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Doctor insights on: Chromosomal Nondisjunction Causes

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How many chromosome defects cause retardation?

Hundreds at least: We only know about a few hundred, probably thousands possible as each human is unique as are their choomasome array. ...Read more

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Are all diseases caused by a problem on one of our chromosomes?

Are all diseases caused by a problem on one of our chromosomes?

No, many reasons: Most diseases are caused by infectious agents (viruses, bacteria, fungus, molds, parasites). Some are caused by environmental toxins and some are by defective chromosomes. ...Read more

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Which chromosome causes cml?

Which chromosome causes cml?

Chromosomes 9 and 22: ...are abnormally spliced together in most cases of CML forming a characteristic translocation referred to as the Philadelphia chromosome. At the molecular level this causes a fusion of two genes (BCR and Abl). ...Read more

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How is progeria caused in the chromosomes?

How is progeria caused in the chromosomes?

New mutation of gene: there is no particular pattern like autosomal dominant,recessive or x-linked. it is new mutation go genes ...Read more

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Is Down syndrome always caused by a defect in the 21 chromosome?

Is Down syndrome always caused by a defect in the 21 chromosome?

Extra chromosome 21.: Either complete or partial trisomy for chromosome 21 is always responsible for down syndrome. ...Read more

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I have a correction to make: was is caused by a mutation in the x chromosome. Females are the carriers and males are affected. ?

I have a correction to make:  was is caused by a mutation in the x chromosome. Females are the carriers and males are affected.  ?

Confused: This appears to be an add on to a previous question. Your questions are never linked on the site & there is no way we can review them. Each question must have basic background information and a related question.It is hard to comment when we don't know what condition you are asking about. ...Read more

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Do abnormal chromosomes cause cancer?

Do abnormal chromosomes cause cancer?

Sometimes: Many cancers seem to have a genetic component. For example, those who have Down syndrome (an extra chromosome #21) are more likely to get leukemia than those who do not have abnormal chromosomes. However, many of the minor chromosome changes are not associated with an increased risk of getting cancer. It all depends on the chromosome problem itself. ...Read more

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Dwarfism is caused by the mutation of which chromosome?

Dwarfism is caused by the mutation of which chromosome?

Many types: There are many different types, for example, the most common type is achondroplasia which is on the short arm of chromosome 4. ...Read more

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Which type of chromosomal mutation causes down syndrome?

Which type of chromosomal mutation causes down syndrome?

Not mutation,number : Down syndrome is an abnormality of chromosome numbers, not a trait or mutation in the gene code. During conception only one of chromosome of each pair is given by both parents to the fertile egg.If a parent adds their 2 nbr 21chm to the other parents nbr 21, 3 end up in the egg ; the excess 21 causes the all the problems.Rare forms are causes by a extra piece of a 21, but that's another issue. ...Read more

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What is the main cause of chromosomal abnormality in fetus?

What is the main cause of chromosomal abnormality in fetus?

Defect in gamete: Either the egg (usually) or sperm carries an extra chromosome (chm) to conception.The fetus ends up with 3 of that chm along with normal pairs of all the others. The third chm will cause a disruption in the code reading that goes into making the organs and brain. The newborn will be born with these defects. ...Read more

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How does an extra chromosome set cause big problems for the baby?

How does an extra chromosome set cause big problems for the baby?

Multiorgan effects.: Aneuploidy (i.e. One extra or missing chromosome) is a group of major genetic disorders that can affect all organ systems, more commonly the heart, brain and kidneys. Examples include Down syndrome (mongolism) and edwards' syndrome (usually lethal). The exact mechanism by which the chromosomal aberrration leads to these effects is not entirely clear but may have to do with gene silencing. ...Read more

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What chromosome causes myofibrillar myopathy?

What chromosome causes myofibrillar myopathy?

Several: Changes in these genes are associated with myofibrillar myopathy.
Bag3
cryab
des
flnc
ldb3
myot
you would need to check each of these for their chromosome position. ...Read more

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What is the gene or chromosome that causes dwarfism?

What is the gene or chromosome that causes dwarfism?

Genes on chromosomes: the knowledge of the osteochondrodystrophies causing dwarfism has in some cases reached the molecular level. There are dozens of different kinds. Some are much better elucidated than others. In some, therapy has become available. ...Read more

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Does DNA or genes cause chromosomal abnormalities?

Does DNA or genes cause chromosomal abnormalities?

Chromosomal: Chromosomes are the packaging for the genes. Genes are made up of dna. Chromosomal abnormalities are extra chromosomes, deletions, duplications, or translocations of large chunks of dna. ...Read more

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What mutation of chromosome 1 can cause cataracts?

What mutation of chromosome 1 can cause cataracts?

Various mutations: There are many syndromes associated with mutations in Chr 1 that are associated wtih cataracts: ie Retinitis Pigmentosa; 1.35-Mb deletion within 1q21.1
More info: eyedoc2020@blogspot.com ...Read more

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What mutation of chromosome 1 can cause cataracts?

What mutation of chromosome 1 can cause cataracts?

Various: There are many syndromes associated with mutations in Chr 1 that are associated wtih cataracts: ie Retinitis Pigmentosa; 1.35-Mb deletion within 1q21.1
More info: eyedoc2020@blogspot.com ...Read more

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Is there a treatment for chromosome problems that causes miscarriage?

Is there a treatment for chromosome problems that causes miscarriage?

Not enough informati: there are different treatments for different situations that possibly would be appropriate for you but there is no way I can tell without knowing why you believe that chromosome problems cause miscarriages.sometimes they do, and sometimes they don't. You should consider seeing a clinical geneticistto review your genetic historyAnd provide you with informed counseling. ...Read more

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What chromosome can cause fetal alcohol syndrome?

What chromosome can cause fetal alcohol syndrome?

Fetal alcohol: Not a gene to cause it. Just the amount of alcohol imbibed during the pregnancy that damage the fetus. ...Read more

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What chromosome carries the gene that can cause dwarfism?

What chromosome carries the gene that can cause dwarfism?

Probably all of them: There are a few hundred different genetic loci that produce dwarfism. Achondroplastic dwarfism is usually the result of a mutation on chromosome 4. ...Read more

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What kind of chromosomal mutation causes the cri du chat syndrome?

Chromosome deletion: Cri du chat is a rare genetic disorder to to chromosome deletion on chromosome 5. See the good discussion of it here: https://en.wikipedia.org/wiki/Cri_du_chat

Here's a great organization formed to educate and support: https://fivepminus.org/ ...Read more

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Could you tell me what genetic disorder is caused by only having one chromosome 12?

Could you tell me what genetic disorder is caused by only having one chromosome 12?

Embryonic demise: A fertilized egg missing a chromosome 12 can not survive. Minute pieces missing from a single chromosome 12 will be missing or disabling the active gene or genes which are normally present there. If only one set of genes doesn't cause trouble, everything will be ok. However, the imbalance may cause potentially over a thousand different disorders. http://ghr.nlm.nih.gov/chromosome/12 ...Read more

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What chromosomes cause the genetic disorder achondroplasia?

FGFR3 gene: Achondroplasia is a mutation in the fibroblast growth factor receptor 3, which is an inhibitor that regulates bone growth. In cases of achondroplasia, the fgfr3 gene is too aggressive, negatively impacting bone growth. ...Read more

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Help please! is cancer caused by an extra chromosome or a lack of a chromosomes?

Help please! is cancer caused by an extra chromosome or a lack of a chromosomes?

Neither: cancer is caused by mutation in well defined genes that first lead to immortality and then the production of proteins that stimulate the cell to behave in an aggressive fashion. In Rous Sarcoma, the virus enters the Src gene causing a mutation giving rise to production of Src protein. Inhibition of Src gene causes sarcoma to revert to normal fibroblast. ...Read more

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Will a colorblind woman always have colorblind children? I know the cause is a mutation on the x-chromosome and a woman has to have the mutation on both her x’s. So that means all her children will have the colorblind gene. So will her children all be col

Will a colorblind woman always have colorblind children? I know the cause is a mutation on the x-chromosome and a woman has to have the mutation on both her x’s. So that means all her children will have the colorblind gene. So will her children all be col

Her : Her male children will be colorblind because all of her male children will have one of her x's with the colorblindness gene and a y from the dad that cannot cancel out the colorblindness gene on her x.

If she has children with a man who is not colorblind than her daughters will carry the gene, but not be colorblind themselves since they'll have a normal x from their dad to cancel out their mom's x with the colorblindness gene.

If she has children with a man who is colorblind, then her daughters will be colorblind also.

This is why colorblindness is much more common in men than in women.


Legal disclaimer: I am providing this general and basic information as a public service and my response to this question does not constitute a doctor-patient relationship. For any additional information, advice, or specific concerns, please speak with your own physician. The information provided is current as of the date of the answer entry. ...Read more

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Is chromosome deletion a probable cause of cerebral palsy?

Is chromosome deletion a probable cause of cerebral palsy?

No: By definition CP is a disorder of motion & posture caused by an injury to the developing brain from pregnancy to the 3rd birthday.Kids with chromosome deletions can have issues that mimic CP and some may suffer the same neurologic injury. The main culprits include infection, lack of blood flow or lack of oxygen leading to cell damage. ...Read more

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Can x-rays during early fetal development cause defects related to an extra chromosome?

Can x-rays during early fetal development cause defects related to an extra chromosome?

No: Chromosome defects exist in the fertilized egg after conception.You do not acquire it later during fetal development. ...Read more

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Is spina bifida caused by a spinal cord injury or chromosomal disorder?

Is spina bifida caused by a spinal cord injury or chromosomal disorder?

No one knows : There seems to be an interplay of genetic and environmental factors that cause this disease. Women who have had one child with spina bifida, or who are obese or diabetic have an increased chance of having a child with the problem. It is known that taking Folic Acid during the fertile years decreases the chance of having this problem. ...Read more