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Doctor insights on: Chromophobe Renal Cell Carcinoma Eosinophilic Variant Grade 2

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Is there a difference in the prognosis for typical and eosinophilic variant of chromophobe renal cancer?

Is there a difference in the prognosis for typical and eosinophilic variant of chromophobe renal cancer?

Yes: Chromophobe renal cell carcinomas are classified into typical and eosinophilic variants depending on the predominant cell type. The evcrcc is not as common as the typical variant and is likely to be mistaken for oncocytoma because of the predominance of type i cells and hence the significance. The eosinophilic variant has been reported to have a better prognosis than typical variant. ...Read more

Dr. Barry Rosen
4,214 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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The size of my renal cell carcinoma is 7.2 x 7.2 x 8 cm what should I do?

The size of my renal cell carcinoma is 7.2 x 7.2 x 8 cm what should I do?

See a Urologist: You should see a Urologist and a Medical Oncologist. Much information is needed on imaging and rate of growth and other factors. This won't resolve using the internet. ...Read more

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What exactly does grade 1, 2, 3, 4 of the tumor mean in clear cell renal cell carcinoma?

What exactly does grade 1, 2, 3, 4 of the tumor mean in clear cell renal cell carcinoma?

How cells look: Grading refers to how closely the cancer cells resemble normal kidney cells. Cells that are more abnormal (ie higher grade) are associated with a worse prognosis. ...Read more

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Is renal cell carcinoma stage 4 an aggressive cancer?

Is renal cell carcinoma stage 4 an aggressive cancer?

Stage 4 : Stage 4 renal cell carcinoma usually means that the cancer has spread to other parts of the body. At this stage, the cancer is consider very aggressive. www.peedoc.com @drhtay. ...Read more

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Does renal cell carcinoma lead to chronic renal failure?

Does renal cell carcinoma lead to chronic renal failure?

Not necessarily: Only if both the kidneys have to be removed if cancer on both sides. If only one kidney or a part of kidney only is removed and the remaining kidney is healthy dialysis is not required. ...Read more

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How is tobacco smoking a risk factor for developing renal cell carcinoma?

How is tobacco smoking a risk factor for developing renal cell carcinoma?

Increased risk.: Smoking introduces many very carcinogenic compounds into the bloodstream, which is filtered by the kidney. These carcinogens, along with the decreased tissue oxygenation caused by smoking, is theorized to increase the risk of renal cell carcinoma. A meta-analysis of 24 studies (hunt, int j cancer 114:101-108, 2005) showed this significantly increased risk, & it is considered causal by the ussg. ...Read more

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What's life expectancy having renal cell carcinoma stage 3 a year after having kidney removed?

What's life expectancy having renal cell carcinoma stage 3 a year after having kidney removed?

About 5 years: The 5 year survival for stage 3 renal cell cancer is about 50%. This number may shift up or down a little because there are subcategoroes of stage 3 tumors whci will affect the prognosis. ...Read more

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What r the chances of getting back renal cell carcinoma for an old male (63 yrs) after being cured by nephrectomy & taking nexavar (sorafenib) ?

What r the chances of getting back renal cell carcinoma for an old male (63 yrs) after  being cured by nephrectomy & taking nexavar (sorafenib) ?

It depends: This is not an easy answer, because it depends upon the stage of your original tumor and your surgical pathology. I would ask this question of your urologist or oncologist, who know the specifics of your case. ...Read more

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Will renal cell carcinoma spread to the hip bone?

Will renal cell carcinoma spread to the hip bone?

Its possible. : When renal cell carcinoma metastasizes, it is most likely to spread to neighboring lymph nodes, the lungs, the liver, the bones, the adrenal glands, or the brain. Spread to the bone is often to the spine, but may be anywhere. Radiotherapy is often used in in cases of bone metastases, to reduce pain and lower the risk of pathologic fracture. ...Read more

Dr. Terence Chapman
288 doctors shared insights

Kidney Cancer (Definition)

Kidney cancer is a medical condition in which there is over proliferation of certain abnormal cell types found in the kidneys. Symptoms include abdominal mass, abdominal fullness or pain, blood in the urine, ...Read more