Doctor insights on:
This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more
Several: They depend on cause and age of patient. In preterm infants, it is frequently from prolonged use of TPN and late start of feeds. Majority resolve. In some cases it can cause gall bladder sludge, gall stones or inflammation/infection of the plumbing system of the liver (cholangitis). In extreme cases, these patients can develop cirrhosis and chronic liver failure and may need liver transplant. ...Read moreSee 1 more doctor answer
Depends on age: Tpn is certainly toxic to the liver over time and eventually will result in liver cirrhosis from cholestatic disease. The exact etiology is unclear but the presence of lipids (fats) and the type of lipids in the TPN contributes to the problem. The immature liver of an infant or child develops complications faster than an adult liver. We try to lower lipid levels in TPN to minimize liver damage. ...Read moreSee 2 more doctor answers
Doubt it: There is not much evidence of liver damage by glucosamine. According to mayo clinic : one patient developed liver inflammation (acute cholestatic hepatitis) after taking glucosamine forte. Review this good article. http://www.mayoclinic.com/health/glucosamine/ns_patient-glucosamine/dsection=safety. ...Read moreSee 1 more doctor answer
Need more info: Impossible to answer accurately your question with the information provided. Data needed--are you reporting high lft's (cholestatic or hepatocellular) or a lesion? 1) how big is the lesion? 2) how long has it been there? 3) is it enlarging, ;at what rate? 4) cystic or solid? 5) is it causing symptoms? 6) do you have underlying liver disease? 7) has a tissue diagnosis (biopsy) been pursued? ...Read moreSee 1 more doctor answer
Yes. Not common.: Yes. Multiple myeloma can effect any organ. However, liver involvement is not common. Myeloma generally involves the bones predominantly; however there are reports of nearly every organ being involved in including the brain. Liver involvement by any cancer can make some types of chemotherapy (that is processed by the liver) more difficult to give. ...Read moreSee 1 more doctor answer
Conjugation: There is also evidence that hypothyroidism may directly affect the liver structure or function. Hypothyroidism has been associated in a few case reports with cholestatic jaundice attributed to reduced bilirubin and bile excretion. Recent studies have shown that the hepatic abnormalities associated with hypothyroidism can be reversible with thyroxine replacement with no residual damage. ...Read more
- Talk to a doctor live online for free
- Cholestatic liver disease
- Types cholestatic liver disease
- Cholestatic liver disease treatment
- Ask a doctor a question free online
- Cholestatic liver disease symptoms
- What is a liver laceration?
- How long will you live with stage 4 liver cancer?
- How can you reduce sgpt level and improve fatty liver?
- Talk to a gastroenterologist online