Top
40
Doctor insights on: Cholinergic

Share

Cholinergic (Overview)

Cholinergic typically refers to acetylcholine in the neurological sense. The parasympathetic nervous system, which uses acetylcholine almost exclusively to send its messages, is said to be almost entirely cholinergic. Neuromuscular junctions, preganglionic neurons of the sympathetic nervous system, the basal forebrain, and brain stem complexes are also cholinergic.


1

1
What is the definition or description of: cholinergic?

What is the definition or description of: cholinergic?

See below: Cholinergic typically refers to acetylcholine in the neurological sense. The parasympathetic nervous system, which uses acetylcholine almost exclusively to send its messages, is said to be almost entirely cholinergic. Neuromuscular junctions, preganglionic neurons of the sympathetic nervous system, the basal forebrain, and brain stem complexes are also cholinergic. ...Read more

Cholinergic (Overview)

Cholinergic typically refers to acetylcholine in the neurological sense. The parasympathetic nervous system, which uses acetylcholine almost exclusively to send its messages, is said to be almost entirely cholinergic. Neuromuscular junctions, preganglionic neurons of the sympathetic nervous system, the basal forebrain, and brain stem complexes are also cholinergic.


3

3
What are the things should I follow and avoid for cholinergic utricaria?

What are the things should I follow and avoid for cholinergic utricaria?

Use antihistamine: Zyrtec.........cetirizine 10mg is best. Begin at 1 a day. If needed, can try 2 or 3 a day. Watch out because about 10% of people get sleepy with this and will change to loratadine or fexofenadine. ...Read more

4

4
Is cholinergic urtciaria usually seasonal? Does it go away in the colder seasons?

Is cholinergic urtciaria usually seasonal? Does it go away in the colder seasons?

Not necessarily: Cholinergic urticaria can flare in hot humid weather, but can also flare with exercise, as well as stress - either mental or physical stress. ...Read more

5

5
How to releive from itching and prickling due to cholinergic utricaria? Kindly help me. Itching is torturing me a lot.

How to releive from itching and prickling due to cholinergic utricaria? Kindly help me. Itching is torturing me a lot.

Cholinergic urticari: At times can be difficult to control, at any rate you need to avoid triggers that would induce sweating, as much as you can e.g. exercise in warm weather, spicy foods, hot baths, . etc. Then you need to take the prescribed medications on regular basis not only as needed, medications can be antihistamines (different forms), or combination medicines. Kindly follow up with an experienced dermatologist ...Read more

6

6
Is Cholinergic Urticaria dangerous?

Is Cholinergic Urticaria dangerous?

No: Cholinergic urticaria (CU) is one of the physical urticaria (commonly referred to as hives), which is provoked during sweating events. Sometimes, this can be called a "heat rash." by some doctors. This is not a dangerous condition. ...Read more

7

7
How to get cholinergic urticaria disease?

Urticaria: I assume you are asking for the cause of it, it is secondary to unstable mast cells in the skin and are triggered by contact with water. It is benign but annoying. ...Read more

8

8
How can we get cholinergic urticaria disease?

How can we get cholinergic urticaria disease?

Cholinergic Hives: Cholinergic urticaria (hives) account for around 30% of all cases of physical urticaria and around 5% of all cases of chronic hives. Onset is usually around the 2nd or 3rd decade of life and has been shown to be more common in males. Triggers include increase in core body temperature and include common triggers like exercise with sweating, strong emotions, and bathing in hot water. See Allergist. ...Read more

9

9
How can I deal with my cholinergic urticaria?

How can I deal with my cholinergic urticaria?

By taking: An anticholinergic such as Ipratropium. Only your Doctor can decide if these kinds of medicines are appropriate for you. ...Read more

10

10
Can you tell me how could we get cholinergic urticaria disease?

Can you tell me how could we get cholinergic urticaria disease?

Cholinergic Hives: Cholinergic urticaria (hives) account for around 30% of all cases of physical urticaria and around 5% of all cases of chronic hives. Onset is usually around the 2nd or 3rd decade of life and has been shown to be more common in males. Triggers include increase in core body temperature and include common triggers like exercise with sweating, strong emotions, and bathing in hot water. See Allergist. ...Read more

11

11
Does having more % body fat worsen symptoms of cholinergic urticaria?

Yes: It'll itch in your folds. There are many, far better reasons to trim down, as well. Hit the gym, get fitness-focused friends, get used to the idea of eating only to satisfy real genuine hunger, and you'll have the body that a 22 year old guy should. You can do it. Best wishes. ...Read more

12

12
Is it possible to have cholinergic urticaria without producing hives?

Is it possible to have cholinergic urticaria without producing hives?

Yes: Actually, by definition, no, but I have had patients with every aspect of the disease without the hives, so I just treat it is a variant. ...Read more

13

13
Why are adrenergic blockers used to treat hypertension instead of cholinergics?

Why are adrenergic blockers used to treat hypertension instead of cholinergics?

Raises Blood Pressur: Because they do not reduce Blood Pressure like the Adrenergic Alpha and Beta Blockers
Anticholinergics are actually contraindicated in Hypertension as these drugs can raise the Blood Pressure ...Read more

14

14
Help! Need to know if there's any one who can help me about cholinergic urticaria?

Help! Need to know if there's any one who can help me about cholinergic urticaria?

See an allergist: Cholinergic urticaria, or "heat hives", is one of several types of physical urticarias. It has a unique appearance, being small bumps that itch associated with increased body temperature, and can be confused with exercise induced hives. Be sure to rule out early exercise induced anaphylaxis ("shock"). There are a number of good allergists in Chicagoland, check www. Aaaai. Org ...Read more

15

15
Which drug is best to stop clozapine and to reduce the withdrawal cholinergic rebound?

See ur Doctor: Stopping Clozapine is a Major decision in any treatment plan, it is taken very seriously by the treating physician and all risks and benefits are weighed carefully, it cant be done over the net, you have to see your prescribing physician and discuss with him the issue. Good luck and feel better ...Read more

16

16
Do you know which drug is best to stop clozapine, and to reduce withdrawal cholinergic rebound?

Do you know which drug is best to stop clozapine, and to reduce withdrawal cholinergic rebound?

Requires expert care: Withdrawing from clozapine may come with *many* potential consequences. I hope you have someone with sufficient expertise to help with the process.
The anticholinergic withdrawal syndrome (AWS) is often described as flu-like malaise. Brain-permable anticholinergic meds like benztropine (Cogentin) or scopolamine would be reasonable treatments for AWS.
This should be undertaken w a psychiatrist. ...Read more

17

17
What are some apparent signs that cholinergic urticaria going away? It's odd that I got this when I barely know any family members with ths.

What are some apparent signs that cholinergic urticaria going away? It's odd that I got this when I barely know any family members with ths.

When no more symptom: When you no longer note the symptoms. As far as I know, this is not an inherited disorder. Since this is induced by increase in core body temperature and stress, perhaps once the stress is over or moving to an area with cooler climate would improve the problem as well ...Read more

18

18
Is it technically correct to categorize cholinergic urticaria as a physical hive? I am uncertain because It is triggered from things like emotions.

Yes: emotions can precipitate swearing, and sweat is the problem rather, not the heat, hope the treatment works, and hope that you have spontaneous recovery soon ...Read more

19

19
What is the treatment for chronic cholinergic hives?

What is the treatment for chronic cholinergic hives?

Stay cool.: If you have cholinergic urticariia you get tiny hives that grow & merge when skin temperature increases. This occurs with hot showers, hot weather, exercise & fever. Cooler showers, air conditioning, & tylenol (acetaminophen) for fevers will help. All antihistamines are useful but the best is thought to be periactin (cyproheptidine). In difficult cases I add Neurontin (gabapentin). Be prepared to be drowsy. ...Read more

20

20
Daughter had something like cholinergic urticaria? What is that?

Daughter had something like cholinergic urticaria? What is that?

Heat Assoc Hives: Cholinergic urticaria is a type of hives brought on by heat inducing stimuli. Meaning, it causes small 2-3 mm hive-like bumps symmetrically on the body after something is done to increase the body's core temperature. Exercise, hot weather, spicy foods, and alcohol can all bring on an episode. It usually happens in young people, and is rare in the elderly. The hives are very itchy. ...Read more

22

22
Do you know if acetylcholine is considered an agonist for the cholinergic receptors?

Do you know if acetylcholine is considered an agonist for the cholinergic receptors?

Terminology: Why are cholinergic receptors called cholinergic receptors? You can apply acetyl choline to cholinergic receptors and see the physiologic changes. ...Read more

23

23
Doctors don't seem to know a lot about chronic cholinergic hives. Does reducing chronic stress make them disappear spontaneously in some cases?

Doctors don't seem to know a lot about chronic cholinergic hives. Does reducing chronic stress make them disappear spontaneously in some cases?

Cholinergic Hives: There is no cure for cholinergic urticaria, and treatment options are often limited. Some common treatments include taking antihistamines (such a allegra, (fexofenadine) zyrtec, or stronger ones), avoiding known triggers (such as hot weather, physical activity, and spicy foods), corticosteriods (only for extreme cases), anabolic steroids, uvb therapy, sweat/exercise therapy, diet changes. ...Read more

24

24
I have cholinergic urticaria. Histamines don't work. With every single physicle exercise the symptoms got worse. What should I do? Please help me

I have cholinergic urticaria. Histamines don't work. With every single physicle exercise the symptoms got worse. What should I do? Please help me

Immunologist: I would recommend you see a board certified immunologist, they probably would not be they allergy shot type bu a clinical immunologist. It is your mast cells releasing histamine, possibly a drug that is a mast smell stabilizer would help you. ...Read more

25

25
Allegra (fexofenadine hydrochloride 120 mg)at morning and levocet 5mg at night for 60 days. How effective these medicines for cholinergic utricaria?

Mildly helpful: First, make sure you aren't having early anaphylaxis (generalized shock). If only heat hives (small, pinpoint) my experience is that cetirizine (or levocetirizine) combined with ranitidine (H2 antihistamine), either once or twice a day might work a little better. If not, you'll need stronger antihistamines like hydroxyzine (don't drive or operate machinery); at that point get seen by a doctor. ...Read more

26

26
Is dermatografism and cholinergic urticaria an allergy condition?

Is dermatografism and cholinergic urticaria an allergy condition?

Not really: These conditions can overlap or can be separate entities that involve hives. The immune cells that release histamine and other mediators that promote hives are triggered by non-allergic triggers (mechanical disruption of the skin or by heat, respectively). Thus, it is allergy in the sense that experts in understanding this part of the immune system treat these conditions, but no allergic antibody ...Read more

28

28
Can someone have cholinergic urticaria without having any rashes or hives on his body??

Terminology: Urticaria is an other way to say hives. So you can not have urticaria without hives.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex, if you have sex. ...Read more

30

30
How likely is anaphylaxis from cholinergic urticaria? Safe to exercise with this condtion?

How likely is anaphylaxis from cholinergic urticaria? Safe to exercise with this condtion?

Very unlikely: Cholinergic urticaria can be exacerbated by exercise, heat and stress but will not lead to anaphylaxis. You can take an antihistamine prior to exercise to reduce itching and hives ...Read more

31

31
Are there any documentation on being cured from cholinergic urticaria through placebo effect?

Are there any documentation on being cured from cholinergic urticaria through placebo effect?

Sure: All the patients who had that particular disorder, and had their disorder eventually go away on its own, without using any proven treatment or medication causing the disorder to go away, can say they were cured through placebo effect or simply said, they cured themselves. ...Read more

32

32
I have eczema but recently, I have cholinergic urticaria too. Can both aggravate each other? Thanks

I have eczema but recently, I have cholinergic urticaria too. Can both aggravate each other? Thanks

Not Benadryl!!!: Unless you need a sleeping pill, throw out the Benadryl. Before exercise take an antihistamine. Allegra, Zyrtec, Claritin. Generics work the same but cost less. Zyrtec [cetirizine] is most effective but about 1 person in 10 is sedated by it. The dose can be 1 to 4 pills, determined by experience. No antihistamine helps eczema itch. They are for urticaria. Cortisone creams, prescriptions, are for e ...Read more

33

33
Can someone have cholinergic urticaria without any rashes on his body? And if yes, does it have any cure?

Can someone have cholinergic urticaria without any rashes on his body? And if yes, does it have any cure?

No but: By definition, you need to have urticaria to have this condition. Having said that I can envision someone with a less severe form of itching from the same mechanism for which antihistamine usually works. You are however more likely to have dry skin for which twice daily application of moisture with at least one <3 mins after bathing may be effective. No cure but some people do recover from it. ...Read more

34

34
Is stinging a normal symptom for cholinergic urticaria when you get warm to hot? It is very painful at its worst.

Is stinging a normal symptom for cholinergic urticaria when you get warm to hot? It is very painful at its worst.

No: cholinergic urticaria shows up as small itchy bumps and not painful ones usually subsiding within hours. Need to see a dermatologist to find out the cause for your problem especially if there are painful blisters present. ...Read more

35

35
Have unbearable stinging and itching from Cholinergic hives. If I endure it when lifting weights, will I be at risk of severe allergic rxn?

Not usually: Take an antihistamine about 1-2 hrs before strenuous exertion should usually control the hives. Although a may also experience shortness of breath or GI symptoms with cholinergic urticaria, most people don't have these issues. This is not a life-threatening problem. ...Read more

37

37
Have cholinergic urticaria n its spoilled everything im not able to do minor things cuz it attacks. I got to give up exercise. No antihistamine worked?

Urticaria: Urticaria can come from local irritants allergens or physical and environmental reasons. It sounds like you have a more severe case and should see an allergist for more aggressive evaluation and treatment. Steroids, finding what may be a trigger and avoiding that and time may all be helpful. Have your doctor refer you to an allergist, and don't give up, most peoples responses wain over time. ...Read more

38

38
How do I get rid of cholinergic urticaria caused by heat?

Avoid heat: The above answer may seem flippant but this is exactly what you can do to avoid it. Many people however have found that taking an antihistamine 1-2 hrs prior to exposure to heat may keep it under control. ...Read more

40

40
Does loratadine work for prickly heat cholinergic urticaria?

Urticaria: Loratadine can work for some people. Also I find that some patients respond well to zyrtec (cetirizine) (ceterizine) daily. Both are available over the counter. ...Read more