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Doctor insights on: Chloroquine Hydrochloride

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Dr. Eric Weisman
5 Doctors shared insights

Chloroquine Hydrochloride (Overview)

Chloroquine hydrochloride is an anti-malaria agent which is a kind of antibiotic and antimicrobial.


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What will happen if a human eats chloroquine?

What will happen if a human eats chloroquine?

Depends on the dose: Chloroquine is an anti-malarial medication, it is meant to be taken by prescription only. It does have some side effects, but at standard, recommended doses it is usually well tolerated. ...Read more

Dr. Eric Weisman
5 Doctors shared insights

Chloroquine Hydrochloride (Overview)

Chloroquine hydrochloride is an anti-malaria agent which is a kind of antibiotic and antimicrobial.


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How does the antimalarial chloroquine work? Does it passively diffuse into red blood cells to thwart the malaria parasite or does it enter the red blood cells by an active transport process?

How does the antimalarial chloroquine work? Does it passively diffuse into red blood cells to thwart the malaria parasite or does it enter the red blood cells by an active transport process?

Chloroquine: Chloroquine concentrates up to several 1000-fold in the food vacuole of the parasite. Possible mechanisms for this selective accumulation of Chloroquine in the food vacuole are: 1) protonation and ion trapping of the Chloroquine due to the low ph of the food vacuole; 2) active uptake of Chloroquine by a parasite transporter (s); and/or 3) binding of Chloroquine to a specific receptor in the food va. ...Read more

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Is chloroquine is safe in pregnency in hot climate like. India?

Is chloroquine is safe in pregnency in hot climate like. India?

Clarification: There are many areas in india where there are mixed forms of malaria and Chloroquine therefore is not reccomended. P vivax malaria does occur in india but so does resistant p falciparum. An alternative is to take pregnancy safe Mefloquine instead since the usual combo of Chloroquine plus proguanil cannot be used. Again Chloroquine alone is not for india. ...Read more

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Is metformin hydrochloride (glucophage xr) nephro toxic?

Is metformin hydrochloride (glucophage xr) nephro toxic?

Not exactly: If you have a moderate degree of renal disease, metformin can cause lactic acidosis, which is very serious. If you do not have renal disease, metformin is quite safe. ...Read more

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How can we cure nervousness and mild termor caused by taking ciprofloxin hydrochloride? Is this side effect reversible after being controled?

How can we cure nervousness and mild termor caused by taking ciprofloxin hydrochloride? Is this side effect reversible after being controled?

Cipro (ciprofloxacin) tremor: These side effects resolve after you come off cipro (ciprofloxacin). It can take 10 to 60 days. To help, exercise steadily twice a day, minimize caffeine and sugar, and as able get involved in relaxation maneuvers and even yoga. If protracted, acupuncture helps tremendously. Be careful with exercise. Stay light and steady. Do not overload muscles. Walking briskly, very easy jog, cycling, rowing best. ...Read more

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What are the common side effects of plaquenil (hydroxychloroquine) prescription hydro chlorquine?

What are the common side effects of plaquenil (hydroxychloroquine) prescription hydro chlorquine?

Most do fine: Most patients do very well on hydroxychloroquine. Common side effects include allergy to the medication, GI disturbances such as nausea or diarrhea, and changes of pigmentation in the skin or hair (this is not a complete list). You should also be tested for an enzyme called g6pd before starting, and you should have at least one eye exam annually while on the drug. ...Read more

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Is there a relationship between vision problems (visual field loss, macular hole) and long term use of antimalarials (23 yr)? Chloroquine, oroguanil..

Is there a relationship between vision problems (visual field loss, macular hole) and long term use of antimalarials (23 yr)? Chloroquine, oroguanil..

Yes, yes, yes: Short term use for malarial prophylaxis rarely has serious side effects, usually minor GI side effects. Long term definitely has potentially very serious side effects, involving many sensory organs. First is visual, and can be multiple things including retinal damage, sight damage, corneal defects. A certified ophthalmologist must check fully the eyes before, and during long term use. ...Read more

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Could chloroquine interact with lidocaine?

Could chloroquine interact with lidocaine?

I was unable to: Find interactions between Chloroquine ; Lidocaine using a drug interaction checker. But that is never a complete guarantee. ...Read more

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Is chloroquine is safe in pregnency in hot climate like. India?

Clarification: There are many areas in india where there are mixed forms of malaria and Chloroquine therefore is not reccomended. P vivax malaria does occur in india but so does resistant p falciparum. An alternative is to take pregnancy safe Mefloquine instead since the usual combo of Chloroquine plus proguanil cannot be used. Again Chloroquine alone is not for india. ...Read more

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What will happen if a human eats chloroquine?

Depends on the dose: Chloroquine is an anti-malarial medication, it is meant to be taken by prescription only. It does have some side effects, but at standard, recommended doses it is usually well tolerated. ...Read more

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Could chloroquine interact with lidocaine?

I was unable to: Find interactions between Chloroquine ; Lidocaine using a drug interaction checker. But that is never a complete guarantee. ...Read more

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I wanted to know is chloroquine used in treatment of lepra reaction?

Chloroquine: I see articles referring to research on the use of chloroquine for treatment of Lepra reaction. ...Read more

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Can you tell me how chloroquine kill the malaria parasite?

Can you tell me how chloroquine kill the malaria parasite?

Antimalarial drugs: It's a little bit technical - but basically the medicine acts as a 'poison' for the malaria parasite. Plasmodium species have to digest hemoglobin (inside the red blood cell) to survive - but the heme molecule can be toxic when released. Therefore, the parasite tries to sequester that away. Chloroquine interferes with that step - thus leading to a slow poisoning of the parasite. Hope that helps. ...Read more

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What is the difference between proguanil, chloroquine, quinine and mefloquine?

Here you go>>: See: http://www. Cdc. Gov/malaria/travelers/drugs. Html. This is too much to adequately cover in 400 characters or less. ...Read more

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Prescription written for 250mg Chloroquine, med given from pharmacy, ChlorproPAMIDE 250mg. Are these the same?

Prescription written for 250mg Chloroquine, med given from pharmacy, ChlorproPAMIDE 250mg. Are these the same?

Not even close: Hi. Nope, chloroquine and chlorpropamide are not in the same category of drugs, and are for completely different indications. Either the doc or the pharmacist screwed up BIG TIME. Are you diabetic or are you trying to prevent malaria...aw heck, what's the difference??? Good luck! ...Read more

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How can chloroquine cause damage to the eye?

How can chloroquine cause damage to the eye?

Maculopathy: Chloroquine can cause damage to the central part of the retina, the macula, of the eye. Chloroquine is rarely used in the U.S. But is used worldwide as a treatment for malaria. ...Read more

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I have psoriasis and arthritis for 25 years and have been taking hydroxy chloroquine sulfate 200mg sulfasalazine 500mg how can I get you to fill rx?

I have psoriasis and arthritis for 25 years and have been taking hydroxy chloroquine sulfate 200mg sulfasalazine 500mg how can I get you to fill rx?

See your doctor: If you have been getting this medicine for 25 years, you must have one. Your condition does require periodic evaluation and ongoing monitoring. ...Read more

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I am an african and aa blood type. I have just treated malaria with my usual lonart ds drug three days ago and suprisingly the aches and pain symptoms still persist. My body also itch in a manner akin to the days of chloroquine drugs. What could be wrong?

I am an african and aa blood type. I have just treated malaria with my usual lonart ds drug three days ago and suprisingly the aches and pain symptoms still persist. My body also itch in a manner akin to the days of chloroquine drugs. What could be wrong?

Several possibities: You may be reacting to side-effects of the medication, the parasite may be resistant to the medication you are receiving, you may have an illness either along with or in place of the diagnosis of malaria. See your doctor. ...Read more

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I've been having diarrhea, and nausea for a week, it's not the first time this happened. What can be the cause. Am taking chloroquine, prednisone.

I've been having diarrhea, and nausea for a week, it's not the first time this happened. What can be the cause. Am taking chloroquine, prednisone.

Many causes: Depending on how long this has been going on, there could be many explanations. Stress, depressed mood, anxiety, medications, viruses, pregnancy. I'd see your doctor for more answers. ...Read more

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Would it be possible to ask doctor to prescribe Chloroquine/Amodiaquine for off-label use? Harvard recently found them extremely effective for PD.

Would it be possible to ask doctor to prescribe Chloroquine/Amodiaquine for off-label use? Harvard recently found them extremely effective for PD.

You can always ask: A healthy patient-physician relationship should make you comfortable making reasonable request. Having said that, if I know which study you are referring to - one has to keep in mind the study is very much a laboratory study showing chloroquine/amodiaquine can activate Nurr1, a "master switch" for brain regeneration, in petri dish. Clinical efficacy has NOT being proven. ...Read more

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How does the antimalarial chloroquine work? Does it passively diffuse into red blood cells to thwart the malaria parasite or does it enter the red blood cells by an active transport process?

Chloroquine: Chloroquine concentrates up to several 1000-fold in the food vacuole of the parasite. Possible mechanisms for this selective accumulation of Chloroquine in the food vacuole are: 1) protonation and ion trapping of the Chloroquine due to the low ph of the food vacuole; 2) active uptake of Chloroquine by a parasite transporter (s); and/or 3) binding of Chloroquine to a specific receptor in the food va. ...Read more

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Is there a relationship between vision problems (visual field loss, macular hole) and long term use of antimalarials (23 yr)? Chloroquine, oroguanil..

Yes, yes, yes: Short term use for malarial prophylaxis rarely has serious side effects, usually minor GI side effects. Long term definitely has potentially very serious side effects, involving many sensory organs. First is visual, and can be multiple things including retinal damage, sight damage, corneal defects. A certified ophthalmologist must check fully the eyes before, and during long term use. ...Read more

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