Doctor insights on:
Chemotherapy Liver Damage
After 4 cycles of chemotherapy should a liver met start reducing in size ? Is 16 mm classed large ?
Kinetics of response: Faster growing tumors tend to respond quicker, but tumors can be resistant. Typically 4 cycles of chemotherapy is enough time to know whether the disease is responding. Whether to continue treatment depends on the goals of care. Stable disease is better than progression, so more treatment may be fine if side effects are manageable. 16 mm is not large yet still represents millions of tumor cells. ...Read moreSee 1 more doctor answer
This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more
How effective is chemotherapy irinotecan for a liver met and node.? Does it only work in some patients ?
Good drug: Irinotecan hydrochloride or Camptosar, (irinotecan) CPT-11 is a chemotherapy drug made from a plant alkaloid known as a topoisomerase I inhibitor. It works by blocking an enzyme in cells called topoisomerase I. needed to keep DNA in shape when dividing. The drug useful in metastatic colon cancer to liver where it can convert the mets to resectable. ...Read more
Find a good team: Colorectal cancer with spread to the liver is a hotly debated and controversial topic. Multiple variables include - the location of the tumor, the symptoms it is producing, the location of the liver mets and their potentail for surgical removal. You need an experienced team that deals with this commonly (surgical and medical oncologists, maybe rad onc, as well). Good ct/pet is vital. ...Read moreSee 2 more doctor answers
My father operated for ca rectum now he had multiple mets in liver what's is prognosis of chemotherapy in this case and what is life expectancy???
Hard to say: I am sorry for your father's illness. We can not say how long anyone might live, and response to chemotherapy can vary among different people. Your father's oncologist can best explain the expected response to treatment. Spending time with your father will help both of you through this time. ...Read more
What If no forms of chemotherapy work on a colon cancer pt who has a liver met ? Are there other options ?
Radiation and surgery: Aside from chemotherapy, the 2 types of treatment for cancer are radiotherapy & surgery. Liver mets, if they block a duct or cause a "local" problem can be treated with radiation beam to alleviate suffering. If the patient is strong enough to withstand it, surgery and/or brachytherapy (radiation implants) can be tried; however, colon cancer is a systemic problem and chemo is the main modality. GL. ...Read moreSee 2 more doctor answers
Do these CEA readings mean chemotherapy not working in a colon cancer pt
August 9.8, October 8, dec 9, jan 10. Met to the liver ?
Since on chemotherapy , each month in a row CEA rising as:
Colon cancer pt with a liver meta.is this progression ?
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