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Doctor insights on: Chlorpheniramine Maleate Overdose

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Will 32-48 mg of chlorpheniramine maleate make me sick or should it have no affect?

Will 32-48 mg of chlorpheniramine maleate make me sick or should it have no affect?

That's an overdose: 32-48 mg is definitely an overdose of chlorpheniramine. The maximum over-the-counter recommended dose is 4 mg every 4-6 hours (24 mg max/day). There are extended-release forms that have higher doses, but they are also meant to last 12 hours or longer. 32-48 mg will likely cause dry mouth, eyes, etc., as well as excessive drowsiness. I don't recommend at all that high a dose.

Overdose (Definition)

When the maximum dose of medication ...Read more


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I can't find any information on the medication chlorpheniramine maleate 4mg on here, any information?

I can't find any information on the medication chlorpheniramine maleate 4mg on here, any information?

Antihistamine: Chlorpheniramine is a first generation antihistamine. It has been around for a long time and is available in a lot of over the counter medications. While effective for mild allergies it can cause drowsiness in many people. Second generation antihistamines such as Claritin (loratadine) or Allegra (fexofenadine) are often a better choice as they are non-sedating.

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Does chlorpheniramine maleate 4 mg make you drowsy?

Does chlorpheniramine maleate 4 mg make you drowsy?

It can: Chlorpheniramine is a first generation antihistamine and compared to other first generation antihistamines (like benadryl) it is typically less drowsy. However, it is more likely to cause drowsiness compared to claritin, (loratadine) allegra, etc.

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Are pheniramine maleate and chlorpheniramine maleate the same?

Antihistamines: Both pheniramine and chlorpheniramine are 1st-generation antihistamines and both tend to be more sedating than drugs such as allegra, Claritin (loratadine) and zyrtec.

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What are the differences between chlorpheniramine maleate and pheniramine maleate?

What are the differences between chlorpheniramine maleate and pheniramine maleate?

Very similar: Both are older antihistamines and very close in their chemical structure. The chlorpheniramine has a chlorine in it, while the pheniramine doesn't. Pheniramine is: dimethyl[3-phenyl-3- (pyridin-2-yl)propyl]amine while chlorpheniramine is 3- (4-chlorophenyl)-n, n-dimethyl- 3-pyridin-2-yl-propan-1-amine.

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Dexchloropheniramine maleate tablets have 2mg; chlorpheniramine maleate tablets had 4mg. Dex isomer's more potent? Or ploy to sell more tablets?

Tab difference: Hello ~ dex~etc is a totally different substance to chlorphen~etc base. Each compound in organic chem has completely different properties, by adding free radicals (-H, -OH, -S03, -S04, -NH3, NH4) This is not a scam but dose equivalents. Do not mess with dose advised on label! Take AS DIRECTED! ALWAYS!

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Chlorpheniramine maleate or allegra (fexofenadine) which is safer?

Chlorpheniramine maleate or allegra (fexofenadine) which is safer?

Both: Antihistamines are extremely safe. Any antihistamine can cause drowsiness, but second-generation antihistamines are much less likely to do so. Drowsiness with chlorpheniramine is the biggest side effect to watch for, between these two meds.

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What are the differences between chlorpheniramine maleate and dexchlorpheniramine maleate?

What are the differences between chlorpheniramine maleate and dexchlorpheniramine maleate?

Closely related: Both medications are potent antihistamines. Both have similar side effects, mainly sedation and anti-cholinergic (dry mouth, larger pupils, may cause constipation and in older men, difficulty in urination. Dexchlorpheniramine requires a prescription. Its chemical structure is only minimally different from chlorpheniramine.

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I regularly take a four-hour antihistamine, chlorpheniramine maleate, because it seems to help with digestion. Are there any issues with extended use?

I regularly take a four-hour antihistamine, chlorpheniramine maleate, because it seems to help with digestion. Are there any issues with extended use?

Yes: First is tolerance, meaning that you would have to increase the dose to get the same effect. Second, side effects are more prone to appear with extended use, and some are serious, hence the need of medical supervision. Third, it isn't meant to help digestion, if you have a problem with digestion / indigestion and not resolved, you need to see your doctor. Good luck

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Can taking the OTC chlorpheniramine maleate (antihistamine) make you sweaty?

Can taking the OTC chlorpheniramine maleate (antihistamine) make you sweaty?

Possible, unlikely: It can cause you to be sweaty, but this would be unlikely.

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Can I take chlorpheniramine maleate and cetirizine dihydrochloride (Piriton) at the same time?

Yes: They are both antihistamines but the chlorpheniramine is a broad spectrum sedating one and cetirizine is a narrow non-sedating one. They are meant to do the same thing but depends on why you are taking it.

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Can you take aspirin with the anti-histamine chlorpheniramine maleate?

Can you take aspirin with the anti-histamine chlorpheniramine maleate?

Yes: These two drugs have no cross over and will neither enhance or interfere with each others activity. They are both over the counter, inexpensive and surprisingly effective.

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Is chlorpheniramine maleate safe to use as a everyday sleeping aid or at least for occasional sleeplessness?

Is chlorpheniramine maleate safe to use as a everyday sleeping aid or at least for occasional sleeplessness?

Try to avoid long: Term use. Retire & rise same time each day. Keep bedroom dark & cool & use only for sex & sleep. Turn off tv. No naps. Exercise regularly but not in late evening. No caffeine for 6 hrs & no alcohol or tobacco w/i 2 hrs of sleep. Keep dinner moderate sized & finish at least 2 to 3 hrs before sleep. Can try warm milk, Chamomile tea or melatonin along w light reading, warm bath or lavender scent.

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I'm 34 weeks pregnant I would like to know if I could take chlorpheniramine maleate for my sever allergies?

I'm 34 weeks pregnant I would like to know if I could take chlorpheniramine maleate for my sever allergies?

Yes: Chlorpheniramine or Chlor-Trimeton is a 1st generation antihistamine that is listed as a pregnancy category B medication. There is no evidence of 2nd or 3rd trimester risk. Given the above information this medication is likely fine to take while 34 weeks pregnant.

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Daughter is 12 weeks old. Have got cold and cough. Doctor has given phenylephrine hydrochloride chlorpheniramine maleate drops. Is this preferable?

Daughter is 12 weeks old. Have got cold and cough. Doctor has given phenylephrine hydrochloride chlorpheniramine maleate drops. Is this preferable?

No: These medications in a 12 week old can cause more problems than they solve. Studies clearly show no benefit of these medications for infants with colds, and the medications can cause problems with heart rate, poor feeding, irritability among other symptoms. Use a humidifier, nasal saline with bulb syringe to clear secretions and do small but frequent feedings. Monitor wet diapers and temperature.

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Could chlorphenamine maleate 12 mg work for a headache?

Could chlorphenamine maleate 12 mg work for a headache?

Headache: It might help depending on what type of headache you have. If you have an allergic headache, the chlorophenamine might help.

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Hi, is it safe to take chlorphenamine maleate 3 hours after cetrizine? Or should I get them to hospital as he made mistake with timings?

Safe: And depends on the dosing, hopefully both were within the recommended dosage, side effects might be pronounced a bit. If doing fine, no problem, and skip the next dose if you can do without, but if you have excessive drowsiness or other strange symptom, go to the hospital, good luck