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Doctor insights on: Chondrocyte

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Does estrogen affect the spinal chondrocytes? (not long bone chondrocytes)

Does estrogen affect the spinal chondrocytes? (not long bone chondrocytes)

No: Estrogen does not have an effect on chondrocytes to my knowledge. But this is a very specific basic medical science question without much clinical relavence. ...Read more

Dr. Allen Lu Dr. Lu
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Can stem cells rebuild cartilege?

Dr. Allen Lu Dr. Lu
2 doctors agreed:
Can stem cells rebuild cartilege?

Yes, but!: Many types of stem cells have been made to form cartilage (including stem cells from fat, marrow, amnion, blood). I have even personally done much research on this. However, the problem is that we have no good way of placing the cartilage back into the knee (or other joint) and keep it in place while the body heals. There are encouraging trials, but no definitive solutions yet. ...Read more

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What is patellar chondro malatia?

What is patellar chondro malatia?

Knee pain: It's the most common knee pain that we see in the clinic. Many athletes and walkers get it and get concerned that it might be something more serious. Also many of the first time marathon runners get it as well. The best treatment for it is physical therapy including some easy stretches and warm-up before and after exercise as well as anti-inflammatories (natural and chemical). ...Read more

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MRI Grade 2/3 chrondromalacia glenohumeral joint w/ high grade cartilage loss, Bone marrow edema of the humeral head, mod. Glenohumeral effusion?

MRI Grade 2/3 chrondromalacia glenohumeral joint w/ high grade cartilage loss,  Bone marrow edema of the humeral head, mod. Glenohumeral effusion?

Degenerative changes: This constellation is typical of osteoarthritic degenerative changes. The cause is non-specific and can be related to prior shoulder trauma or just a life time of heavy use. ...Read more

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What exactly is hypocellular bone marrow?

What exactly is hypocellular bone marrow?

Not enough cells: The bone marrow is the factory of the blood -- all blood cells begin life there. The "normal" amount of cells decreases with age, so we estimate normal as 100 - (age) +/- 20%. So, if a 50 year old has 50% of the space in the bone marrow filled with cells, we say this is normal. If it were 25%, it would be hypocellular. However, if a 90 year old had 25% cellularity, it is probably normal. Helps? ...Read more

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Do bone marrow aspirations mean leukemia?

Do bone marrow aspirations  mean leukemia?

No: We do them for several reasons including evaluation for an abnormal cbc. Sometimes we are concerned about leukemia but the other reasons include the following: anemia, low platelets, staging of lymphoma, monitoring therapy. Hope this helps. ...Read more

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Does embryonic stem cells came from the bone marrow?

Does embryonic stem cells came from the bone marrow?

Stem cells: There are many types of stem cells that reside in the bone marrow. They technically aren't "embryonic" stem cells, since those by definition are derived from an embryo. The stem cells that exist in your bone marrow, however, share many of the characteristics of embryonic stem cells. ...Read more

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MRI -Marrow edema, chondral thinning, elongated osteochondral lesion (6x17mm) lateral talar dome.increased signal distal syndesmosis -- need surgery?

MRI -Marrow edema, chondral thinning, elongated osteochondral lesion (6x17mm) lateral talar dome.increased signal distal syndesmosis -- need surgery?

Talar Dome Lesion: Kolleen, you have a large lesion off soft bone inside your ankle. Surgery can be an option, but attempting to create a pain free environment (from boot to just activity restrictions), contrast bathing nightly to increase circulation, Exogen bone stimulator for 9 months, repeat MRI in 6 months to see if improvement is being made, and other treatments available may avoid surgery. Dr Blake ...Read more

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What is bone marrow edema?

What is bone marrow edema?

No such thing!: I would ignore it. it does not mean anything. I would not be concerned about this as it is a nonentity! ...Read more

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Reticulocytes low, pancytopenia, & bone marrow destruction indicates which type of anemia?

Reticulocytes low, pancytopenia, & bone marrow destruction indicates which type of anemia?

Complex problem: It appears that your bone marrow is not making new blood, so you have anemia due to the failure of production. If you have pancytopenia then the problem is much more than anemia alone. Such situation are either due to leukemia or preleukemic conditions like Myelodysplastic syndrome(MDS). You need a blood specialist to help you sort it out and guide you further. ...Read more

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What is nonclonal mast cell activation disorder?

What is nonclonal mast cell activation disorder?

Newly characterized: It's a mimic for disorders caused by a neoplastic clone of mast cells. This is hematology subspecialist stuff and i would much rather have this than one of the clonal forms. http://www.ncbi.nlm.nih.gov/pubmed/23212667. ...Read more

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Knee pain took an MRI result says medial femoral chondromalacia osteophyte formation irregular denudation of articular cartilage what is d treatment?

Knee pain took an MRI result says medial femoral chondromalacia osteophyte formation irregular denudation of articular cartilage what is d treatment?

This means arthritis: This means some degree of degenerative arthritis various options are available but none will cure the problem discuss with an orthopedic surgeon. ...Read more

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What's allogeneic bone marrow transplantation like?

What's allogeneic bone marrow transplantation like?

BMT from a donor: Allogeneic bone marrow transplantation (bmt) uses another person as the source of stem cells (bone marrow) as opposed to autologous bmt which uses the patient's own cells (usually frozen). Syngeneic bmt uses an identical twin for the donor. Allogeneic donors can be relatives (usually siblings) or totally unrelated. For more info on bmt check out: http://marrow.Org/. ...Read more

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Horizontal Tear of the Posterior Horn of the Medial Menistic &Suprapatellar joint Effusion ,Articular Cartilage Loss & 3MM Medial Popliteal Cyst means

Horizontal Tear of the Posterior Horn of the Medial Menistic &Suprapatellar joint Effusion ,Articular Cartilage Loss & 3MM Medial Popliteal Cyst means

Arthritis and tear: The cartilage loss is similar to saying you have degenerative arthritis setting up in your knee. The meniscus is a cartilage cushion present in your knee, there is one present medically and one lateral, and you have a tear in one as well. I would go through your MRI with an orthopedic surgeon to discuss options. ...Read more

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MRI result showed sub articular marrow oedema and bony erosions, what is this?

MRI result showed sub articular marrow oedema and bony erosions, what is this?

Harrowed Marrow: It means there's been a lot of stress and/or inflammation in that joint.I bet it hurts.What happens next is up to you and your doctor.Ask him/her to go over the MRI with you and discuss all of your options(there are many).In the meantime don't fret too much,they've come up with a lot of tricks to take care of joints.Just make sure you trust their opinions.Any doubt? Get a 2nd opinion. ...Read more

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What is bone marrow?

What is bone marrow?

Home of blood cells: The cells in your blood are born and reach maturity in the bone marrow. This is the very protected space in the middle of your large bones like your arms, legs, hips and back. Once the cells are mature, they are released into the blood stream where they travel throughout the body preventing infection (granulocytes, lymphocytes), supply oxygen (red cells) and prevent bleeding (platelets). ...Read more

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Bone cysts versus bone spurs?

Bone  cysts versus bone spurs?

Inside bone/tendons.: Bone cysts r contained inside the bone, any where from simple benign @ malignant and need watching. Spurs r at the edges of the bone as in arthritis, or in response 2 tendinitis where a tendon attaches. As patellar tendinitis or where ligaments attach as in heel spurs ( planter fasciitis). Treatments r different 4 each & multiple 4 each. B followed & rx'd by an orthopedic surgeon. ...Read more