Doctor insights on:
Cholestasis Risk Factors
Weight/Family Hist.: Obesity is a major risk for any diabetes. The other factor is genetics. There are many women of asian descent who have a normal weight (and body mass index), but develop gestational or regular diabetes. Obesity is one that people can modify though. ...Read moreSee 1 more doctor answer
Threats to baby, mom: Risk factors include conditions that might affect the health of the fetus and/or pregnant woman. Those include higher chance for birth defects, >1 baby, prior preterm birth, diabetes, history of eclampsia. Many women at high risk for pregnancy complications have healthy babies, but they probably saw perinatologists, had extra testing or imaging, or underwent treatments or delivery with nicu aware. ...Read moreSee 1 more doctor answer
Variable: Many people may have gallstones and have no symptoms at all. Some people will get upper abdominal pressure, bloating, discomfort, nausea or vomiting. Eating fatty foods may make more discomfort. Vomiting, inability to eat are common. Serious infections sometimes can occur, and sometimes the gallstone can cause bile duct blockage with marked pain, vomiting, jaundice, and sometimes pancreatitis. ...Read more
Atherosclerosis: Depends on one's personal risks smoking, obesity, hypertension, hyperlipemia, diabetes , family history. Simply, one blocks the feeding artery to part of the heart muscle and low flow, or no flow causes ischemia which cause death of the heart cells, which is a heart attack! myocardial infarction is the medical term.Ekg and lab tests show the damage. ...Read more
Many: Diabetes can affect the developing baby throughout the pregnancy. In early pregnancy, a mother's diabetes can result in birth defects and an increased rate of miscarriage. Many of the birth defects that occur affect major organs such as the brain and heart. During the 2nd & 3rd trimester, a mother's diabetes can lead to over-nutrition & excess growth of the baby. ...Read moreSee 2 more doctor answers
Multifactorial: There are a number of medical conditions preexisting in the mother that can increase risk of iugr, including hypertension, lupus, kidney disease, and sickle cell; fetal conditions such as abnormal chromosomes; twins or more; infection, placental disorders, smoking, and poor diet, as well as history of iugr in a prior pregnancy. ...Read more
Yes! Via Epigenetics: Epigenetic changes are changes to the child's dna while still a fetus. Tehse changes are induced by the maternal diet. Increasingly epigenetic changes are being implicated in a host of common diseases occuring in offspring. These changes in the babies dna that do not involve changing the dna sequence but rather modify gene expression in children. ...Read more
Elevated Glucose: Diabetes is the leading cause of new blindnessin working-age adults (age 20-74) diabetic retinopathy (diabetes eye disease) does not have symptoms until the late stages. Diabetic retinopathy is treated with glucose control by the patient and primary care provider and lasers to retina by a physician (ophthalmologist). Newer techniques such as injections of special medications are available. ...Read moreSee 1 more doctor answer
Is effectively controlled htn, lipids, and glucose considered a risk factor for cad, absent of other risk factors (i.E. Genetic)?
Environment : Environmental factors can increase one’s chance of getting almost any type of psychological disorders if there is genetic or other physical predisposition. It is widely believed that for most psychological disorders emerge in this way (e.g., someone being exposed to undue stress--deployed to war zones returning with PTSD, schizophrenia due to genetic predisposition and stress ...Read more
Several: There several risk factors (CRF) for coronary artery disease, some modifiable and some not. Non-modifiable crfs include family history (genetics), sex and age. Some modifiable crfs which can be treated with medications or lifestyle changes include smoking, hypertension, diabetes and cholesterol status, particularly LDL or "bad" cholesterol. ...Read moreSee 1 more doctor answer
See below please: Cholestasis of pregnancy is a condition in which the normal flow of bile in the gallbladder is affected by the high amounts of pregnancy hormones. Cholestasis is more common in the last trimester of pregnancy. 1-2 pregnancies/1000 are affected by cholestasis. In severe cases, but not all, cholestasis may increase the risks for fetal distress, preterm birth, or stillbirth. Blood tests are key. ...Read more
Sure, but...: Liver disease comes in many varieties and manifestations: cholestasis (either intrahepatic or extrahepatic) with jaundice; infiltrative (like fatty liver, amyloidosis); fibrotic (trending toward cirrhosis); congestive (blood backs up into the liver); ischemic; shock injury; toxic (either metabolic or drug-related); hepatitis (infectious or otherwise, the liver cells are sick); familial; cancer... ...Read more
History/Physical/Lab: Cholestasis is diagnosed by doing a complete medical history, physical examination, and blood tests that evaluate liver function, bile acids, and bilirubin. Additionally, an ultrasound can de done to rule out gall bladder stones causing blockage. 1-2 preg/1000 is affected by cholestasis of pregnancy. It may be related to adverse pregnancy events like preterm labor, or at worse, stillbirth. ...Read more
In bad way: Upon diagnosis, most providers will prescribe ursodeoxycholic acid. While there is no cure for for it, and no way to guarantee a successful outcome, studies have shown a slightly better fetal and maternal outcome from administration of ursodeoxycholic acid, whereas Cholestyramine appears to only relieve itching. Giving vit k during delivary. Delivery by 37 completed weeks is considered crucial ...Read more
I have a kid and miscarried year ago.Want to get pregnant again. How should I prepare to avoid problems like cholestasis.?
History/Physical/Lab: Cholestasis is diagnosed by doing a complete medical history, physical examination, and blood tests that evaluate liver function, bile acids, and bilirubin. Additionally, an ultrasound can de done to rule out gall bladder stones causing blockage. 1-2 preg/1000 is affected by cholestasis of pregnancy. It may be related to adverse pregnancy events like preterm labor, or at worse, stillbirth. ...Read moreSee 1 more doctor answer
Itching & Jaundice: As well as elevated blood levels of bile acids. More common in scandinavia, south america, and multiple gestation pregnancy. An increased sensitivity of some women to the estrogen hormones of pregnancy lead to a reduced ability of their bodies to eliminate bile acids, causing them to accumulate. The condition usually resolves within 2-3 weeks of delivery. ...Read more
Cholestasis in pregnancy can be a serious problem. Usually occurs in the third trimester. It's caused by an excess accumulation of bile acids which can be toxic to the fetus. Leading to fetal distress and can even lead to fetal death. One of the most common symptoms is intense itching. Delivery at 36-37 weeks.
If not term, fetal monitoring and monitor liver enzymes and rx for itching. ...Read more
Pregnant 7 weeks, ALT level 76. I had cholestasis in previous pregnancy. How can i jelp myself now?
What meds are good for cholestasis of pregnancy?I had it once and don't want to experience it again.
UCDA: Ursodeoxycholic acid (udca) is used in the treatment of intrahepatic cholestasis of pregnancy (icp). We don't know exactly how udca works, but we think it improves bile salt loss from the liver into the bile, which reduces serum bile acid, liver enzyme, and bilirubin levels. This reduces itching, and the risk to the fetus/mother, allowing deliver closer to term. Udca is safe to use in pregnancy. ...Read moreSee 1 more doctor answer
How far along in pregnancy does cholestasis or pregnancy start? And what is cholestasis of pregnancy?
Cholestasis: Cholestasis of pregnancy is a condition in which the normal flow of bile in the gallbladder is affected by the high amounts of pregnancy hormones. Cholestasis is more common in the last trimester of pregnancy when hormones are at their peak, but it usually goes away within a few days after delivery. ...Read more
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