Top
40
Doctor insights on: Cholestasis Risk Factors

Share
Dr. Katharine Cox
79 doctors shared insights

Cholestasis (Definition)

When the flow of bile (chole) is held back (stasis). It can be from the liver cells not moving it (often from medications), or from the biliary tree being plugged by ...Read more


2

2
What are cardiovascular disease risk factors associated with obesity?

Obesity: Read this: http://www.Heart.Org/heartorg/gettinghealthy/weightmanagement/obesity/obesity-information_ucm_307908_article.Jsp.

Get a more detailed answer ›
3

3
Gestational diabetes mellitus--what are risk factors or causes?

Gestational diabetes mellitus--what are risk factors or causes?

Weight/Family Hist.: Obesity is a major risk for any diabetes. The other factor is genetics. There are many women of asian descent who have a normal weight (and body mass index), but develop gestational or regular diabetes. Obesity is one that people can modify though. ...Read more

See 1 more doctor answer
4

4
What are the risk factors for high risk pregnancies?

What are the risk factors for high risk pregnancies?

Threats to baby, mom: Risk factors include conditions that might affect the health of the fetus and/or pregnant woman. Those include higher chance for birth defects, >1 baby, prior preterm birth, diabetes, history of eclampsia. Many women at high risk for pregnancy complications have healthy babies, but they probably saw perinatologists, had extra testing or imaging, or underwent treatments or delivery with nicu aware. ...Read more

See 1 more doctor answer
5

5
What are cardiac risk factors

What are cardiac risk factors

Modifiable and non: Modifiable : smoking, lifetstyle, obesity, hypertension, hyperlipidemia, diabetes non-modifiable: heredity, age, gender, . ...Read more

See 3 more doctor answers
6

6
What are risk factors of cholelithiasis?

What are risk factors of cholelithiasis?

Variable: Many people may have gallstones and have no symptoms at all. Some people will get upper abdominal pressure, bloating, discomfort, nausea or vomiting. Eating fatty foods may make more discomfort. Vomiting, inability to eat are common. Serious infections sometimes can occur, and sometimes the gallstone can cause bile duct blockage with marked pain, vomiting, jaundice, and sometimes pancreatitis. ...Read more

7

7
What risk factors are associated with coronary heart disease?

What risk factors are associated with coronary heart disease?

Atherosclerosis: Depends on one's personal risks smoking, obesity, hypertension, hyperlipemia, diabetes , family history. Simply, one blocks the feeding artery to part of the heart muscle and low flow, or no flow causes ischemia which cause death of the heart cells, which is a heart attack! myocardial infarction is the medical term.Ekg and lab tests show the damage. ...Read more

8

8
What are the risk factors associated with gestational diabetes?

What are the risk factors associated with gestational diabetes?

Many: Diabetes can affect the developing baby throughout the pregnancy. In early pregnancy, a mother's diabetes can result in birth defects and an increased rate of miscarriage. Many of the birth defects that occur affect major organs such as the brain and heart. During the 2nd & 3rd trimester, a mother's diabetes can lead to over-nutrition & excess growth of the baby. ...Read more

See 2 more doctor answers
9

9
Describe risk factors of coronary heart disease?

Describe risk factors of coronary heart disease?

See below: The most common riak factors are : family history . Hypertension, diabetes, high cholesterol, smoking ., age>45 in men, >55 in women. ...Read more

10

10
Possible risk factor, and etiology of iugr?

Possible risk factor, and etiology of iugr?

Multifactorial: There are a number of medical conditions preexisting in the mother that can increase risk of iugr, including hypertension, lupus, kidney disease, and sickle cell; fetal conditions such as abnormal chromosomes; twins or more; infection, placental disorders, smoking, and poor diet, as well as history of iugr in a prior pregnancy. ...Read more

11

11
Can maternal diet during pregnancy influence offspring obesity risk?

Can maternal diet during pregnancy influence offspring obesity risk?

Yes! Via Epigenetics: Epigenetic changes are changes to the child's dna while still a fetus. Tehse changes are induced by the maternal diet. Increasingly epigenetic changes are being implicated in a host of common diseases occuring in offspring. These changes in the babies dna that do not involve changing the dna sequence but rather modify gene expression in children. ...Read more

12

12
What factors increase the risk of developing diabetes?

What factors increase the risk of developing diabetes?

Obesity. Genes.: Fat tissue in the body increases resistance to insulin, which ultimately causes diabetes. As well, 90% of family members of diabetics will be hard wired genetically to get diabetes. ...Read more

13

13
What risk factors are associated with diabetic retinopathy?

What risk factors are associated with diabetic retinopathy?

Elevated Glucose: Diabetes is the leading cause of new blindnessin working-age adults (age 20-74) diabetic retinopathy (diabetes eye disease) does not have symptoms until the late stages. Diabetic retinopathy is treated with glucose control by the patient and primary care provider and lasers to retina by a physician (ophthalmologist). Newer techniques such as injections of special medications are available. ...Read more

See 1 more doctor answer
15

15
Could environmental factors increased chance of schizophrenia?

Could environmental factors increased chance of schizophrenia?

Environment : Environmental factors can increase one’s chance of getting almost any type of psychological disorders if there is genetic or other physical predisposition. It is widely believed that for most psychological disorders emerge in this way (e.g., someone being exposed to undue stress--deployed to war zones returning with PTSD, schizophrenia due to genetic predisposition and stress ...Read more

16

16
What factors increases the risk of esophageal cancer?

What factors increases the risk of esophageal cancer?

Chronic Heartburn: Severe gastro-esophageal reflux can lead to adenocarcinoma of the esophagus. If you have severe heartburn, see your doctor so you can be screened for pre-cancerous changes of your esophagus. ...Read more

See 3 more doctor answers
19

19
What are risk factors for coronary heart disease?

What are risk factors for coronary heart disease?

See below: The most common riak factors are : family history . Hypertension, diabetes, high cholesterol, smoking ., age>45 in men, >55 in women. ...Read more

20

20
What are risk factors for coronary artery disease?

What are risk factors for coronary artery disease?

Several: There several risk factors (CRF) for coronary artery disease, some modifiable and some not. Non-modifiable crfs include family history (genetics), sex and age. Some modifiable crfs which can be treated with medications or lifestyle changes include smoking, hypertension, diabetes and cholesterol status, particularly LDL or "bad" cholesterol. ...Read more

See 1 more doctor answer
21

21
What does cholestasis mean?

What does cholestasis mean?

Bile flow: Usually means disruption (slowing or blockage) of bile flow from the liver. ...Read more

22

22
What exactly is cholestasis?

What exactly is cholestasis?

Bile flow: Usually means disruption (slowing or blockage) of bile flow from the liver. ...Read more

23

23
What is the definition or description of: cholestasis?

What is the definition or description of: cholestasis?

Bile plugged: This means the flow of bile (chole) is held back (stasis). It can be from the liver cells not moving it (often from medications), or from the biliary tree being plugged by stone, tumor, scar, or perhaps something else. ...Read more

24

24
What is cholestasis of pregnancy?

What is cholestasis of pregnancy?

See below please: Cholestasis of pregnancy is a condition in which the normal flow of bile in the gallbladder is affected by the high amounts of pregnancy hormones. Cholestasis is more common in the last trimester of pregnancy. 1-2 pregnancies/1000 are affected by cholestasis. In severe cases, but not all, cholestasis may increase the risks for fetal distress, preterm birth, or stillbirth. Blood tests are key. ...Read more

25

25
Can liver disease cause cholestasis?

Can liver disease cause cholestasis?

Sure, but...: Liver disease comes in many varieties and manifestations: cholestasis (either intrahepatic or extrahepatic) with jaundice; infiltrative (like fatty liver, amyloidosis); fibrotic (trending toward cirrhosis); congestive (blood backs up into the liver); ischemic; shock injury; toxic (either metabolic or drug-related); hepatitis (infectious or otherwise, the liver cells are sick); familial; cancer... ...Read more

26

26
Does cholestasis cause an itchy rectum?

Does cholestasis cause an itchy rectum?

No: Cholestasis should have no particular effect on the rectum itself. ...Read more

27

27
Is cholestasis determined by a basic liver function panel?

Is cholestasis determined by a basic liver function panel?

History/Physical/Lab: Cholestasis is diagnosed by doing a complete medical history, physical examination, and blood tests that evaluate liver function, bile acids, and bilirubin. Additionally, an ultrasound can de done to rule out gall bladder stones causing blockage. 1-2 preg/1000 is affected by cholestasis of pregnancy. It may be related to adverse pregnancy events like preterm labor, or at worse, stillbirth. ...Read more

28

28
My 10 year old son has cholestasis liver. What should be done?

My 10 year old son has cholestasis liver. What should be done?

GI Consult: He should see a pediatric gastroenterologist for a full evaluation of the cause of the cholestasis and for treatment. ...Read more

29

29
Can cholestasis reoccur outside once you have had Cholestasis in Pregnancy?

Can cholestasis reoccur outside once you have had Cholestasis in Pregnancy?

Cholestasis: If someone developed cholestasis in pregnancy then they are at risk to get it again in future pregnancies. If they are having issues while not pregnant then a complete liver and and gallbladder evaluation should be done to look for underlying hepatic and biliary disease ...Read more

30

30
My wife has been diagnosed with cholestasis. How does this affect pregnancy?

My wife has been diagnosed with cholestasis. How does this affect pregnancy?

In bad way: Upon diagnosis, most providers will prescribe ursodeoxycholic acid. While there is no cure for for it, and no way to guarantee a successful outcome, studies have shown a slightly better fetal and maternal outcome from administration of ursodeoxycholic acid, whereas Cholestyramine appears to only relieve itching. Giving vit k during delivary. Delivery by 37 completed weeks is considered crucial ...Read more

32

32
How is cholestasis of pregnancy diagnosed?

History/Physical/Lab: Cholestasis is diagnosed by doing a complete medical history, physical examination, and blood tests that evaluate liver function, bile acids, and bilirubin. Additionally, an ultrasound can de done to rule out gall bladder stones causing blockage. 1-2 preg/1000 is affected by cholestasis of pregnancy. It may be related to adverse pregnancy events like preterm labor, or at worse, stillbirth. ...Read more

See 1 more doctor answer
34

34
What causes cholestasis of pregnancy and what are the symptoms?

Itching & Jaundice: As well as elevated blood levels of bile acids. More common in scandinavia, south america, and multiple gestation pregnancy. An increased sensitivity of some women to the estrogen hormones of pregnancy lead to a reduced ability of their bodies to eliminate bile acids, causing them to accumulate. The condition usually resolves within 2-3 weeks of delivery. ...Read more

35

35
In pregnancy, can u have cholestasis without the itching?

In pregnancy, can u have cholestasis without the itching?

Yes: Bloodwork will show cholestatic changes. Pruritis (itching) is common but not always present. ...Read more

See 1 more doctor answer
36

36
Can chronic sleep loss cause cholestasis? Can it cause liver problems?

Can chronic sleep loss cause cholestasis?  Can it cause liver problems?

Not really.: Sleep loss is not known to cause liver disease or cholestasis. On the contrary, however, severe cholestasis can result in sleep loss, if the itching from the cholestasis makes it difficult to sleep. ...Read more

38

38
What meds are good for cholestasis of pregnancy?I had it once and don't want to experience it again.

UCDA: Ursodeoxycholic acid (udca) is used in the treatment of intrahepatic cholestasis of pregnancy (icp). We don't know exactly how udca works, but we think it improves bile salt loss from the liver into the bile, which reduces serum bile acid, liver enzyme, and bilirubin levels. This reduces itching, and the risk to the fetus/mother, allowing deliver closer to term. Udca is safe to use in pregnancy. ...Read more

See 1 more doctor answer
39

39
How far along in pregnancy does cholestasis or pregnancy start? And what is cholestasis of pregnancy?

Cholestasis: Cholestasis of pregnancy is a condition in which the normal flow of bile in the gallbladder is affected by the high amounts of pregnancy hormones. Cholestasis is more common in the last trimester of pregnancy when hormones are at their peak, but it usually goes away within a few days after delivery. ...Read more