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Doctor insights on: Chemo Nail Loss Taxol

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Can you tell me about breastcancer, chemotherapy and experiences with Taxol (paclitaxel) ?

Can you tell me about breastcancer, chemotherapy and experiences with Taxol (paclitaxel) ?

Paclitaxel: Paclitaxel or Taxol (paclitaxel) is a micro tubule inhibitor. It has great activity in breast cancer. Side effects include low blood counts, hair loss, numbness and tingling which may persist despite stopping the drug. Typically given either weekly or every other week in breast cancer. It is mixed with a chemical called cremophor which can cause an allergic reaction so patients are monitored. ...Read more

Dr. Devon Webster
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Chemotherapy (Definition)

The term chemotherapy typically is used to describe using chemicals to treat ...Read more


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What is the role of Taxol (paclitaxel) in chemotherapy?

What is the role of Taxol (paclitaxel) in chemotherapy?

Kills cancer cells!: Taxol (paclitaxel) works by preventing cancer cells from reproducing themselves. In the picture you can see green "microtubules" that are pulling a cancer cell apart into two daughter cells. Taxol blocks microtubules, preventing them from being able to pull the cancer cell into two daughter cells. The cancer cell gets stuck trying to divide, and it dies. Taxol works for many cancer types. ...Read more

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I'm taking Taxol (paclitaxel) chemotherapy, my lips and skin are now drying out. What can I use to ease this problem?

I'm taking Taxol (paclitaxel) chemotherapy, my lips and skin are now drying out. What can I use to ease this problem?

Lips and skin: Pharmacists are, in my opinion, the best folks to help you select the best 'over the counter" creams for your lips and something else for your skin. If you decide to go that route please let me know how things are going. ...Read more

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Comp 16 weeks of taxol/herceptin .. diangosis with mult pe's recently and about to begin a/c chemo. Will this be possible with existing pe's in both lungs?

Comp 16 weeks of taxol/herceptin .. diangosis with mult pe's recently and about to begin a/c chemo. Will this be possible with existing pe's in both lungs?

Yes: You have obviously survived the bilateral pulmonary emboli. You didn't mention being on Coumadin (warfarin) or any blood thinner but you should be if you are not(speak to your doctor). Hopefully, most of the clot on your lungs has dissolved. If you can't be on blood thinners for some reason, you could have a filter placed in your vena cava. Having cancer is a risk factor for having blood clots and pes. ...Read more

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I have stage 4 tnbc before i was to start AC chemo my platelets were too low 85. Started Taxol (paclitaxel) for a week now my liver enzymes are too high 590 ?

I have stage 4 tnbc  before i was to start AC chemo my platelets were too low 85.  Started Taxol (paclitaxel) for a week now my liver enzymes are too high 590 ?

Further eval: If platelets were low before starting, il'd worry that you have spread to the bone marrow. In that case, you would get treatment anyway, no matter what the counts, in hopes of clearing the marrow. If your liver enzymes are high, there may be liver metastases. I don't know your'e whole story, but i would strongly consider treating with something like Carboplatin and abraxane. Also check her2 again. ...Read more

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AFTER taxol/A/C for breast cancer stage2,path result-Lympho vascular invasion-shouldn't chemo resolved this? What now?

AFTER taxol/A/C for breast cancer stage2,path result-Lympho vascular invasion-shouldn't chemo resolved this? What now?

Ask your oncologist!: You need to givel us more information...Did the tumor shrink on chemotherapy? How much. shrinkage? If the tumor did not shrink much, that is a bad sign. But if it reduced in size substantially then you are on the right track. But your oncologist can address your questions and guide you better. ...Read more

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Can the reoccurance of cervix cancer within pelvis be cured with chemo[carboplatin+taxol]?

Can the reoccurance of cervix cancer within pelvis be cured with chemo[carboplatin+taxol]?

Ask your Oncologist: This is a question patients often ask their oncologists when he/she recommends chemotherapy.. So you should ask and see the answer you get. Then we can also verify it for you, if needed. ...Read more

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Stage 2B idc breast cancer-neoadjuvant ... Had taxol/herceptin (trastuzumab) for 16wks. Now a/c chemo.. Is it risky to be without herceptin (trastuzumab) until surgery in jan?

Stage 2B idc breast cancer-neoadjuvant ... Had taxol/herceptin (trastuzumab) for 16wks. Now a/c chemo.. Is it risky to be without herceptin (trastuzumab) until surgery in jan?

Should be okay: You are receiving ac now and i think (and i hope) it should take care you cancer well --to shrink it down further- so you can have surgery in january. It is not safe to combine adriamyicn and Herceptin (trastuzumab) as it could give you significant problem with your heart. Once you are done with surgery- you will need Herceptin (trastuzumab) to be continued for 1 year. ...Read more

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Finished my last Taxol (paclitaxel) chemotherapy last week, having a side effect of my fingers swelling, swelling hurts, what can I do to stop the pain & swelling?

Finished my last Taxol (paclitaxel) chemotherapy last week, having a side effect of my fingers swelling, swelling hurts, what can I do to stop the pain & swelling?

Hand swelling and pain: This is most likely side effect of Taxol (paclitaxel). Some side effects of taxol (paclitaxel) are neuropathy which is damaging of the nerve fibers joint pains and sometimes swelling of extremities. Most of this side effects get better after stopping the treatment but the neuropathy sometimes persists and requires lifelong medications. Follow up with your oncologist and discuss this problem. ...Read more