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Doctor insights on: Chronic Biliary Cirrhosis

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Is primary biliary cirrhosis hereditary?

Is primary biliary cirrhosis hereditary?

Basically no: There's a pair of genes that carry the ability to develop the disease and these run in families, but it's not inherited like sickle cell, huntington's or some of the other familiar entities. http://www.medicalnewstoday.com/releases/151640.php. ...Read more

Dr. Steven Griggs
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Biliary (Definition)

Biliary means anything related to the production, storage, secretion, or flow of bile, whether in the liver, bile ducts, gallbladder, ...Read more


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What are the tests for biliary cirrhosis?

What are the tests for biliary cirrhosis?

Autoantibody &Biopsy: In addition to abnormal blood tests due to malfunction of liver, patients with primary biliary cirrhosis have peculiar autoantibodies, anti-mitochondrial antibodies. Blood tests and imaging suggest cirrhosis, confirmation requires biopsy (usually needle biopsy) and examination of the tissue by a pathologist. ...Read more

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What exactly is primary biliary cirrhosis?

What exactly is primary biliary cirrhosis?

Liver disease: Primary biliary cirrhosis is an autoimmune liver disease seen most commonly in women in the 4th to 5th decade of life. It generally presents with unexplained itching and occasionally jaundice. It is frequently found on routing screening liver tests which may show an elevated alkaline phosphotase. Though not curable it is treatable and treatment slows the progression to cirrhosis. ...Read more

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What are the symptoms of biliary cirrhosis?

Jaundice & itching: Primary biliary cirrhosis is an autoimmune phenomenon and may be associated with damage to other organs. The prominent symptoms of biliary cirrhosis are jaundice and itching. With progression symptoms of liver failure, e.g., edema, bleeding, ascites etc appear. ...Read more

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How can I treat primary biliary cirrhosis ?

Ursodiol: There is not much available to treat primary biliary cirrhosis, but ursodiol helps normalize the liver enzymes. For other therapies you should discuss with a hepatologist. ...Read more

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Describe the features of biliary cirrhosis.?

Describe the features of biliary cirrhosis.?

Liver failure: There are many things that happen with cirrhosis, depending on how severe it is. These include confusion, bleeding from the GI tract, jaundice, fluid buildup in the belly, increased risk for liver cancer, and other symptoms. ...Read more

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What happens when you have biliary cirrhosis?

What happens when you have biliary cirrhosis?

Liver failure: Biliary cirrhosis causes progressive damage to the liver. There is fibrosis (hardening) of the substance of the liver, increasing pressure in the blood supply, and slowly damaging the cells. Sepending on the cause of cirrhosis, there is very little that will cause reversal of the damage. ...Read more

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If you get biliary cirrhosis, how do you feel?

If you get biliary cirrhosis, how do you feel?

Depends: Some patients with biliary cirrhosis have no symptoms. Others have fatigue and other have severe itching. If you have this condition, you should see your doctor. ...Read more

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What is the cause of primary biliary cirrhosis?

Autoimmune: An autoimmune disorder in which the body attacks it's own liver. ...Read more

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Who is most likely to develop biliary cirrhosis?

Who is most likely to develop biliary cirrhosis?

PBC--who gets it: 90% of pbc patients are female. Age ranges 20-80, but typically patients are 40-60. The disease is world-wide, & affects asians, caucasians, jews, african. Family clustering is common in sisters, twins, daughters, mothers. While environmental factors can't be ignored, a strong immunogenetic background for pbc that runs in families is suggested. Early sxs: fatigue, itching before jaundice, RUQ pain. ...Read more

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Upper Abdomen (Definition)

Draw a transverse line through the umbilicus and the upper abdomen includes every part of the belly above this line and below the ...Read more


Dr. Tanya Russo
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Primary Biliary Cirrhosis (Definition)

A condition where the bile ducts of the liver break down. This causes a buildup of bile in the liver, including ...Read more