Doctor insights on:
Chorionic Villus Sampling
Yes and no: Chorionic villi sampling is a procedure where a small sample of cells from the placenta are removed, early in a pregnancy. A lab can determine if there are any extra or missing chromosomes, or large parts of a chromosome that are extra or missing. Other tests on chorionic villi can look for abnormalities in single genes, but no test can determine that a baby has no genetic abnormalities. ...Read more
Laboratory testing: Cvs sampling after 10 weeks of gestation can obtain tissue for testing. The tests usually done are chromosomal analysis or mutational analysis of a specific gene. ...Read more
I had an abortion when I was about 8 weeks pregnant. Just before the procedure I was asked if I would mind having another procedure performed on me called chorionic villi sampling (cvs). They said it was to train one of the doctors, who was being overseen
Can you tell me in karyotping a samplle from chorionic villi of amather was found to have xy sex chromosomes will this going l?
What?: Your question makes no sense to me. Please clarify. ...Read more
I cannot find a doctor who is willing to perform chorionic villi testing. Any ideas why not? What are risks?
Top caliber maternal: Fetal centers especially those with medical school affiliations should either perform chorionic villus sampling or be able to refer you to a center that does. There is a 1% risk of miscarriage & very minor risk of infection spotting pain or crampiing. Advantage over amniocentesis is that it can be performed earlier in pregnancy (10 -13 weeks after your last menstrual period). ...Read more
10-12 weeks: Chorionic villus sampling (cvs) obtains cells from the fetoplacenta for testing at 10-12 weeks of pregnancy, amniocentesis obtains fetal skin/urine cells at 16-18 weeks. Higher risks for miscarriage (2-3% for cvs, <0.5% or negligible for amnio) balance against the cvs advantage of testing before a women "shows, " preserving the privacy of pregnancy (testing). ...Read more
Genetic testing: Chorionic villous sampling represents one of the earliest available methods to accurately diagnose genetic abnormalities such as down's syndrome. While most, if not all, of these defects are not curable, it does give the patient the earliest opportunity to decide on whether to continue the pregnancy. ...Read more
MFMs: Maternal fetal medicine specialists usually perform cvs, although there are occasional doctors of other specialties who have been trained to do the procedure. Fellows, who are still in training, may perform the procedure under the supervision of the doctor who is teaching them. ...Read more
YES!!: You need a specialist, a maternal-fetal expert, also called a perinatologist to do this. Your OB can order it, but you need a specialist with experience & skills to minimize risks to your fetus. ...Read more
Placenta vs fluid: Cvs can usually be done earlier and involves obtaining placental tissue for chromosome analysis. This is done by needle biopsy either through the cervix or abdomen. Amniocentesis is obtaining amniotic fluid for testing also by needle aspiration. Both are done with ultrasound guidance, cvs slightly riskier with bleeding & cramping, both safe to do, both done by mfm docs. I hope that helps. ...Read more
Is it ok to skip the amnio or chorionic villus sampling procedure? Is it required to have it at my age of 38? . What will be the consequence for me?
Please discuss with: Your OB as this should be explained by your OB, I assume you will be getting an integrated screen which is an early test to r/o downs t-18, spinal bifida and now there are new blood tests to r/ o those problems like harmony and there are 3 others, so the majority of my pts do not get an amnio unless one of those tests is abnormal so u need to speak with your ob. ...Read more
Yes: Chorionic villus sampling (cvs) is done in the first trimester between 10-12 weeks. It has a slightly higher risk of miscarriage associated with it than an amniocentesis- which is usually done after 15 weeks- because it is performed earlier in the pregnancy. Blood tests and a nuchal translucency ultrasound are noninvasive genetic screening options. ...Read more
Looks at chomosomes: Chorionic villus sampling enables a doctor to remove a small sample of the tissue that surrounds the early sac of pregnancy. This, then, allows the study of the chomosomes - for early diagnosis of conditions such as Down syndrome (an extra chromosome #21). It is done with ultrasound guidance at roughly 11 weeks of pregnancy. Amniocentesis is a procedure done later in pregnancy for the same reason. ...Read more
What are amniocentesis, chorionic villus sampling and blood/saliva test screening used for? Abortions?
Prenatal diagnosis: Cvs and amniocentesis are used to discover chromosomal abnormalities in the fetus. They are also used to diagnose genetic diseases, such as cystic fibrosis, that some people are at risk for. Blood and saliva screening tests are used to find out if parents are at risk for a baby with certain genetic diseases. ...Read more
My pregnant qife 34 years old, blood test came out trisomy21 1:14. Doctor ordered chorionic sample. What is the chance of my baby?
Trisomy 21: Trisomy 21 or Down's Syndrome is the concern for your girlfriend and you. The MD wants to get a sample of the chorion (pregnancy membrane) which has the genetic composition of the fetus and can then give you an accurate answer about the status of the baby. There may be some challenges ahead and decisions to make if this is confirmed. ...Read more
Safety of chorionic sampling vs. Amniocentesis for prenatal diagnosis of chromosomal abnormalities?
Risks: The risk of pregnancy loss has been looked at in four randomized studies of cvs vs. Amniocentesis. All four studies show that both procedures have about the same risk of pregnancy loss. About 1 in 1600. Another cvs study showed that losses in a group of women who had the procedure were equal to losses in a group of women who didn't have the procedure. A loss may not be related to the procedure. ...Read more
Invasion by germ: The chorion is the outermost layer of membranes surrounding a fetus in the womb. The term "chorionic infection" implies that germs have ascended from the female genital tract and invaded this tissue. This can be dangerous to the health of the fetus. ...Read more