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Doctor insights on: Chemotherapy For Metastatic Colon Cancer

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Colon cancer chemo necessary?

Colon cancer chemo necessary?

Depends on stage: Chemotherapy is never used for stage 1 cancers (early). It is sometimes used in stage 2 cancers (early but more advanced than stage 1). Chemotherapy is definitely beneficial in stage 3 cancers (locally advanced) and in stage 4 cancers (distant spread). ...Read more

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Dr. Barry Rosen
4,369 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Is metastatic colon cancer curable?

Is metastatic colon cancer curable?

Possible: But less than 20% survive 5 years. Depends on where the metastases are and how numerous and size. Solitary liver mets without evidence elsewhere in the body can be cured with a liver resection. Diffuse mets to numerous body parts rarelyare curable. ...Read more

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Dysphagia and chemotherapy for colon cancer?

Dysphagia and chemotherapy for colon cancer?

It depends ... : Dysphagia is a common side effect with many chemo therapeutic regimens. Some treatments can decrease a patient's ability to fight off fungal and bacterial overgrowth in the mouth and digestive systems. The diagnosis of this isn't usually difficult and can in many cases be treated with medications. ...Read more

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Is metastic colon cancer spread to liver treatable?

Is metastic colon cancer spread to liver treatable?

Yes: NOT "curable" but definitely treatable...Direct perfusion anti-neoplastic drugs for one approach and possible immune therapy on the "horizon" ...A positive attitude is necessary and helpful.. METASTATIC .CANCER IS A CHRONIC DISEASE! ...Read more

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What is prognosis With chemotherapy for metastic colon Cancer ?

What is prognosis With chemotherapy for metastic colon
Cancer ?

So many variables: Too many variables to give you a pertinent answer. Consult your oncologist to help you with clinical decisions ...Read more

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Treatments for prostate cancer with bone metastasis?

Treatments for prostate cancer with bone metastasis?

Many: The first line of treatment for this is androgen deprivation. In addition, there are medicines which reduce the risk of fractures with Denosumab showing the most efficacy compared to zoledronic acid, however with some risk of significant side effects. For more extensive disease, a newer IV radium therapy has shown improved survival. Localized radiation can be effective for painful foci. ...Read more

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Is colon cancer curable?

Yes: Yes. Many people are cured with colon cancer. If found early surgery alone may be curable. If more advanced (eg, lymph node involvement or metastatic = spread to areas outside of colon), then chemotherapy may be needed. While less likely, even a few % of people with metastatic colon ca may be cured. ...Read more

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Is metastatic anal cancer terminal?

Is metastatic anal cancer terminal?

Unfortunately: Metastatic disease (also known as stage 4) is usually not curable by todays treatments. Although use of chemotherapy may improve survival and may rarely put someone into a temporary remission the disease usually returns or more often does not go away and eventually progresses and the patient will eventually succumb to it. ...Read more

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What is the normal dose for Xeloda (capecitabine) for stage IV metastatic colon cancer?

What is the normal dose for Xeloda (capecitabine) for stage IV metastatic colon cancer?

Individualize dose: Xeloda (capecitabine) can be used as a single agent to treat stage IV metastatic colorectal cancer. The usual dose is 1250 mg/m2 twice daily orally for 14 days, followed by a 7-day rest period for a total cycle time of 21 days. Adjuvant treatment is recommended for a total of 6 months (8 cycles). Doses may be altered for individual situations with reduced doses for patients with kidney problems. ...Read more

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Metastatic breast cancer usually spread to liver?

Metastatic breast cancer usually spread to liver?

It may: Breast cancer can metastascise to many organs. Regionally to the lymph nodes and distantly to other organs. More commonly to the bones, lung, liver, brain and other visceral structures in the abdomen or pelvis. ...Read more

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Dr. Craig Lum Dr. Lum
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What can prognosis b like for metastic colon cancer that chemotherapy oxyplatin and raltitrexed ?

Dr. Craig Lum Dr. Lum
1 doctor agreed:

Colon mets: Not having your chart and you in front of me makes it very hard to give you an accurate idea on prognosis. When chemo is started, that means your CA cells have gone beyond the boundaries which would have made txing it simple. The simpler the tx, the better the prgns. The harder the tx, the worse the prgns. On a positive note, f/u with your docs, stay faithful, and you might get a pleasant surprise ...Read more

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Which chemo therapy is most effective for KRAS mutant metastic colon cancer ?

Which chemo therapy is most effective for KRAS mutant metastic colon cancer ?

Same drugs as other: Same chemotherapy drugs are used for treating both types of colon cancer. The only difference is lack of benefit from EGFR inhibitors(Cetuximab and Panitumumab). Avastin (bevacizumab) also works in both types. I trust that you know there are 3 chemo drugs that are widely used(5FU or Capecitabine, Irinotecan and Oxaliplatin) ...Read more

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How effective is regorafenib for colon cancer mets?

How effective is regorafenib for colon cancer mets?

Depends: One study showed a response rate of 40%. "Response" in this context, means the tumor shrunk. It is rare for tumors to disappear on regorafenib. Clinical benefit depends to a great extent on the overall fitness of the patient (performance status), extent of disease, and number of prior therapies. Courage and faith, Marilyn994, and my best wishes for you. ...Read more

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Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further. ...Read more

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Prognosis for hormone refractory metastatic prostate cancer with pathological fracture?

Prostate cancer: This is an advanced stage of prostate cancer; the good news is there are many new drugs and treatments for men in this stage that have been shown to extend life; in this stage survival is extremely variable from months to years isn't impossible. ...Read more

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What can approx prognosis b for metastic colon cancer with chemotherapy ?

What kind of mets: it depends what kind of metastases we are talking about. if the spread to the lymph nodes, surgery and chemotherapy, and possible radiation therapy could be very helpful. if the spread to the liver the prognosis is less optimistic, unless the metastases are able to be resected. other metastases are less promising in spite of chemotherapy and radiation therapy .like bone and brain. ...Read more

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What is metastatic pancreatic cancer?

Moved to other organ: Metastatic pancreatic cancer is cancer that started in the pancreas and then moved to other organs. Most commonly it moves to the liver. It can spread throughout the body though. ...Read more

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Is brachytherapy helpful for a prostate cancer patient who has metastasized cancer cells?

Is brachytherapy helpful for a prostate cancer patient who has metastasized cancer cells?

No.: Brachytherapy is used in the treatment of localized prostate cancer, or cancer that has not spread outside of the prostate gland. If a patient has metastatic disease, treatments need to be systemic, with the aim of halting the growth & spread of the cancer throughout the body. These treatments include hormonal therapy, chemotherapy, and immunotherapy. Urologists & medical oncologists can help. ...Read more

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What is metastatic prostate cancer?

What is metastatic prostate cancer?

Metastasis: in general, metastasis refers to a cancer that has gone from the organ of origin to other parts of the body ...Read more

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Dr. Erik Borncamp
13 doctors shared insights

Colon (Definition)

The colon is another term for the large intestine. This is the final portion of the digestive system, responsible for absorbing water and storing stool before evacuation. It is divided into sections described as cecum; ascending, transverse, descending and ...Read more


Dr. Sheila Smith
12 doctors shared insights

Colonic (Definition)

This is a combining term referring to some condition, treatment or disease of the colon. Such as colonic enema, colonic ...Read more