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Doctor insights on: Chemo Nerve Damage

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What is the best treatment to treat nerve pain from ongoing chemo? Is it possible to prevent permanent nerve damage?

What is the best treatment to treat nerve pain from ongoing chemo?  Is it possible to prevent permanent nerve damage?

Unclear: Unfortunately there is no clear way to prevent chemo-associated neuropathy. Some medications such as steroids, gabapentin/pregabalin, or antidepressants may be helpful. Vitamin supplementation with b-complex or folate (folic acid) may also be helpful. Your oncologist may have recommendations specific to your type of chemotherapy, and all supplements should be discussed before taking to avoid interactions. ...Read more

Dr. Olav Jaren
1,291 doctors shared insights

Nerve Damage (Definition)

A complete nerve transection will leave an area totally numb. The distribution of the numbers depends upon where the nerve was cut. A partial nerve injury may leave the area tingly or incompletely numb. Finally even if the nerve is not cut the swelling and bruising to the tea can affect the nerve as well. Usually we consider sharp penetrating injuries as likely having nerve lacerations when sensation is lost. A hand surgeon can examine the hand and pinpoint the site or extent of nerve injury and recommend ...Read more


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What are the symptoms of lung cancer that spread to the brain? I have nerve damage from lung lobectomy and still have cancer. Do not want chemo.

What are the symptoms of lung cancer that spread to the brain? I have nerve damage from lung lobectomy and still have cancer. Do not want chemo.

Varied Brain sympto: Brain metastases often cause headaches which are persistent and progressive such that you will need medication to relieve it. other symptoms are nausea and or vomiting, vision changes and sometimes seizures. Paralysis of arms or legs can occur but only rarely. If there is any such concern a Brain MRI is a good test to check your brain.Radiotherapy and steroids are a good treatment(instead of Chemo ...Read more

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What should I do to reduce the effects of neuropathy after chemo?

What should I do to reduce the effects of neuropathy after chemo?

Difficult to treat: However, nerve pain medications like Gabapentin or Lyrica (pregabalin) can be beneficial. Some medications that can also be used as anti-depressants, such as Cymbalta or Effexor can be used as well. Topical pain creams containing ketamine can be helpful in treating chemo induced polyneuropathy as well. ...Read more

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Can adriamycin (doxorubicin) (chemo) cause neuropathy?

Can adriamycin (doxorubicin) (chemo) cause neuropathy?

Yes: Doxorubicin (adriamycin (doxorubicin)) can indeed cause nerve damage, but not always the typical 'peripheral neuropathy' seen with other chemotherapy drugs. It affects the myelin sheath of nerve and ganglia and can cause 'ganglionopathy'. Symptoms include numbness/tingling in both the arms/hands and legs/feet (not just the feet). Other drugs given alongside adriamycin (doxorubicin) can add to the risk. ...Read more

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What chemotherapy induces peripheral neuropathy?

What chemotherapy induces peripheral neuropathy?

Some: There are some chemo that can give you peripheral neuropathy for instance taxane (docetaxel, paclitaxol), vinca alkaloids ( vincristine), platinum ( oxaliplatin, cisplatin, carboplatin) etc. ...Read more

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Oncologist told me to take sublingual b 12 for post chemo neuropathy. What dosage is recommended?

Oncologist told me to take sublingual b 12 for post chemo neuropathy. What dosage is recommended?

Ask your oncologist!: B12 does not help neuropathy due to chemotherapy. So unless your blood level of B12 is checked and found to be low, i would not advise you to take this medicine. ...Read more

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Will a taxane for chemo cause permanent peripheral neuropathy if hereditary pn in family? Any alternative to taxane?

Will a taxane for chemo cause permanent peripheral neuropathy if hereditary pn in family? Any alternative to taxane?

Depends: Taxanes may cause permanent neuropathy in any patient although uncommon. There is increased intolerance to taxanes and preexisting sensory neuropathy. Unless the individual is effected by hereditary neuropathy I am not aware of any data suggesting an increased risk just because the family is affected. Whether taxanes can be replaced depends on disease and for what purpose it is used. ...Read more

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Got neuropathy after chemo 5 yrs ago; gone in 3 mo. Bak 2 yrs ago & now. Neuro md said could return for lifetime. Worry or not? Neuro md or fp? Worse

Got neuropathy after chemo 5 yrs ago; gone in 3 mo. Bak 2 yrs ago & now. Neuro md said could return for lifetime. Worry or not? Neuro md or fp? Worse

Neuropathy: Fp could probably do just fine. They will probably try a medicine like neurontin, lyrica, (pregabalin) or cymbalta. There are others but these are the most common. If the pain is the same as before this is the route i would take. ...Read more

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What can be done for neuropathy in my feet after I had chemotherapy?

Medications: There are medications that can help - Neurontin (gabapentin) and Elavil to name two possibilities. There is also a modality known at "anodyne therapy" that some physical therapists offer that can also be beneficial. ...Read more

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Does gabapantin use have a goal? Is there a point where i'm cured of post chemo neuropathy?Can i take metanx with i t? Chemo 1999.Numb feet 3 years.

Does gabapantin use have a goal?  Is there a point where i'm cured of  post chemo neuropathy?Can i take metanx with i t? Chemo 1999.Numb feet 3 years.

Neuritic pain: Chemo damages nerves. They can die, recover fully, or partial recovery with dysesthesia. Gabapentin (neurontin) helps during recovery to reduce pain. Once recovery period is over medication rarely helps. You are well past recovery period. Gabapentin should not affect other meds. ...Read more

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Dr. Sam Markzar
758 doctors shared insights

Neuropraxia (Definition)

Neuropraxia is defined as a temporary loss of function of the nerve. Some nerves are purely sensory while others carry both sensory and motor fibers. Traumatic contusion injuries to nerves or nerve compressions can cause Neuropraxia. Sensory nerves like sural nerve in the leg or mixed sensory and motor nerves like the median and ulnar nerves in the forearm & hand ...Read more


Nerve (Definition)

The brain and spinal cord communicates with what is occurring in the internal organs and limbs by nerve fibers where are like electrical wires with insulation (myelin) and the "copper" (axon). Within brain and spinal cord these nerves connect to other nerves via synapses on both axons and dendrites. A nerve can carry information regarding sensations, and ...Read more