Doctor insights on:
Chorionic Villus Sampling
Yes and no: Chorionic villi sampling is a procedure where a small sample of cells from the placenta are removed, early in a pregnancy. A lab can determine if there are any extra or missing chromosomes, or large parts of a chromosome that are extra or missing. Other tests on chorionic villi can look for abnormalities in single genes, but no test can determine that a baby has no genetic abnormalities. ...Read more
10-12 weeks: Chorionic villus sampling (cvs) obtains cells from the fetoplacenta for testing at 10-12 weeks of pregnancy, amniocentesis obtains fetal skin/urine cells at 16-18 weeks. Higher risks for miscarriage (2-3% for cvs, <0.5% or negligible for amnio) balance against the cvs advantage of testing before a women "shows, " preserving the privacy of pregnancy (testing). ...Read more
What are amniocentesis, chorionic villus sampling and blood/saliva test screening used for? Abortions?
Prenatal diagnosis: Cvs and amniocentesis are used to discover chromosomal abnormalities in the fetus. They are also used to diagnose genetic diseases, such as cystic fibrosis, that some people are at risk for. Blood and saliva screening tests are used to find out if parents are at risk for a baby with certain genetic diseases. ...Read moreSee 1 more doctor answer
Safety of chorionic sampling vs. Amniocentesis for prenatal diagnosis of chromosomal abnormalities?
Risks: The risk of pregnancy loss has been looked at in four randomized studies of cvs vs. Amniocentesis. All four studies show that both procedures have about the same risk of pregnancy loss. About 1 in 1600. Another cvs study showed that losses in a group of women who had the procedure were equal to losses in a group of women who didn't have the procedure. A loss may not be related to the procedure. ...Read more
MFMs: Maternal fetal medicine specialists usually perform cvs, although there are occasional doctors of other specialties who have been trained to do the procedure. Fellows, who are still in training, may perform the procedure under the supervision of the doctor who is teaching them. ...Read more
Genetic testing: Chorionic villous sampling represents one of the earliest available methods to accurately diagnose genetic abnormalities such as down's syndrome. While most, if not all, of these defects are not curable, it does give the patient the earliest opportunity to decide on whether to continue the pregnancy. ...Read more
Placenta vs fluid: Cvs can usually be done earlier and involves obtaining placental tissue for chromosome analysis. This is done by needle biopsy either through the cervix or abdomen. Amniocentesis is obtaining amniotic fluid for testing also by needle aspiration. Both are done with ultrasound guidance, cvs slightly riskier with bleeding & cramping, both safe to do, both done by mfm docs. I hope that helps. ...Read moreSee 1 more doctor answer
Looks at chomosomes: Chorionic villus sampling enables a doctor to remove a small sample of the tissue that surrounds the early sac of pregnancy. This, then, allows the study of the chomosomes - for early diagnosis of conditions such as down syndrome (an extra chromosome #21). It is done with ultrasound guidance at roughly 11 weeks of pregnancy. Amniocentesis is a procedure done later in pregnancy for the same reason. ...Read more
Beta HCG,Serum by CLIA :Increased in Pregnancy,Gestational trophoblastic tumors, benign or malignant.It means?
Histological section shows mainly decidualised endometrial tissue with hyperplastic glandular component
specimen: uterine evacuation?
Hyperplasia: The sample you describe is suggestive of overgrowth of tissue in the uterus due to irregular menstrual cycles. It is seen in women who go for > 6 months without bleeding and suggests overstimulation due to estrogen effect. If left untreated, it could lead to endometrial cancer. Still, it is very slow growing but needs to be monitored. ...Read more
Hard to be certain: Ultrasound is never 100%, but several findings are suspicious for endometrial hyperplasia or even cancer. For instance, if your lining is excessively thick for your age or if there is a suspicious mass seen within the uterine cavity on the sonogram, hyperplasia or cancer may be present. However, other findings can cause similar images on sonogram. Also, diagnosis can only be made with a biopsy. ...Read moreSee 1 more doctor answer
Biopsy: Transvaginal ultrasound is not designed to detect endocervical cancer. An early lesion may not produce enough structural change to be picked up ultrasound. If there is any reason to suspect endocervical cancer, curettings, or biopsy of the canal should be tested by a pathologist. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more
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