Doctor insights on:
Cf (Cystic Fibrosis)
Progressive disease: Cystic fibrosis (CF) is a progressive, lifelong condition in which the glands that produce mucus, sweat, and intestinal secretions do not function properly. Thick mucus accumulates in the lungs, leading to breathing difficulty and infection. CF also impairs digestion, and affected males are usually infertile. ...Read moreSee 1 more doctor answer
Can men with atypical cystic fibrosis have children? I have 2 children, I have no symptoms of CF and I am 32 years old. Never tested for CF.
My son has hirschsprung disease. My wife tested neg. for cystic fibrosis. Are the two related? Should I be tested for CF? I'm 32 w/no issues.
No, not related: Hirschsprung's disease is a congenital condition that leads to absence or lower numbers of nerve cells in the large intestine that are responsible for allowing the colon muscles to function, leading to constipation or inability to pass stool. Cystic fibrosis is an inherited recessive disorder of salt transport leading to thickened secretions. If your wife is negative, no need for you to be tested ...Read moreSee 2 more doctor answers
Newborn boy has a severe mutation delf508 and a 5-t gt12. Was told that he might or might not develop mild cystic fibrosis. How does mild CF manifest?
Varies: Mild CF can vary from recurrent sinus infections, recurrent pneumonia, pancreatitis, fertility problems. One may have no evidence of CF until adulthood. Sometimes the first sign is recurrent pancreatitis in the second or third decade of life. Usually growth is not impaired. ...Read moreSee 1 more doctor answer
My wife & son passed california newborn screening for CF, does that mean odds are low for typical cystic fibrosis or mild form?
Newborn screening : for Cystic Fibrosis is done by Immunoreactive Trypsinogen, IRT. If othe IRT level is ^, DNA tests for CF gene mutations are done on blood on the Guthrie card. CF Foundation-accredited Care Centers in CA look for an "intermediate" sweat chloride result in young infants who do not gain wt. & have bad gas, abdominal pain & loose or hard stools &/or wheezing/coughing for > 2 wks. to diagnose CRMS. ...Read more
Should I be tested for cystic fibrosis? If wife had negative prenatal screening & my son had negative IRT/DNA test (california screening). Curious after reading about CF in adults. Feel fine. anxiety
My son & wife tested neg for Cystic Fibrosis through screening test, not sweat test. However my son has hirschsprung disease. Should I test for CF - or it's high unlikely I have it? I'm 32. Feel fine
I wouldn't: There is no relationship between Hirschprung disease and CF. If you wand to know if you are an asymptomatic carrier of CF, the tests are available. However, you don't get to age 30 without symptoms when you have the disease and your fertility would also be diminished.If your wife is not a carrier, you can not produce babies with CF. ...Read moreSee 3 more doctor answers
My 3 1/2 yr. Old with cystic fibrosis has cold/ allergy symptoms...But unusually grumpy and purple color under eyes...Allergies or CF exacerbation?
Pls see answer: There is an overlap between the symptoms of allergy and cf. Allergic symptoms tend to be associated with a particular exposure that triggers an allergic response. The discoloration under the eyes may be caused by allergies, infection, lack of sleep, iron deficiency. If the area around the eye is red and swollen, it is best to check with your doctor. Fever > 101 is not usual for an allergic resp, . ...Read moreSee 1 more doctor answer
Certainly: Cystic Fibrosis (CF) most common life-limiting genetic disorder of Caucasians, affecting approximately 30K people in the US.A, impacting mainly respiratory function. In recent years patients symptoms better controlled by genetic findings and better medications.Emotional & phys. development depend on severity, time in hospital, complications.Morb. & mort.factors afect emotional,cognitive behavior. ...Read more
As a carrier: Genetic carrier testing: more than 10 million americans are symptomless carriers of the defective CF gene. This blood test can help detect carriers, who could pass CF onto their children. To have cystic fibrosis, a child must inherit one copy of the defective CF gene from each parent. ...Read more
Yes: Yes it is possible. Presentation of cystic fibrosis varies greatly, and it is possible, depending on your specific mutation (and other factors) to present at a later age. In order to prevent late diagnoses, all states now have a newborn screen in place for cystic fibrosis. ...Read moreSee 1 more doctor answer
I have family members with cystic fibrosis. Is it possible to start show the symptoms in my 20's?
What are the chances of a child getting cystic fibrosis among the different racial groups in the u.S.?
Overall 1/3700: Acording to the CF foundation: the overall birth prevalence is 1/3700 . It can occur in any race, however the greatest incidence is in caucasians of northern european descent, being 1/2500. The other major groups affected are hispanics 1/13500, african americans 1/15000. More than 10 million of us carry one part of the defective gene, but to have the disease you must have a copy from both parents. ...Read moreSee 1 more doctor answer
Genetic disorder: It is a genetic disorder characterized by abnormal sodium channels, which affect a great deal of problems including the respiratory and digestive systems. It is most commonly diagnosed in infants failing to gain appropriate weight, and in children who have multiple chronic infections. ...Read moreSee 1 more doctor answer