Doctor insights on:
Chemotherapy For Triple Negative Breast Cancer
What neoadjuvant chemotherapy treatment would you recommend for Triple Negative Breast Cancer, staged T1N0M0?
Ask your...: It would be much easier and most logical to ask your medical and surgical oncologists since they know more of your individual situation than anyone online and nowadays the care for malignancy is multi-disciplinary. There are not many oncologists around online. To make you abler to interact with doc, please peruse articles in http://formefirst.com/onLifeBasics.html. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
It depends: There are several chemotherapy options for stage 2a breast cancer. Characteristics of the patient and the cancer are required to make a decision on the type of chemotherapy (and whether chemotherapy is even necessary). Chemotherapy would be anywhere from about 8 weeks to a year (herceptin-or trastuzumab treatment, if recommended, requires a year of treatment). ...Read moreSee 1 more doctor answer
Is chemotherapy required for stage 1A IDC breast cancer, tumor size 1.1 cm, ER & PR positive, HER2 negative, nuclear grade 1. Patient is 42 years old.
Borderline call!: Your breast tumor is quite small, so it has >90% odds that it can be safely treated with surgery, without any chemotherapy required. You may ask your doctor for treating you with tamoxifen which is a antihormone type of medication, commonly used as the treatment for tumors that are ER positive. Good luck ...Read more
It depends: Chemo treats the whole body to kill cancer cells that may have escaped from the breast tumor. Sometimes chemo is used to shrink the breast tumor before surgery (neoadjuvant chemotherapy). Breast cancers that respond best to chemotherapy are those with a high ki-67 (proliferation rate), er negative, and/or her2 positive. ...Read moreSee 2 more doctor answers
Very effective: Chemo initially started with combinations like CMF and then changed to combinations of antibody plus chemo such as taxol plus Herceptin (trastuzumab). These drugs alone and in combination best used as a neoadjuvant prior to surgical resection or when at high risk in the adjuvant setting to prevent recurrence. Once metastasis happens, there can be chemo control but cure is rare. ...Read more
Many diff regimens: There are many different regimens utilizing multiple drugs and ranging 3-6 months. Common drugs are anthracyclines, taxanes, and Cytoxan (cyclophosphamide) in various combinations - acx4, tcx4(or 6), tac x 6, acx4 ->tx4, dose dense ac->t, weekly taxol. Other options/drugs can also be considered in the metastatic setting. A patient should seek a medical oncologist experience in breast to rec the best regimen. ...Read moreSee 1 more doctor answer
Maybe: As with most other cancers, it depends on many factors but it would be safe to say that in certain situations, chemo is an integral part of the treatment for breast cancer. You need to talk to an oncogist about it. The goals of therapy should justify the potential toxicity. Best regards. ...Read moreSee 1 more doctor answer
Very!: TAC stands for Taxotere, Adriamycin, (doxorubicin) and Cyclophosphamide. It is one of the strongest regimens for treating breast cancer, and some would say too strong. Depending on the type of breast cancer you have, or the stage, you might be able to receive a gentler regimen. If you want to know more, get a second opinion. ...Read more
Do support her: She may need your emotional support and other help. Go meet her and ask if you can help her with any probelms or issues of concern to her. She would appreciate your concern for her welfare and your offer to help her.Just the company of a good friend can be a big morale booster. ...Read moreSee 1 more doctor answer
It depends: It depends on the type of breast cancer. If positive for estrogen and/or Progesterone receptors ("er" and "pr") there are other options, though in some cases it may not be as good as taking these meds in conjunction with chemo. If stage 4 breast cancer, there are many clinical trials. Again, it depends on the cancer stage, and the markers er/pr, and her2 from the cancer specimen. ...Read moreSee 1 more doctor answer
I'm just wondering, if you opt out for chemotherapy for breast cancer what is the process you go through?
Not sure if 'opt: Out' means 'refuse' or 'decide to stop'. Either is a serious decision that requires discussion with 1 or more medical oncologists. The 'oncotype' process defines benefit and risk of chemo in some. However, depending on many factors (size, nodal status, receptors), the consequences vary. Perfect for second or third opinion. ...Read more
Please clarify.: It is unclear from your question what you are asking. Most breast cancers are estrogen-sensitive and can be treated with anti-estrogen medication (tamoxifen, aromatase inhibitors). Many women who are peri menopausal when receiving traditional chemotherapy develop ovarian suppression from the chemo and effectively "go into" menopause. I hope this helps. ...Read more
Depends: This depends on the type of breast cancer you have. Treatment is now individualized to the type of cancer, lymph node involvement and hormone status of the cancer cells. A special test called a oncotype DX can help determine if chemotherapy is beneficial or not but the cells have to have hormone receptors. I recommend speaking with your oncologist. Don't be afraid to get a 2nd opinion. ...Read moreSee 1 more doctor answer
Minor pricedure: Minor surgical procedure for insertion. Small chamber under the akin attached to a catheter that goes into a main vein. Oncologist or their nurse inserts a needle through the skin into the port to deliver the medications. No specific patient care needs. The port can be removed when no longer needed. ...Read more
"Options": The standard and recommended treatment in premenopausal patients would usually included chemotherapy and an anti-hormone regimen. Chemo is only used in about 15% of postmenopausal women, those who have hormone negative tumors. Radiation is used in breast sparing procedures, and is used to supplement mastectomy patients. If you are unsure, get a second oncological opinion. Good luck. ...Read more
Patients with advanced breast cancer,Has received chemotherapy,Is there any need for radiotherapy?
Most breast cancers are carcinomas. This is a type of breast cancer. These cancers start in the cells that line organs and tissues. In fact, breast cancers are often a type of carcinoma called adenocarcinoma, which starts in cells that make glands (glandular tissue). Breast adenocarcinomas start in the ducts (the milk ducts) or ...Read more
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