Doctor insights on:
Chemical Formula For Cyclosporine
Needs monitoring: Cyclosporine is a calcineurin inhibitor and it has a narrow therapeutic index. If the blood level of cyclosporine is too high, it is likely to cause adverse effects which include nephrotoxicity, hyperlipidemia, gingival hyperplasia, and hair growth. Whether it is used as an anti-rejection agent or as an immunosuppressant in treating auto-immune diseases, one needs to have a close follow-up. ...Read more
See your prescriber: Cyclosporine is a very potent medication and requires careful attention to dosing and monitoring for side effects. You should contact the prescriber they will know a lot more about your specifics. ...Read more
None: No interactions found (medscape interaction checker)Get a more detailed answer ›
Hi, How long is the bioavailability of the cyclosporine once is outside the original package? Thank you
Pharmacist: Your pharmacist is very qualified to answer your question as he/she has up to date information on all medications. ...Read more
Have chronic hivee & have been put on cyclosporine. Just started taking the medication sat a.M. 200 mg a day. When can I expect to see some relief?
Unlikely: This is a difficult question to answer. Therapy for chronic urticaria can be antihistamines, one blockers, lipo oxygenase blockers, to name a few. I would reevaluate the Cyclosporine to consider alternative therapy. ...Read more
Different ways: While Cyclosporine is a very important medication used in the transplant field and in different rheumatologic and autoimmune diseases it sometimes may damage the kidneys by causing constriction of the vessels inside them. If you are concerned about potential side effects of this medication you should ask your prescribing physician about it. ...Read more
Last resort: Cyclosporine is an effective treatment for psoriasis - but it is usually used only when all else has failed, because it is toxic to the liver and kidneys, among other things, and weakens the immune system. It should never be taken without close monitoring by an expert in its use for that purpose (usually a dermatologist). ...Read more
Cyclosporine is an immunosuppressive agent. It is used to reduce the body's natural immunity in patients that receive organ transplants. It is also used to treat severe cases of psoriasis and rheumatoid arthritis.
It's very strong medication. It may cause side effects that could be serious, such as high blood pressure and kidney and liver problems. May also reduce the body's ability to fight infec. ...Read more
RxAssist Database: Talk to your physician about your drug costs. And, don't be reluctant to look at all possibilities for reducing your medication costs-including those from drug companies, community health centers, local social service programs or charitable programs. Visit www. Rxassist. Org to help find options. ...Read more
Renal tubular damage: Cyclosporine is an immune supressing medication used for renal transplant patients. Overtime, this potent medication especially when its levels are high can damage the tubular structure of the kidney. If you are concerned about its use, discuss this issue with your nephrologists or your transplant team. ...Read more
Last resort: Cyclosporine is an effective treatment for eczema - but it is usually used only when all else has failed, because it is toxic to the liver and kidneys, among other things, and weakens the immune system. It should never be taken without close monitoring by an expert in its use for that purpose (usually a dermatologist). ...Read more
Neoral (Cyclosporine) is an Immunosuppressive medication with a number of potential uses to include
prevention of transplanted organ rejection. ...Read more
Yes but....: Before using cyclosprorin, get tested for igg food sensitivities. Or at least try avoiding the most common food allergens for a few wks and then add back in slowly to determine what u r reacting to. The most common are wheat, all dairy products, corn, oats, soy, eggs. It can be any food. U need to do a yeast cleanse and start basic vitamins as well. I've treated many difficult cases w/success. ...Read more
Yes: Cyclosporine is a "second line" medication for hives. It is useful for chronic hives in people who will need long-term treatment, and has more side effects than the "first line" treatments such as antihistamines. It is only used when first line medications don't work - that is, when the benefits of the drug outweigh its risks. ...Read more
Relatively, yes: All drugs have potential side effects, some worse than others. Cyclosporine works well for its uses, but patients must be willing to work with doc closely to prevent untoward events, e.g. Reporting any side effects, reporting fever or infection immediately no matter how seemingly slight. Co-operate with doc when monitoring lab work is asked for; it's for your protection & well-being. ...Read more
Yes: Cyclosporin is a systemic medications used for severe psoriasis. It works quickly, but is toxic to the kidneys with long term use, so it is recommended that it be used for a limited period of time (6-12 months maximum). Generally it is used to get a patient through a short-term severe flare or to give rapid response while waiting for a slower acting medication like Methotrexate to "kick in". ...Read more
Severe cases.: In very severe cases Cyclosporine has been used. In most cases it is treated with prescription creams and oral steroids for brief periods. A recent report shows that vitamin d 1600 units is helpful for eczema. In over 60 per cent of eczema patient sublingual desentization can cause resolution of eczema over a 2 year period. ...Read more
While both used. ...: For gvhd prophylaxis, they are completely different drugs with distinct mechanisms of action. Methotrexate is a dihydrofolate reductase inhibitor that inhibits 1-carbon metabolism needed to make nucleotides. Csa binds cyclophillin to block an intracellular phosphatase (pp2a), and in so doing, blocks nuclear translocation of nfat (a transcription factor), preventing il2 synthesis and immune fxn. ...Read more
No: However, safe is a relative question, when this medication is used. Usually, Cyclosporine is used to suppress rejection in transplants. It can also be used for severe autoimmune problems. Therefore, the safety is felt to be greater than the danger without it. But it can cause convulsions, peptic ulcers, pancreatitis, fever, vomiting, diarrhea, confusion, liver and kidney failure. ...Read more
Systemic vesrsus: Eye drops? Not in the same league as concentration! ...Read more
Cyclosporine: Cyclosporine is a immunosuppressant drug, not a immunotherapy. Immunosuppressant suppresses your immune system ; is used in organ transplant to suppress rejection. It is also used in some autoimmune diseases like rheumatoid arthritis, psoriasis. Immunotherapy means differently. Allergy immunotherapy uses allergens that you are allergic to in order to desensitize you from that allergen. ...Read more
Psoriasis: It is used for psoriasis, not hives. For hives the cause should be identified. If otc antihistamines do. Ot work, then oral antihistamines, tagamet, (cimetidine) or a combination can be used to suppress hives. For resistant cases, Colchicine or oral steroids are used on occasion. ...Read more
My husband is taking cyclosporine/immunosuppressive medicine long-term, could that cause birth deffects on a fetus/baby?
What is exactly the interaction between ginger tea and cyclosporine modified, increase just the side effects or increases concentration plasma?
Rather decrease: In its plasma concentration, ginger isn't recommended to use while on oral cyclosporine modified, ginger reduces the bioavailability of the drug and reduce blood level concentration, an effect you don't want especially in post transplant patients for fear of organ rejection, the studies were mostly on rats but the results and recommendations are valid for humans, goodluck ...Read more
Surgery last resort: Optimal management of uc requires a good coop effort among your primary doctor, gastroenterologist and surgeon. Both immuno suppressant and biological as you mentioned have their roles in dz management. Though surgery can cure uc, it is usually the last option as it has it's own complication and will change your life forever. ...Read more
Liver toxicity: The biggest risk would be liver toxicity. ...Read more
Can my fetus be more susceptible to infection or disease if I am taking an immunosuppressive like cyclosporine?
No: Very minimal amounts of Cyclosporine actually cross the placenta. Your baby should not be at any increased risk of infection. There have been reports of an increased risk of preterm delivery and smaller babies. Some of that may be related to whatever condition the woman was on Cyclosporine for. ...Read more