Doctor insights on:
Chemo Alternative To Taxol
Kills cancer cells!: Taxol (paclitaxel) works by preventing cancer cells from reproducing themselves. In the picture you can see green "microtubules" that are pulling a cancer cell apart into two daughter cells. Taxol blocks microtubules, preventing them from being able to pull the cancer cell into two daughter cells. The cancer cell gets stuck trying to divide, and it dies. Taxol works for many cancer types. ...Read more
Paclitaxel: Paclitaxel or Taxol (paclitaxel) is a micro tubule inhibitor. It has great activity in breast cancer. Side effects include low blood counts, hair loss, numbness and tingling which may persist despite stopping the drug. Typically given either weekly or every other week in breast cancer. It is mixed with a chemical called cremophor which can cause an allergic reaction so patients are monitored. ...Read more
Comp 16 weeks of taxol/herceptin .. diangosis with mult pe's recently and about to begin a/c chemo. Will this be possible with existing pe's in both lungs?
Yes: You have obviously survived the bilateral pulmonary emboli. You didn't mention being on Coumadin (warfarin) or any blood thinner but you should be if you are not(speak to your doctor). Hopefully, most of the clot on your lungs has dissolved. If you can't be on blood thinners for some reason, you could have a filter placed in your vena cava. Having cancer is a risk factor for having blood clots and pes. ...Read more
I have stage 4 tnbc before i was to start AC chemo my platelets were too low 85. Started Taxol (paclitaxel) for a week now my liver enzymes are too high 590 ?
If platelets were low before starting, il'd worry that you have spread to the bone marrow. In that case, you would get treatment anyway, no matter what the counts, in hopes of clearing the marrow. If your liver enzymes are high, there may be liver metastases.
I don't know your'e whole story, but i would strongly consider treating with something like Carboplatin and abraxane. Also check her2 again. ...Read more
AFTER taxol/A/C for breast cancer stage2,path result-Lympho vascular invasion-shouldn't chemo resolved this? What now?
Ask your oncologist!: You need to givel us more information...Did the tumor shrink on chemotherapy? How much. shrinkage? If the tumor did not shrink much, that is a bad sign. But if it reduced in size substantially then you are on the right track. But your oncologist can address your questions and guide you better. ...Read more
Stage 2B idc breast cancer-neoadjuvant ... Had taxol/herceptin (trastuzumab) for 16wks. Now a/c chemo.. Is it risky to be without herceptin (trastuzumab) until surgery in jan?
Should be okay: You are receiving ac now and i think (and i hope) it should take care you cancer well --to shrink it down further- so you can have surgery in january. It is not safe to combine adriamyicn and Herceptin (trastuzumab) as it could give you significant problem with your heart. Once you are done with surgery- you will need Herceptin (trastuzumab) to be continued for 1 year. ...Read more
Had an ultrasound that showed the liver to be slightly heterogeneous. Can that be due to past chemo therapy with Adriamycin, (doxorubicin) Cytoxan and Taxol?
I had breast cancer in March 2014, had red devil and taxol chemo for 6 months, had a mastectomy and 6 weeks of radiation. My period stopped in May 2014 due to chemo. I started bleeding yesterday which seemed like a period, is this normal?
Can be normal: Will be better to see your GP. Any underlying cause should be exclude. Eg papsmear to check cervix abnormalities ...Read more
I'm taking Taxol (paclitaxel) chemotherapy, my lips and skin are now drying out. What can I use to ease this problem?
Lips and skin:
Pharmacists are, in my opinion, the best folks to help you select the best 'over the counter" creams for your lips and something else for your skin.
If you decide to go that route please let me know how things are going. ...Read more
Finished my last Taxol (paclitaxel) chemotherapy last week, having a side effect of my fingers swelling, swelling hurts, what can I do to stop the pain & swelling?
Hand swelling and pain: This is most likely side effect of Taxol (paclitaxel). Some side effects of taxol (paclitaxel) are neuropathy which is damaging of the nerve fibers joint pains and sometimes swelling of extremities. Most of this side effects get better after stopping the treatment but the neuropathy sometimes persists and requires lifelong medications. Follow up with your oncologist and discuss this problem. ...Read more
Finished taking Taxol (paclitaxel) chemotherapy, hands and fingers swollen. What can I do for swelling to go away?
It will go away: All the changes in your skin and hair will go away in a short time after your last dose of Taxol (paclitaxel). Most patients are fully recovered in 3 to 6 months. So do not worry about the swelling...there is no treatment for it but your body are repair and normalize it slowly but surely. ...Read more
Currently taking Taxol (paclitaxel) chemotherapy, have a cold. Hurts to swallow, chest hurts when I cough. Is there anything I can do?
Take pain meds: You should report this problem to your oncologist and ask for medication for what appears to be virus/Flu type of sore throat. If your blood counts are not low, you could also use tylenol (acetaminophen) for pain control but make sure that you do not have fever. With low counts or Fever, tylenol (acetaminophen) is not safe unless your doctor is monitoring your condition. ...Read more
My mom is undergoing chemotherapy-currently taxol- for breast cancer-is neuropathy that comes and goes a normal side effect?
Taxol (paclitaxel): TAXOL (paclitaxel) is contraindicated in patients who have a history of hypersensitivity reactions to TAXOL (paclitaxel) or other drugs formulated in Cremophor® EL (polyoxyethylated castor oil). TAXOL (paclitaxel) should not be used in patients with solid tumors who have baseline neutrophil counts of ...Read more
Drug from a tree: Taxol is a chemotherapy drug used commonly to treat breast cancer. It's generic name is paclitaxel. It is also used to treat ovarian, lung, prostate, bladder, melanoma, esophageal cancer and other solid tumor cancers. It is made fromthe pacific yew tree bark. It works by preventing the cancer cells from dividing and therefore stops their growth. ...Read more
Discontinued: Taxol (paclitaxel) has been discontinued in the us. There was originally concern because of the environmental impact of its original sourcing, no longer used, from the pacific yew. In addition, the assignment of rights, and even the name itself, to bristol-myers squibb were the subject of public debate and congressional hearings. ...Read more
Stops cell division.: In order to grow and spread, cancer cells need to divide and make copies of themselves. In order to divide and make copies of itself, the cell must prepare by organizing a kind of internal scaffolding, called microtubules. Taxol (paclitaxel) works by preventing the microtubules from functioning properly. Consequently, the cells can't divide properly and cancer growth is slowed. ...Read more
Stops cell division: Taxol (paclitaxel) is a chemotherapeutic agent that act to arrest rapidly dividing cells such as cancer cells. As such, it can also impede certain "normal" cell division such as white blood cels. Cell counts must be monitored frequently during treatment with this agent. ...Read more
Not too many:
Taxol (paclitaxel) is contraindicated in patients who have a history of hypersensitivity reactions to Taxol (paclitaxel) or other drugs made in cremophor el (polyoxyethylated castor oil).
Taxol (paclitaxel) also should not be used in patients with solid tumors who have white counts of less than 1500 cells/mm3 or in patients with aids-related kaposi’s sarcoma with baseline white counts of less than 1000 cells/mm3. ...Read more
Taxol (paclitaxel) or Paclitaxel is a chemotheaputic drug which is used to treat a variety of cancers including lung, breast, ovarian and head and neck cancers.
It works by interfering with cell division.
It is produced by a fungus that lives in a south american tree bark. ...Read more
Half lives: For Taxol, the half-life is dependent upon the length of the infusion. If it is a three hour infusion, the half-life is approximately 24 hours, but for a 24 hour infusion, it is about 52 hours. For carboplatin, the retention half life can be as much as 30 hours. Hope that helps. ...Read more