Doctor insights on:
Childhood Leukemia In Children
A malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more
Wish we knew: Leukemia, like most malignancies, is due to abnormal changes in the genetics of a cell line in the body, which cause it to proliferate in a manner which overwhelms the normal cells of the body. The change is generally random, an accident statistically of cellular division and not due to some failure of parenting. Whoever discovers the real cause will be an international hero. ...Read more
Many other tests:
For diagnosis, I agree with a CBC and a bone marrow evaluation. The best test for diagnosis is done by flow cytometry and can detect even 1 leukemia cell among 10, 000 normal cells: a powerful test.
To adequately treat childhood leukemia, there are many tests that help characterize the leukemia into a low, medium or high risk group. These tests are genetic-based tests of the leukemia cells. ...Read more
Multiple: Kids with leukemia can have different presentations. Fever, anemia (low red blood cells--causes paleness and tiredness), easy bruising (not just from the knee to ankle), easy bleeding, bone or joint pain, limp, poor appetite, irritability, headache, seizures, swollen lymph nodes (glands), or shortness of breath. Many of these can have multiple causes, so if you're worried, see a pediatrician! ...Read more
Pretty old for kids: The most common leukemias that occur in kids also occur in adults. It is possible to have leukemia as an young adult and be treated according to pediatric protocols, which generally are more intensive. The protocols for childhood leukemia allow for treatment of "kids" up to 30 years of age. ...Read more
Four major types...: Acute lymphoblastic leukemia (all), acute myelogenous leukemia (aml), chronic myelogenous leukemia (cml), and juvenile myelomonocytic leukemia (jmml). Each of these can be further subdivided. ...Read more
See below: There are no environmental influences.Get a more detailed answer ›
I just read that drinking coffee while pregnant can increase childhood leukemia. I drank it with both pregnancies! Dr said it was okay. What's the deal?
That's baloney: I'm sorry someone troubled you with something so foolish. Retrospective epidemiologic studies generate a huge amount of junk associations. Anyone who's scientifically literate can recognize the bogus ones. If I were to do a study to find out whether eating licorice causes your kids to be born with a unibrow, I'd get a positive result. Please don't worry about this. ...Read more
Can sleeping with electric blanket on throughout the night cause childhood leukemia, breast cancer, or other cancers?
No: Interesting question, but no evidence that heat influences the origin of these disorders. ...Read more
Unknown: Most leukemias in adults and children do not have a specific etiology. Some leukemias in children can be linked to genetic abnormalities like down's syndrome, neurofibromatosis, bloom syndrome, and others. Ethnicity may play a role in all, hispanic children tend to have higer risk. High birth weight has been associated with higher risk though really this is unclear. Other factors are inconsistent. ...Read more
See below: It is a blood cancer in children. With advances in the treatment the prognosis has improved quite a bit. It used to be universally fatal disease about 15 years ago but now most children survive and get cured. ...Read more
Between 2003-2007, 1257 children (age 0-19 years old) were diagnosed with acute lymphoblastic leukemia in canada. See the following website for more information about statistics in canada:
http://www.Cancer.Ca/en/cancer-information/cancer-type/leukemia-childhood/statistics/? Region=on. ...Read more
Usually they thrive: The cure rate for all childhood leukemias has improved tremendously over the past few decades, and much effort now is directed toward minimizing long term side effects, such as numbness, secondary cancers, or slowed mentation. A very reasonable goal today is for the child to be cured and lead a perfectly normal life. ...Read more
Yes: It depends upon the type of therapy a person received. For men who have completed thereapy, analysis of semen by a urologist interested in reproductive issues may help with guidance. Some men who have already reached puberty before therapy may choose to bank their sperm to give an added chance at fathering children. ...Read more
Yes: Ask your oncologist about fertility sparing regimens if you want to have children. There are a variety of ways to spare child bearing ability if you have leukemia from freezing sperm to harvesting eggs to using chemotherapy and radiation that reduces side effects on reproductive organs. Lots depends on your type of leukemia, age, etc. So it important to ask your oncologist for your specifics.... ...Read more