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Chromophobe Renal Cell Carcinoma Eosinophilic Variant Grade 2
Is there a difference in the prognosis for typical and eosinophilic variant of chromophobe renal cancer?
Yes: Chromophobe renal cell carcinomas are classified into typical and eosinophilic variants depending on the predominant cell type. The evcrcc is not as common as the typical variant and is likely to be mistaken for oncocytoma because of the predominance of type i cells and hence the significance. The eosinophilic variant has been reported to have a better prognosis than typical variant. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
So far I've survived two surgeries having recurrent renal cell carcinoma. I've developed numerous lumps which I assumed were incisional hernias now th?
Full description? Q?: You already shared a complex past history. I'm glad you survived 2 surgeries for RCC. I'm not certain of what you are describing now - lumps in the location of the incision for the surgeries? - but if you have concerns about your recovery, you should either (1) talk to the surgeon who performed your (most recent) operation or (2) use HealthTap Prime to share pictures & go over a plan. Good Luck! ...Read more
Increased risk.: Smoking introduces many very carcinogenic compounds into the bloodstream, which is filtered by the kidney. These carcinogens, along with the decreased tissue oxygenation caused by smoking, is theorized to increase the risk of renal cell carcinoma. A meta-analysis of 24 studies (hunt, int j cancer 114:101-108, 2005) showed this significantly increased risk, & it is considered causal by the ussg. ...Read moreSee 1 more doctor answer
My brother has been diagnosed with metastatic renal cell carcinoma stage 4. Am i at risk of this disease . Is this cancer rare?
What r the chances of getting back renal cell carcinoma for an old male (63 yrs) after being cured by nephrectomy & taking nexavar (sorafenib) ?
Its possible. : When renal cell carcinoma metastasizes, it is most likely to spread to neighboring lymph nodes, the lungs, the liver, the bones, the adrenal glands, or the brain. Spread to the bone is often to the spine, but may be anywhere. Radiotherapy is often used in in cases of bone metastases, to reduce pain and lower the risk of pathologic fracture. ...Read more
My son had left kidney removed 2 yrs ago with renal cell carcinoma. He now has CHF not under control, is this serious?
Yes: Both conditions are serious.Get a more detailed answer ›
Possibly curable: Sunitinib, a new multitargeted tyrosine-kinase inhibitor (TKI), has shown high activity in patients with metastatic renal cell carcinoma (mRCC) and has demonstrated improvement in survival of those patients with metastatic disease. Sunitinib inhibits the vascular endothelial growth factor (VEGF) receptor and other tyrosine kinases, including the platelet-derived growth factor (PDGF) and c-kit receptor at nanomolar concentrations. ...Read more
Unusual but possible: Metastasis (spread) to the skin is uncommon for renal cell carcinoma. Lung is a much moe common site of spread. However, skin metastasis has been described. In fact, there are patients who were originally diagnosed solely through the biopsy of a suspicious skin lesion. Fortunately, unusual skin lesions are often accessible for biopsy which should decrease the uncertainty of diagnosis. ...Read moreSee 1 more doctor answer
Poor: Unfortunately even with chemo, stage IV renal cell has a short survival time. Some reasonably good chemo agents are coming available but present therapies may work for a while, then quit working. ...Read more
Varies: Even within stage 4, there are varying severities of disease. Survival can occasionally go beyond five years though most people will succumb in two or less years. ...Read more
Many facilities: There are many academic facilities that treat renal cell carcinoma. These include, ucsf, usc, city of hope, and ucla. ...Read more
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