Doctor insights on:
Ciii ovarian cancer in 06, 1212, surgery and chemo paxitaxtel/carboplatin. In remission. Recurrence treated with tamoxifen, carboplatin alone, abraxan, then topotacan to no avail. Which chemo next?
Many options: Choosing chemo depends on many factors, so only your doctor can decide what might work for you. Drugs you haven't mentioned include altretamine, capecitabine, cytoxan, (cyclophosphamide) vinorelbine, ifosfamide, etoposide, and irinotecan. There are also several hormonal agents. And a clinical trial might be an option. Check out www.Cancer.Gov for more info. And good luck. ...Read moreSee 1 more doctor answer
IDC BC-HER2,PR,ER&LN positive,local skin met-LVI found AFTER CHEMO completed.
Recur risk?Prognosis?Avg time 2 reoccur? Dx@39
Yes: If a 2b lesion has been completely resected with a lobectomy and there is no problem 6 months post surgery the best approach is for careful follow up. Adjuvant radiation for this stage of disease has shown no survival benefit and adjuvant chemo if initiated following surgery has only shown a 5% improvement in survival. ...Read more
Stage 2B idc breast cancer-neoadjuvant ... Had taxol/herceptin (trastuzumab) for 16wks. Now a/c chemo.. Is it risky to be without herceptin (trastuzumab) until surgery in jan?
Should be okay: You are receiving ac now and i think (and i hope) it should take care you cancer well --to shrink it down further- so you can have surgery in january. It is not safe to combine adriamyicn and Herceptin (trastuzumab) as it could give you significant problem with your heart. Once you are done with surgery- you will need Herceptin (trastuzumab) to be continued for 1 year. ...Read moreSee 3 more doctor answers
Chemo for --- ibc marginally successful. Then mastectomy, 7 lymph nodes positive. Now the surgeon wants rad, onc wants different chemo. Help!
Yes for rad: Definitely you should get an adjuvant radiation therapy following mastectomy. As per- chemo- if you get chemo first before surgery and unfortunately the response is only marginal- that indicates that your cancer is likely is resistant to chemo.So, adding more chemo post mastetcomy doubtfully will give you any benefit. Is this er+ or er-? If this is er+- then you should get aromatase inhibitor. ...Read more
Modestly well: Your doctor can address this question better as I do not have details of your tumor sites and bulk of metastases. In general, chemo for metastatic Colon cancer is palliative which means it can be treated and kept under check for months/years but often not curable unless the tumor is amenable to surgical excision following a partial tumor regression with chemotherapy. Good luck. ...Read more
Chemotherpay failed , irinotecan and oxyplatin in metastic colon cancer . Liver and peritoneal mets . Is there anything else ?
Sorry to: hear that. Discuss with your Oncologist what is the next step. Get family and spiritual support as well. Good luck ...Read more
Oligodendroglioma, stage 3, 2 surgeries later growing, already tried radiation, now chemo. Are there alternatives?
No disrespect to: Anybody, but are you being treated by folks with expertise in CNS cancers? I'm not implying you have been poorly managed, i'm sure your docs are good competent guys, but at this point i would visit an academic cancer center with a neuro-oncology team and availability of clinical trials. Best to you. ...Read moreSee 1 more doctor answer
Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?
Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. and at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more
Chemotherapy irinotecan failed . Mcrc pt with few small mets u under 2 cm, can ablation such as nano knife be beneficial ?
Possibly: Technology still new without good long term data. Go to an institution that has a large experience, like a University Hospital ...Read more
Not often: Radiotherapy can be useful in certain select cases where the Cancer is localized to one or two spots only. This means 1 patient in 5 may be suitable candidate. But you need to seek consultation with a radiation oncologist before you can get a clear cut answer for your circumstances. ...Read moreSee 1 more doctor answer
AFTER taxol/A/C for breast cancer stage2,path result-Lympho vascular invasion-shouldn't chemo resolved this? What now?
Ask your oncologist!: You need to givel us more information...Did the tumor shrink on chemotherapy? How much. shrinkage? If the tumor did not shrink much, that is a bad sign. But if it reduced in size substantially then you are on the right track. But your oncologist can address your questions and guide you better. ...Read more
MAGIC MOUTHWASH: Mouth sores can be a sign that your white blood cells have dropped. Get labs drawn. For relief of symptoms while discomfort resolves several combinations exist. My favorite: nystatin/maalox/carafate - very soothing. Other include: benadryl/nystatin/maalox - can burn and viscous lidocaine/nystatin/maalox - will numb your entire mouth/tounge. ...Read moreSee 1 more doctor answer
Liver and peritoneal mets for mcrc patient . What is approx survival
With chemo , oxyplatin and raltitrexed ?
We can not guess: We can not tell you what the approx. survival as we do not have all the information to make a comment on the approx. survival You should discuss with your treating Oncologist There are second and third line treatments as well which may change the course ...Read more
What can prognosis b like for metastic colon cancer that chemotherapy oxyplatin and raltitrexed ?
Colon mets: Not having your chart and you in front of me makes it very hard to give you an accurate idea on prognosis. When chemo is started, that means your CA cells have gone beyond the boundaries which would have made txing it simple. The simpler the tx, the better the prgns. The harder the tx, the worse the prgns. On a positive note, f/u with your docs, stay faithful, and you might get a pleasant surprise ...Read more
Pancreatic cancer, ampullary tumor. Whipple procedure. Spread to liver, not respectable. Chemo for 6 months and continuing. Prognosis?
Poor: While Whipple is the best approach for a primary pancreatic or ampullary lesion, the recurrence rate at 1-2 yrs is 90%. Chemo either of the FOLFIERI or Genciabine /Abraxane combo have limited effects on liver mets which in pancreas are not considered amenable to resection. There is an FDA protocol using specific monoclonals targeting pancreas that might be available but only after chemo failure ...Read more
Some response: meds like Xeloda have some tempoary benefit suppressing DNA function as an oral 5FU (fluorouracil). Long term responses are not seen requiring combination therapy to give an optimjum response. Eventually if cancer does show a good response, malignant stem cells will repopulate the site of the original metastasis. ...Read more
Yes: Follow with your gyn oncologist regulrlyGet a more detailed answer ›
After undergoing surgery, chemotherapy, radiation, herceptin (trastuzumab) then hormonal treatment, how much more can my body tolerate?
Yes you can: Different chemos have the potential to cause death in many ways: low white cells leading to serious infections, low platelets causing bleeding, heart problems or kidney failure. It is not common to die of chemo side effects but as always, the benefit has to outweigh the risks everytime we use these drugs. ...Read moreSee 1 more doctor answer
"ports" are: Accessible devices under the skin that allow puncture and direct line to the venous system. It prevents multiple sticks and extravasation of caustic chemo outside veins. When chemo is completed, it should be removed. ...Read more
It depends: it depends on what kind of Cancer you have and what all has been done for you already. If the chemotherapy has been fully utilized, then it is good to switch over to Palliative care. Life support means different things to different folks. You should seek a palliative care specialist. ...Read more
It depends...: The potenial benefit of chemotherapy depends on the tumor type, biomarkers (eg, er/pr/her2 in breast cancer), stage, etc. For some diseases "calculators" can help determine the absolute risk reduction (as opposed to "relative" risk reduction). Some cancers may have limited benefit from chemo and others may benefit greatly. ...Read more
Pain from chemo?myth: When patients say they are fearful of pain from chemotherapy, they are generally misinformed by others. Chemo is medicine taken by injection or as pills. Just like any other medicine, there is no pain, other than when needle goes into the vein which is momentary only. So do not worry about it. let your oncologist and his/her staff teach you all that is expected, pain is not an expectation. ...Read more
Many have kids: It all depends on the chemotherapy regimen. Some chemotherapy has no affect on fertility, while other regimens will make someone infertile. For this latter case, sperm banking for men and egg preservation for women before chemotherapy is recommended. ...Read moreSee 1 more doctor answer
Immunotherapy trial: At some point chemotherapy fails in patients with met. colorectal Ca. The Ca stem cells in the tumor are resistant to all forms of chemo having DNA repair mechanisms for protection. Immunotherapy with Avastin, (bevacizumab) Erbitux and Neo-101 can help. The latter targets a post translational modification of MUC5ac that acts as an immunogen and is in FDA trails. A newer mAb Neo -201 is being produced. ...Read more
Supportive?: I do not understand your question. Do you mean supportive therapy as in Hospice care? When and if chemotherapy fails, a patient can opt to focus on comfort. This is a perfectly acceptable decision but should not be made in haste. If this is not what you were asking, please clarify. ...Read moreSee 1 more doctor answer
Wow: No way we can answer this. Infusion protocols vary depending on the chemo. Side effects also depend on the type of chemo and how sick the patient is to begin with. Your oncologist will be able to answer this better. Do remember, attitude is important. If you go to therapy convinced you will be sick, you WILL be sick. Hope you do very well. ...Read more
See specialist...: As previously stated, whether or not someone can still have children after receiving treatment for cancer depends on many factors. There are fertility doctors (ob/gyn) who now specialize in helping patients who are cancer survivors. I would advise you to seek one out, if possible. I wish you the best. ...Read moreSee 1 more doctor answer
Depends but best to: Chemotherapy refers to chemical therapies that go throughout the bloodstream. There are many different kinds and different cocktails are used for different tumors. Doses and specific drugs are tailored to the health of the patient. Some regimens are very easy to tolerate with only mild affect on blood counts while others are more difficult. It is always best to be as strong as u can in prep ...Read more