Doctor insights on:
Chemo For Melanoma
Different drugs. : Chemotherapy for a hematologic cancer such as AML differs in the drugs & regimens from an epithelial cancer like prostatic carcinoma. AML typically uses Cytarabine and an anthracycline on a specific schedule. In prostate cancer, docetaxel and cabazitaxel are frequently used drugs. Of note, chemotherapy is not as common a treatment for prostate cancer, where hormonal therapy is often used. ...Read moreSee 1 more doctor answer
Yes: Yes. In general surgery is not useful for metastatic (spread) cancer. However in oligo (few) metastatic cancer -- especially for breast, colon, melanoma cancers patients may be rendered stage 4 ned (no evidence of disease). This may improve local control and symptoms, survival, and in a few cases even lead to cure. Removing the primary tumor (kidney) in renal cell carcinoma is helpful in met rcc. ...Read moreSee 1 more doctor answer
Individualize dose: Xeloda (capecitabine) can be used as a single agent to treat stage IV metastatic colorectal cancer. The usual dose is 1250 mg/m2 twice daily orally for 14 days, followed by a 7-day rest period for a total cycle time of 21 days. Adjuvant treatment is recommended for a total of 6 months (8 cycles). Doses may be altered for individual situations with reduced doses for patients with kidney problems. ...Read more
So many variables: Too many variables to give you a pertinent answer. Consult your oncologist to help you with clinical decisions ...Read more
Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?
Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. and at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more
What kind of mets: it depends what kind of metastases we are talking about. if the spread to the lymph nodes, surgery and chemotherapy, and possible radiation therapy could be very helpful. if the spread to the liver the prognosis is less optimistic, unless the metastases are able to be resected. other metastases are less promising in spite of chemotherapy and radiation therapy .like bone and brain. ...Read moreSee 1 more doctor answer
Depends: One study showed a response rate of 40%. "Response" in this context, means the tumor shrunk. It is rare for tumors to disappear on regorafenib. Clinical benefit depends to a great extent on the overall fitness of the patient (performance status), extent of disease, and number of prior therapies. Courage and faith, Marilyn994, and my best wishes for you. ...Read moreSee 1 more doctor answer
AFTER taxol/A/C for breast cancer stage2,path result-Lympho vascular invasion-shouldn't chemo resolved this? What now?
Ask your oncologist!: You need to givel us more information...Did the tumor shrink on chemotherapy? How much. shrinkage? If the tumor did not shrink much, that is a bad sign. But if it reduced in size substantially then you are on the right track. But your oncologist can address your questions and guide you better. ...Read more
Many: The first line of treatment for this is androgen deprivation. In addition, there are medicines which reduce the risk of fractures with Denosumab showing the most efficacy compared to zoledronic acid, however with some risk of significant side effects. For more extensive disease, a newer IV radium therapy has shown improved survival. Localized radiation can be effective for painful foci. ...Read moreSee 1 more doctor answer
Is it possible for stage three colorectal cancer to grow and spread during radiation and chemo treatments?
Yes it can do so: Cancer can and sometimes does grow/progress right through the given treatment. it happens when the Cancer cells are resistant to the chemotherapy which is the case in about half of colorectal cancer patients treated with chemotherapy. A change of treatment is then required as the new treatment(different drugs) may still have a chance to work on the cancer. Your oncologist can explain this better. ...Read moreSee 1 more doctor answer
What can prognosis b like for metastic colon cancer that chemotherapy oxyplatin and raltitrexed ?
Colon mets: Not having your chart and you in front of me makes it very hard to give you an accurate idea on prognosis. When chemo is started, that means your CA cells have gone beyond the boundaries which would have made txing it simple. The simpler the tx, the better the prgns. The harder the tx, the worse the prgns. On a positive note, f/u with your docs, stay faithful, and you might get a pleasant surprise ...Read more
Ciii ovarian cancer in 06, 1212, surgery and chemo paxitaxtel/carboplatin. In remission. Recurrence treated with tamoxifen, carboplatin alone, abraxan, then topotacan to no avail. Which chemo next?
Many options: Choosing chemo depends on many factors, so only your doctor can decide what might work for you. Drugs you haven't mentioned include altretamine, capecitabine, cytoxan, (cyclophosphamide) vinorelbine, ifosfamide, etoposide, and irinotecan. There are also several hormonal agents. And a clinical trial might be an option. Check out www.Cancer.Gov for more info. And good luck. ...Read moreSee 1 more doctor answer
Pancreatic cancer, ampullary tumor. Whipple procedure. Spread to liver, not respectable. Chemo for 6 months and continuing. Prognosis?
Poor: While Whipple is the best approach for a primary pancreatic or ampullary lesion, the recurrence rate at 1-2 yrs is 90%. Chemo either of the FOLFIERI or Genciabine /Abraxane combo have limited effects on liver mets which in pancreas are not considered amenable to resection. There is an FDA protocol using specific monoclonals targeting pancreas that might be available but only after chemo failure ...Read more