Doctor insights on:
Chemo for --- ibc marginally successful. Then mastectomy, 7 lymph nodes positive. Now the surgeon wants rad, onc wants different chemo. Help!
Yes for rad: Definitely you should get an adjuvant radiation therapy following mastectomy. As per- chemo- if you get chemo first before surgery and unfortunately the response is only marginal- that indicates that your cancer is likely is resistant to chemo.So, adding more chemo post mastetcomy doubtfully will give you any benefit. Is this er+ or er-? If this is er+- then you should get aromatase inhibitor. ...Read more
Stage 2B idc breast cancer-neoadjuvant ... Had taxol/herceptin (trastuzumab) for 16wks. Now a/c chemo.. Is it risky to be without herceptin (trastuzumab) until surgery in jan?
Should be okay: You are receiving ac now and i think (and i hope) it should take care you cancer well --to shrink it down further- so you can have surgery in january. It is not safe to combine adriamyicn and Herceptin (trastuzumab) as it could give you significant problem with your heart. Once you are done with surgery- you will need Herceptin (trastuzumab) to be continued for 1 year. ...Read moreSee 3 more doctor answers
Stage 3 nsclc right lung and lymph nodes. Chemo did not work, surgery impossible. Having 13 sessions palliative radiotherapy. What is life expectancy?
Depends on chemo: The side effects of chemotherapy depend on the chemos involved. In general bone marrow suppression (bms) causing lower red blood cells (rbcs) with anemia, lowered wbcs with increased risk of infection, and lowerd platelets with increased risk of bleeding. Oxalipaltin ("o" in folfox) can cause numbness or cold induced nerve pain. Irinotecan ("i" in folfiri) causes diarrhea. Etc... ...Read moreSee 1 more doctor answer
Different drugs. : Chemotherapy for a hematologic cancer such as AML differs in the drugs & regimens from an epithelial cancer like prostatic carcinoma. AML typically uses Cytarabine and an anthracycline on a specific schedule. In prostate cancer, docetaxel and cabazitaxel are frequently used drugs. Of note, chemotherapy is not as common a treatment for prostate cancer, where hormonal therapy is often used. ...Read moreSee 1 more doctor answer
Pancreatic cancer, ampullary tumor. Whipple procedure. Spread to liver, not respectable. Chemo for 6 months and continuing. Prognosis?
Poor: While Whipple is the best approach for a primary pancreatic or ampullary lesion, the recurrence rate at 1-2 yrs is 90%. Chemo either of the FOLFIERI or Genciabine /Abraxane combo have limited effects on liver mets which in pancreas are not considered amenable to resection. There is an FDA protocol using specific monoclonals targeting pancreas that might be available but only after chemo failure ...Read more
Same drugs as other: Same chemotherapy drugs are used for treating both types of colon cancer. The only difference is lack of benefit from EGFR inhibitors(Cetuximab and Panitumumab). Avastin (bevacizumab) also works in both types. I trust that you know there are 3 chemo drugs that are widely used(5FU or Capecitabine, Irinotecan and Oxaliplatin) ...Read more
Best institution for experimental protocol to add to nexavar (sorafenib) for metastatic HCC - 34 yo Asian male, s/p omental resection?
My dad has stage IV colon cancer with advanced liver mets..inoperable,non curative,on chemo &now coughing a little blood..is the cancer advancing?
Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?
Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. and at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more
What can prognosis b like for metastic colon cancer that chemotherapy oxyplatin and raltitrexed ?
Colon mets: Not having your chart and you in front of me makes it very hard to give you an accurate idea on prognosis. When chemo is started, that means your CA cells have gone beyond the boundaries which would have made txing it simple. The simpler the tx, the better the prgns. The harder the tx, the worse the prgns. On a positive note, f/u with your docs, stay faithful, and you might get a pleasant surprise ...Read more
It can be cured: And you are likely on retuximab too. Please ask your doctor why thaey have not made clear what your chances are, and why you should be optimistic. ...Read more
Experts, might someone recommend nexavar (sorafenib) for a stage 4 inactive neuroendocrine pancreatic cancer patient?
Possibly: Stage 4 indicates that you have net at a site distant from the pancreas or regional lymph node, likely the liver. Not clear what you mean by"inactive", whether you mean it is stable or not secreting any substance. In any case, sorafenib (nexavar) is being tested in metastatic net in clinical trials (http://clinicaltrials.Gov/ct2/show/nct00131911) & (http://www.Ncbi.Nlm.Nih.Gov/pubmed/23475104). ...Read moreSee 1 more doctor answer
My dad has spine metastes frm primary prostate cancer, terminal, indefinate hormone therapy...Whats average prognosis please?
Depends how long: How long on hormones? If just started the cancer may respond for average of several years. If he was already on hormones for long time prognosis is worse months to a year or two using other option such as different drugs or chemotherapy. Not cureable at this point just delaying progression. Some are offering Provenge (sipuleucel-t) but it's new and not known how effective, this is a vaccine type of therapy. ...Read moreSee 2 more doctor answers
Up to 1 year's worth: Herceptin (trastuzumab) can be given together with initial chemotherapy for the first 4-6 months then subsequently by itself for a total of 1 year. If chemotherapy was given first without Herceptin (trastuzumab) then Herceptin (trastuzumab) can be given for a full year by itself. The usual cycle runs every 3 weeks (17-18 cycles in one full year). ...Read moreSee 1 more doctor answer