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Chemotherapy Hormone Receptor Positive Node Breast Cancer
D/W oncologist: Treatment will depend not only the stage but also the biology of the cancer- whether it is estrogen positive, her2neu positive, whether it is lymph node positive or not. Also depends on your preference and overall health condition. Different test like oncotype dx, mammaprint can give you more info-re- recurrence risk of cancer and will be helpful in choosing the right therapy for you.D/w your md. ...Read moreSee 2 more doctor answers
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Is there a benefit to chemotherapy in hormone receptor positive, node positive postmenopausal breast cancer?
Often: There is increasing data based on the oncotype DX test in women with 1-3 positive notes that shows that some women will not get much benefit from chemo and some will get a great deal. It can be useful in cases where a woman is reluctant to take chemo. This is done on tissue that has been already removed. Most oncologists believe that women who have multiple positive nodes should get chemotherapy. ...Read moreSee 1 more doctor answer
Up to 1 year's worth: Herceptin (trastuzumab) can be given together with initial chemotherapy for the first 4-6 months then subsequently by itself for a total of 1 year. If chemotherapy was given first without Herceptin (trastuzumab) then Herceptin (trastuzumab) can be given for a full year by itself. The usual cycle runs every 3 weeks (17-18 cycles in one full year). ...Read moreSee 1 more doctor answer
It depends.: Tamoxifen is used to treat hormone-sensitive breast cancer. This is determined by checking for estrogen receptors (er) and Progesterone receptors (pr) on the cancer. If the cancer is er+ and pr- (or vice-versa), it should respond to tamoxifen. However, if the cancer is er- and pr-, tamoxifen is not effective. ...Read moreSee 2 more doctor answers
Survival rate for triple neg receptors for early stage breast cancer after chemo treatment? No lymph nodes involve, stage 1b, grade 2, mastec done
Excellent: According to adjuvant online (www.Adjuvantonline.Com), you have about an 82% 10 yr survival rate based on your specific information provided. This is only an estimate since there are details I do not have such as type of chemotherapy being used. For triple negative breast cancer, these survival rates are quite excellent. ...Read moreSee 1 more doctor answer
DCIS, left breast, biopsy itself removed high grade cancer cells, lumpectomy path 100% cancer free. Radiation necessary? What about proton therapy?
32 YO, triple positive, grade 3, stage 1B breast cancer. TCH chemotherphy, had dbl mastectomy. What is survival rate?
Need Clarification!: Are you sure your breast cancer was triple positive(or was it triple Negative)??? TCH is commonly used chemotherapy for triple negative, so please double check and let us know. Then we can give you survival figures. In general, small tumors(Stage 1 and stage 2) have very good survival rate and high cure rates. ...Read more
32 yo, breast cancer stage 1b, double mastectomy, micrometastasis in one lymph node. TCH treatment, followed by radiation. Prognosis thoughts????
Prognosis is good!: I would need more information to be definitive but with a small primary tumor (stage 1) and only micrometastasis in one node, your prognosis should be relatively good. Since you received TCH, it is obvious that you had her2 positive breast cancer so your prognosis is less favorable than had her2 not been positive. However, 5 year survival in excess of 85% is shown in recent studies with TCH. ...Read more
O had surgery for positive breast cancer. Is sentinel lymph node biopsy accurate for breast cancer surgery. Node was negative.
Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?
Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. and at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more
Herceptin (trastuzumab): Herceptin (trastuzumab) is approved for the treatment of early-stage breast cancer that is human epidermal growth factor receptor 2-positive (her2+) and has spread into the lymph nodes, or is her2+ and has not spread into the lymph nodes. If it has not spread into the lymph nodes, the cancer needs to be estrogen receptor/progesterone receptor (er/pr)-negative or have one high risk feature. ...Read moreSee 1 more doctor answer
No: A lymph node replaced with malignant cells growing as a primary lymphod tumor or metastatic from another site which has spread to axilla will not shrink without treatment, either chemo or RT. The node will enlarge further or if unchanged will spread to adjacent nodes. It does not have the potential to metastasize further to non lymphatic tissue such as liver or lung. ...Read moreSee 2 more doctor answers
My mom had lobular breast cancer at 52. Brca negative. Is lobular breast cancer more genetic based than ductal?
No its medullary: a quote from Lancethttp://www.ncbi.nlm.nih.gov/pubmed/9167459: "The occurrence of invasive lobular carcinoma and invasive ductal carcinoma was not significantly different between carriers of BRCA1 or BRCA2 mutations and controls. Medullary or atypical medullary carcinoma was, however, found more often in BRCA1 (13%, p ...Read more
Depends: Survival rates depend on multiple factors; age, response to treatment, stage of disease, your overall health. This is a conversation best had with your medical oncologist. ...Read more
Please clarify.: It is unclear from your question what you are asking. Most breast cancers are estrogen-sensitive and can be treated with anti-estrogen medication (tamoxifen, aromatase inhibitors). Many women who are peri menopausal when receiving traditional chemotherapy develop ovarian suppression from the chemo and effectively "go into" menopause. I hope this helps. ...Read more
Spread of cells: Micrometastasis means that a few tumor cells have left the breast tumor and traveled to the lymph nodes under the arm. In most cases, this is treated as a negative lymph node. I encourage you to review your pathology report with your surgeon and oncologists (ideally they are communicating with each other through a meeting called a tumor board). ...Read moreSee 3 more doctor answers
An organ, cell or molecule that accepts an outside signal and causes an internal change. Eyes receive light, touch receptors send messages to the brain when stimulated by pressure and estrogen receptors bind Estradiol causing responses of normal breast, ovary and uterus cells to rising and falling levels of the female steroid hormones. Most of the time "receptor" refers to one ...Read more
Most breast cancers are carcinomas. This is a type of breast cancer. These cancers start in the cells that line organs and tissues. In fact, breast cancers are often a type of carcinoma called adenocarcinoma, which starts in cells that make glands (glandular tissue). Breast adenocarcinomas start in the ducts (the milk ducts) or ...Read more
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