Doctor insights on:
Chromosomal Incompatibility In Pregnancy
Sensitization: Mom is rh negative. Dad is rh positive. The baby, possibly both, are also rh positive. The first pregnancy will sensitize mom causing her to produce an rh antibody. This antibody will decrease over time. But with a second pregnancy, the memory cells cause tremendous antibody production. This antibody crosses through placenta and breakdown the red blood cells of the infant. ...Read more
When your due date arrives, you will be more than ready to have your baby! Most women deliver the baby somewhere between 37 and 42 weeks. According to the American College of Obstetricians and Gynecologists, only 5% of babies arrive on the exact due date. Approximately 7% of babies are not delivered by 42 weeks, and when that happens, it is referred to ...Read more
Why rhd incompatibility of the mother and fetus doesn't affect the present fetus but subsequent pregnancies?
See below: The incompatibility occurs when the mother is exposed to the blood of the new baby. This usually occurs at delivery. The mother then makes antibodies to that "foreign substance" and this can adversely affect the next pregnancy as the mother's immune system will see it as a "foreign" body and want to get rid of it. This problem is usually treatable with an injection at the birth of the first child. ...Read more
I'm 42. I'm miscarrying for the 3rd time. 1st were due to chromosome defects. What are my chances of having a successful pregnancy next time.
It depends.: You would only really be able to tell if you and your husband had genetic studies to see if you are carrying an abnormality. Even if both of you are normal, your risk is higher than average at age 42. For a more detailed response www. Askyourgynecologist. Org. ...Read more
Wife pregnancy was terminated in 3rd month and karyotyping shows chromosomal analysis of poc is found abnormal 47, --+21. Is it will solve next time?
I had a previous down syn pregnancy, translocation type, im afraid all my babies will have DS? Is it possible that I have same chromosome translocation?
Possible: Yes it is possible you have a chromosomal abnormality. It's also possible that this was an isolated new event in that pregnancy. It would be an excellent idea to consult with a geneticist and/or a maternal-fetal medicine specialist prior to another conception to decide if you want or need to be tested and what all of your options are with another pregnancy. SO much info is available to you! ...Read more
Is it possible to have normal quad test in the pregnancy if I have same chromosome translocation for chromosome 21?
Yes but unlikely: There are such things as false negative tests. However, the quad test has a pretty good predictive value for negative results. ...Read more
My pregnancy was terminated in 2nd month and karyotyping of foetus shows monosomy of chromosome 20.What are the chances of its recurrence.
Unlikely: Based on your age it is unlikely. You are at higher risk than other women your age but yet it is still unlikely you would have another baby with the same genetic issue. ...Read more
Is there any chromosome test that can be taken to find the cause of molar pregnancy? To prevent another molar?
No cause: Apart from a few rare genetic syndromes, molar pregnancies "just happen." The two major types have two different chromosome types. Nothing you did and almost certainly nothing you inherited caused this disappointing outcome. Recurrences are rare. You can almost certainly have a healthy baby. ...Read more
With two prior pregnancy losses due to chromosomal abnormalities, how long should I try before seeing an infertility doctor?
Can MRI effect the development of sperm cells or impact sperm in anyway, pre-pregnancy that could contribute to chromosomal translocation?
No: I am unaware of any evidence in the scientific literature that a standard diagnostic MRI has any adverse effect on sperm, developing sperm, or on a person who is pregnant or the fetus. The literature suggests that the strength of the mr field at diagnostic levels does not affect dna synthesis, cell cycle, or proliferation kinetics in a fetus. ...Read more
Does slow rising hcg, if pregnancy turns out to be viable, indicate a chromosomal abnormality that could result in child with birth defects?
Hx of 4 diagnosed chromosomal pregnancies in a row trisomy 22, 18, 13 & mono 21. I'm 39 yrs old. Is there hope of a normal pregnancy using my own eggs?
Hope yes, but..: Remember, the ancient greeks said that hope was the last evil in pandora's box. Your history sounds horrible and I am very sorry. There is always a chance of normal pregnancy with your own eggs, however I would recommend genetic counseling and ivf with preimplantation genetic diagnosis in your case (or donor eggs). Take Folic Acid 1-5 mg daily and best of luck! ...Read more
Can pcos cause poor egg quality? I've had 1 full-term pregnancy and 1 missed m/c due to chromosomal abnormalities. Thanks in advance for any insight.
Shouldn't: The quality of the eggs is most directly related to their age - and they are as old as you are. As you age the possibility of genetic anomalies with each pregnancy increases. If you have had a pregnancy with a genetic anomaly, the the likelihood of a recurrence is also higher. ...Read more
Does enlarged yolksac at the 7 weeks of pragnancy (7, 5mm) with HB 109 mean that will misscarry or if proceed will have a baby with chromosomal problem?
Not enough info: The most important piece of information here is that the baby had a heart beat. The risk of miscarriage goes down when a heart beat is seen. No predictions regarding outcome can be made. Follow up appointments will be needed. ...Read more
Possible: Although unlikely, you can get pregnant without intercourse. If a man ejaculates just outside the vagina it's possible that the semen could travel far enough to cause a pregnancy. And there are many cases where a woman gets pregnant without intercousre and so, depending on the woman, could be considered a virgin birth if the woman in question had never had intercourse. ...Read more
See answer: Ethics= society norms vs fair and just for all parties? Surrogate pregnancies or gestational carriers are used when the uterus of the biological mother is absent on unable to carry a pregnancy. Also when the mother has an illness that does not alloww her to carry a pregnancy. Pregnancy is a physical risk to the carrier so she should be at low risk and be aware of the psychological effect. ...Read more
Yes.: Absolutely yes! You can do whatever exercise you were oing priro to preganncy. You just don't want to escalate your activity or start something new. You should maintain your heartrate at 80% of your maximum. To calculate your max heartrate take 220 -age ; this number x. 8 should be 80% of your maximum. Of course activities with potential abdominal trauma should be avoided- kickboxing, water skiing. ...Read more
No.: Lithium is not safe during pregnancy. For one thing, it can cause cardiac/ heart defects in the baby (epstiens anomoly). Lithium has a narrow margin of safety ; therfore, the fluid shifts that occur during pregancy may effect lithium levels, putting both the mother and baby at risk. If a woman is on prescribed medications and becomes pregnant, she should notify her doctor immediately. ...Read more
Prenatal care: Prenatal care is very important in order to achieve a healthy pregnancy and delivery. The key is to seek care early and to go often. Prenatal care is the only way to check the status of your pregnancy, receive important counseling, and have access to routine tests that all pregnant women should receive. Also, find the right doctor and building a good rapport with him or her is crucial. ...Read more
Diet and exercise: Wait until after you've finished breastfeeding, if you are. Then return to balanced restricted diet and increasing exercise -- the same as any other time in your life. You will also lose some just because you're no longer pregnant or nursing. You can do it, talk w/a good registered dietitian. ...Read more