Doctor insights on:
Chlor Trimeton Sedating Antihistamine
Possible, unlikely: It can cause you to be sweaty, but this would be unlikely. ...Read more
I regularly take a four-hour antihistamine, chlorpheniramine maleate, because it seems to help with digestion. Are there any issues with extended use?
Yes: First is tolerance, meaning that you would have to increase the dose to get the same effect. Second, side effects are more prone to appear with extended use, and some are serious, hence the need of medical supervision. Third, it isn't meant to help digestion, if you have a problem with digestion / indigestion and not resolved , you need to see your doctor. Good luck ...Read more
Benadryl (diphenhydramine).....: is probably the most readily available sedating antihistamine. It is a common ingredient in over-the-counter (OTC) preparations for sleep, such as Tylenol (acetaminophen) PM -- the PM part is diphenhydramine, the generic name for Benadryl. Another one I like to use is hydroxyzine (also known as Vistaril or Atarax) but that is only available as a prescription, however its metabolite is Zyrtec, which is OTC. ...Read more
I understand that one cannot become addicted to antihistamines, however, can't people become addicted to the sedating effects of drugs?
Tolerance: You become tolerant to the sedative effect of first generation antihistamines and with time you will no longer feel sedated from them. If you are using then as a sleep aid, will you need more with time to achieve the same level of sedation. It is not an addiction, it is tolerance to the medication. ...Read more
I have anaphylaxis from Benadryl (diphenhydramine) (documented by ED mds), is chlor trimeton ok to take instead?
No guarantee: Chlortimeton is a different chemical compared to benadryl (diphenhydramine) (Alkylamine vs Ethanolamine derivatives) so in theory it should be ok.Actual anaphylaxis reaction to antihistamines is not only rare, but every case report, there have been other drugs involved (co-ingested). Consider specific allergy testing because anaphylaxis is life-threatening and if it wasn't the benadryl (diphenhydramine) you need to know absolutely. ...Read moreSee 1 more doctor answer
Much longer: Benadryl (diphenhydramine) leaves the system about twice as fast. It's half-life (time for 1/2 of it to leave the body) is 3.4 to 9.2 hours. Chlor-trimeton (chlorpheniramine)'s half-life is 20-24 hrs for adults and 10-13 hrs in children. That means Benadryl is 75% gone in 7-18h rs and chlor-trimeton's still going strong after 40-48 hrs (in adults). ...Read more
What is the dosage of Benadryl (diphenhydramine) for a 23 mo. Old? He is taking chlorpheniramine maleate every 6 hrs. But hasn't taken it since yesterday.Also coughing
Benadryl (diphenhydramine): Do not use it for a 23 month old. Ask your pediatrician for something else. ...Read more
If I have developed resistance to benadryl's sedating effects( +/-150mg), will it still work4allergy?
Give it a try: Diphenhydramine (benedryl) is a very effective antihistamine, holding on to histamine binding sites better than some products. Its drawback other than sedation has been its limited duration of effect, eclipsed by products like zyrtec (cetirizine) that can last all day. Sedation is not a measure of its worth, only its ability to get into your brain and mess with neurotransmitters. ...Read moreSee 1 more doctor answer