible in most people. ...Read more

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What are the causes of chronic moderate autoimmune neutropenia & moderate-severe thrombocytopenia with giant platelets? Occasionally anemic.

What are the causes of chronic moderate autoimmune neutropenia & moderate-severe thrombocytopenia with giant platelets? Occasionally anemic.

Autoimmunity: The development of an autoimmune disease is most likely from impaired regulation of the immune function leading to immunologic attack on one's own tissue. The presence of one autoimmune disease increases the risk to develop another one probably from the impaired regulation. However we have still much to learn about autoimmunity as to why some people are more prone to it (female are more at risk). ...Read more

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What is chronic myelogenous leukemia?

A blood cancer: CML is a blood cancer that develops slowly (hence chronic). If untreated it will eventually be life threatening. It is associated a unique chromosomal injury, the philadelphia chromosome. New drugs (tkis) target this damage and reliably produce remissions in early stage patients that often are long lasting. ...Read more

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Chronic sinusitis and chronic lymphocytic leukemia--not good together?

Low IgG?: agreed. Frequent bacterial infection associated with CLL may be due to hypogammaglobulinemia (Low amount of antibodies, also called low IgG). That's treatable with monthly infusion of IVIG (intravenous immune globulin). Discuss with hematologist/oncologist. ...Read more

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What is chronic myeloid leukemia?

What is chronic myeloid leukemia?

Marrow cancer: CML is a marrow malignancy characterized by excessive number of white blood cells with various degrees of maturation. Most CML patients have deficient number of red cells and platelets. CML responds dramatically to oral agents called tyrosine kinase inhibitors. Examples are Gleevec and Sprycel (dasatinib). ...Read more

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Idiopathic recurrent acute mild chronic pancreatitis CURE ?

Idiopathic recurrent acute mild chronic pancreatitis CURE ?

Unknown.: Idiopathic means that we don't know why it happens. If we don't know why it happens then we cannot make any logical assumption as to how to cure it. Further information could be helpful. Are you diabetic? Are you overweight? What kind of diet do you have? You drink alcohol ever? Is there anything that you eat that seems to make it worse? Do you have high cholesterol or high triglycerides? ...Read more

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Does having 1 autoimmune disorder predispose u2 others? Mom with hoshimoto's>psoriatic arthritis>viral hepatitis>acute myeloid leukemia.

Does having 1 autoimmune disorder predispose u2 others? Mom with hoshimoto's>psoriatic arthritis>viral hepatitis>acute myeloid leukemia.

Yes: The presence of an autoimmune disorder points to dysregulation of the immune system and thus one is far more likely to have other autoimmune diseases . However, it is not directly linked to viral hepatitis or AML. ...Read more

Dr. Le Wang Dr. Wang
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Can pernicious anemia or severe vitamin B12 deficiency cause chronic non-specific duodenitis??

Dr. Le Wang Dr. Wang
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Can pernicious anemia or severe vitamin B12 deficiency cause chronic non-specific duodenitis??

Not clear: No clear evidence for the causal-effect relationship between the two. PA is an autoimmue-mediated destruction of parietal cells in stomach, resuling in impairmnent of B12 absorption. Certainly it is possible that pernicious anemia may co-exist or exacerbate duodenitis via immune process or loss of balance in duodenal fluid, or anemia. But the causal-effect relationship is not well established. ...Read more

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What causes acute immune deficiency syndrome?

What causes acute immune deficiency syndrome?

HIV: I think you mean "acquired, " not "acute." the cause is HIV infection. ...Read more

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Is chronic neutropenia a type of leukemia?

No: Chronic neutropenia is not a type of leukemia. However, a very low neutrophil count can increase the risk for serious and recurrent infections. ...Read more

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How is acute myeloid leukemia different from chronic lymphoma leukemia?

How is acute myeloid leukemia different from chronic lymphoma leukemia?

Different cell type: Leukemias typically originate when one of the white blood cell types starts multiplying out of control and preventing the normal cells from doing their job. There are many types of white blood cells and the subtype of leukemia or lymphoma or myeloma depends on which subtype is out of control. ...Read more

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Which of the following are auto-immune conditions? Hypothyroidism Coeliac Disease Endometriosis Chronic Fatigue Syndrome (CFS)

Comments: We are learning that the immune system is playing a huge role in many known diseases, and Celiac is certainly auto-immune mediated, and several thyroid disorders are too. Chronic fatigue is often a manifestation of other disorders, and is not considered a separate disease per se. Am unaware of current concepts regarding endometriosis. Should ask OB-GYN specialist. ...Read more

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Is likely that chronic lymphocytic leukemia (cll) live?

Is likely that chronic lymphocytic leukemia (cll) live?

Yes: Many CLL patient's live a long and productive life. Having said that it is a leukemia , it will eventually need therapy. ...Read more

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