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Doctor insights on: Chromosomal Incompatibility In Pregnancy

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Rh incompatibility in second pregnancy; how does it happen?

Rh incompatibility in second pregnancy; how does it happen?

Sensitization: Mom is rh negative. Dad is rh positive. The baby, possibly both, are also rh positive. The first pregnancy will sensitize mom causing her to produce an rh antibody. This antibody will decrease over time. But with a second pregnancy, the memory cells cause tremendous antibody production. This antibody crosses through placenta and breakdown the red blood cells of the infant. ...Read more

Dr. Daniel Saurborn
4 Doctors shared insights

Pregnancy (Definition)

When your due date arrives, you will be more than ready to have your baby! Most women deliver the baby somewhere between 37 and 42 weeks. According to the American College of Obstetricians and Gynecologists, only 5% of babies arrive on the exact due date. Approximately 7% of babies are not delivered by 42 weeks, and when that happens, it is referred to ...Read more


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Why rhd incompatibility of the mother and fetus doesn't affect the present fetus but subsequent pregnancies?

Why rhd incompatibility of the mother and fetus doesn't affect the present fetus but subsequent pregnancies?

See below: The incompatibility occurs when the mother is exposed to the blood of the new baby. This usually occurs at delivery. The mother then makes antibodies to that "foreign substance" and this can adversely affect the next pregnancy as the mother's immune system will see it as a "foreign" body and want to get rid of it. This problem is usually treatable with an injection at the birth of the first child. ...Read more

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I'm 42. I'm miscarrying for the 3rd time. 1st were due to chromosome defects. What are my chances of having a successful pregnancy next time.

I'm 42. I'm miscarrying for the 3rd time. 1st were due to chromosome defects. What are my chances of having a successful pregnancy next time.

It depends.: You would only really be able to tell if you and your husband had genetic studies to see if you are carrying an abnormality. Even if both of you are normal, your risk is higher than average at age 42. For a more detailed response www. Askyourgynecologist. Org. ...Read more

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I had a previous down syn pregnancy, translocation type, im afraid all my babies will have DS? Is it possible that I have same chromosome translocation?

I had a previous down syn pregnancy, translocation type, im afraid all my babies will have DS? Is it possible that I have same chromosome translocation?

Possible: Yes it is possible you have a chromosomal abnormality. It's also possible that this was an isolated new event in that pregnancy. It would be an excellent idea to consult with a geneticist and/or a maternal-fetal medicine specialist prior to another conception to decide if you want or need to be tested and what all of your options are with another pregnancy. SO much info is available to you! ...Read more

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Is it possible to have normal quad test in the pregnancy if I have same chromosome translocation for chromosome 21?

Is it possible to have normal quad test in the pregnancy if I have same chromosome translocation for chromosome 21?

Yes but unlikely: There are such things as false negative tests. However, the quad test has a pretty good predictive value for negative results. ...Read more

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My pregnancy was terminated in 2nd month and karyotyping of foetus shows monosomy of chromosome 20.What are the chances of its recurrence.

My pregnancy was terminated in 2nd month and karyotyping of foetus shows monosomy of chromosome 20.What are the chances of its recurrence.

Unlikely: Based on your age it is unlikely. You are at higher risk than other women your age but yet it is still unlikely you would have another baby with the same genetic issue. ...Read more

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Is there any chromosome test that can be taken to find the cause of molar pregnancy? To prevent another molar?

Is there any chromosome test that can be taken to find the cause of molar pregnancy? To prevent another molar?

No cause: Apart from a few rare genetic syndromes, molar pregnancies "just happen." The two major types have two different chromosome types. Nothing you did and almost certainly nothing you inherited caused this disappointing outcome. Recurrences are rare. You can almost certainly have a healthy baby. ...Read more

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Can MRI effect the development of sperm cells or impact sperm in anyway, pre-pregnancy that could contribute to chromosomal translocation?

Can MRI effect the development of sperm cells or impact sperm in anyway, pre-pregnancy that could contribute to chromosomal translocation?

No: I am unaware of any evidence in the scientific literature that a standard diagnostic MRI has any adverse effect on sperm, developing sperm, or on a person who is pregnant or the fetus. The literature suggests that the strength of the mr field at diagnostic levels does not affect dna synthesis, cell cycle, or proliferation kinetics in a fetus. ...Read more

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Does slow rising hcg, if pregnancy turns out to be viable, indicate a chromosomal abnormality that could result in child with birth defects?

Does slow rising hcg, if pregnancy turns out to be viable, indicate a chromosomal abnormality that could result in child with birth defects?

Possibly: Healthy and viable pregnancies usually double the value of the HCG hormone every 48 hours. There are many tests that are used now to predict and/or define fetuses with chromosomal abnormalities. Because of your age these tests should be offered and considered. ...Read more

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Hx of 4 diagnosed chromosomal pregnancies in a row trisomy 22, 18, 13 & mono 21. I'm 39 yrs old. Is there hope of a normal pregnancy using my own eggs?

Hx of 4 diagnosed chromosomal pregnancies in a row trisomy 22, 18, 13 & mono 21. I'm 39 yrs old. Is there hope of a normal pregnancy using my own eggs?

Hope yes, but..: Remember, the ancient greeks said that hope was the last evil in pandora's box. Your history sounds horrible and I am very sorry. There is always a chance of normal pregnancy with your own eggs, however I would recommend genetic counseling and ivf with preimplantation genetic diagnosis in your case (or donor eggs). Take Folic Acid 1-5 mg daily and best of luck! ...Read more

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Can pcos cause poor egg quality? I've had 1 full-term pregnancy and 1 missed m/c due to chromosomal abnormalities. Thanks in advance for any insight.

Can pcos cause poor egg quality? I've had 1 full-term pregnancy and 1 missed m/c due to chromosomal abnormalities. Thanks in advance for any insight.

Shouldn't: The quality of the eggs is most directly related to their age - and they are as old as you are. As you age the possibility of genetic anomalies with each pregnancy increases. If you have had a pregnancy with a genetic anomaly, the the likelihood of a recurrence is also higher. ...Read more

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Does enlarged yolksac at the 7 weeks of pragnancy (7, 5mm) with HB 109 mean that will misscarry or if proceed will have a baby with chromosomal problem?

Does enlarged yolksac at the 7 weeks of pragnancy (7, 5mm) with HB 109 mean that will misscarry or if proceed will have a baby with chromosomal problem?

Not enough info: The most important piece of information here is that the baby had a heart beat. The risk of miscarriage goes down when a heart beat is seen. No predictions regarding outcome can be made. Follow up appointments will be needed. ...Read more

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Are virgin pregnancies rare?

Are virgin pregnancies rare?

Possible: Although unlikely, you can get pregnant without intercourse. If a man ejaculates just outside the vagina it's possible that the semen could travel far enough to cause a pregnancy. And there are many cases where a woman gets pregnant without intercousre and so, depending on the woman, could be considered a virgin birth if the woman in question had never had intercourse. ...Read more

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What are the ethics surrounding surrogate pregnancies?

What are the ethics surrounding surrogate pregnancies?

See answer: Ethics= society norms vs fair and just for all parties? Surrogate pregnancies or gestational carriers are used when the uterus of the biological mother is absent on unable to carry a pregnancy. Also when the mother has an illness that does not alloww her to carry a pregnancy. Pregnancy is a physical risk to the carrier so she should be at low risk and be aware of the psychological effect. ...Read more

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I'm wondering are unplanned pregnancies the most sacred kind?

I'm wondering are unplanned pregnancies the most sacred kind?

That is somewhat: Of a generalization. An unplanned pregnancy might be devasting for a young unwed woman without support. On the other hand, it could be a remarkable blessing for someone else. I believe that sacred may be in the eye / heart of the beholder. ...Read more

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Real pregnancy symptoms?

Several: There are several early signs of pregnancy including nausea +/- vomiting, breast tenderness, food cravings or aversions, tiredness, and increased urination. ...Read more

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Is sex safe in pregnancy?

Normally yes: The exception is when there is vaginal bleeding or if there is any suspicion of fluid leaking from the bag of waters. ...Read more

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How to get pregnancy fast?

How to get pregnancy fast?

No dollar stores: I would not rely on a dollar store pregnancy test. Some things in dollar stores are fine, but many things there are simply garbage. This has been shown in consumer reports numerous times. ...Read more

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Tell me diet in pregnancy?

Tell me diet in pregnancy?

Good healthy diet: A good healthy balanced diet combined with appropriate exercise. Talk w/your doctor and see a good registered dietitian. There should be some slow and steady weight gain during pregnancy that's natural. ...Read more

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Can I exercise in pregnancy?

Can I exercise in pregnancy?

Yes.: Absolutely yes! You can do whatever exercise you were oing priro to preganncy. You just don't want to escalate your activity or start something new. You should maintain your heartrate at 80% of your maximum. To calculate your max heartrate take 220 -age ; this number x. 8 should be 80% of your maximum. Of course activities with potential abdominal trauma should be avoided- kickboxing, water skiing. ...Read more

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What is ABO incompatibility?

What is ABO incompatibility?

Exposure to differen: Blood types. Typically refers to a baby having different blood type than mom. Therefore, there is prolonged breakdown of red blood cells, causing jaundice. This can occur in transfusions, where the wrong blood type is given. This is uncommon. ...Read more

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Is lithium safe in pregnancy?

Is lithium safe in pregnancy?

No.: Lithium is not safe during pregnancy. For one thing, it can cause cardiac/ heart defects in the baby (epstiens anomoly). Lithium has a narrow margin of safety ; therfore, the fluid shifts that occur during pregancy may effect lithium levels, putting both the mother and baby at risk. If a woman is on prescribed medications and becomes pregnant, she should notify her doctor immediately. ...Read more

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How do I care of my pregnancy?

How do I care of my pregnancy?

Prenatal care: Prenatal care is very important in order to achieve a healthy pregnancy and delivery. The key is to seek care early and to go often. Prenatal care is the only way to check the status of your pregnancy, receive important counseling, and have access to routine tests that all pregnant women should receive. Also, find the right doctor and building a good rapport with him or her is crucial. ...Read more

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How to loose pregnancy weight?

Diet and exercise: Wait until after you've finished breastfeeding, if you are. Then return to balanced restricted diet and increasing exercise -- the same as any other time in your life. You will also lose some just because you're no longer pregnant or nursing. You can do it, talk w/a good registered dietitian. ...Read more

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Is hot sauce bad for pregnancy?

Depends: Hot sauce per say is not something that will affect the outcome of pregnancy but may affect reflux symptoms with increased likelihood for gastritis. Plus pregnancy alone predisposes to acid reflux. ...Read more

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Is stretching bad for pregnancy?

Is stretching bad for pregnancy?

Physical: Activity to include stretching can help you to maintain your fitness. That's a positive. ...Read more