Doctor insights on:
Cervical Cancer Higher Remission Taxol
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?
Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. and at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more
Sometimes: There is a familial disorder known as lynch syndrome which increases both the risk of colon cancer and endometrial (uterine) cancer. About 5% of all colon cancers are caused by lynch syndrome. If a family has multiple cases of both colon and endometrial cancer or colon cancer under the age of 40, lynch syndrome should be considered. ...Read moreSee 1 more doctor answer
A little bit: Yes, but not a great deal. The good news is that surveillance for any skin cancer is the same. Examine your own skin regularly, and keep your scheduled appointments with your doctor or dermatologist. Notify them if you see any lesions which are concerning for skin cancer. Best wishes! ...Read moreSee 2 more doctor answers
Ciii ovarian cancer in 06, 1212, surgery and chemo paxitaxtel/carboplatin. In remission. Recurrence treated with tamoxifen, carboplatin alone, abraxan, then topotacan to no avail. Which chemo next?
Many options: Choosing chemo depends on many factors, so only your doctor can decide what might work for you. Drugs you haven't mentioned include altretamine, capecitabine, cytoxan, (cyclophosphamide) vinorelbine, ifosfamide, etoposide, and irinotecan. There are also several hormonal agents. And a clinical trial might be an option. Check out www.Cancer.Gov for more info. And good luck. ...Read moreSee 1 more doctor answer
Varies: This varies dramatically depending on the stage. Small tumors confined to the kidney may be curable in 90% or more of people, whereas lymph node involvement or involvement of tissues surrounding the kidney may be curable in only a small percentage of people. ...Read more
Low but not zero: Stage ii colon cancer means no lymph node involvement by definition, but inadequate lymph node sampling (surgical resection) may "understage" the cancer, so make sure enough ln were taken -minimum of 12! even with appropriate surgery, mets may still occur, although very unusual, so discuss with your treating docs. A pet/ct may give some reassurance so ask if this can be done. ...Read moreSee 1 more doctor answer
Yes: It improves survival significantly in stage 1-3 lung cancers. Cyberknife provides survival similar to surgery in stage 1 patients. For stage 2-3 patients, both chemo and radiation may be used to improve survival. In certain patients with stage 4 cancer (such as with spread to the brain) radiation may help improve survival. ...Read moreSee 2 more doctor answers
Also called by its: Generic name, vinorelbine, it is a mitotic spindle inhibitor, and the new "v" drug added in the 1990's. It enjoys a prominent role in nsclc lung cancer treatment in canada and some european countires (france, italy), but not used commonly in us. Now Pemetrexed dominant in most adenocarcinoma, free-for all in squamous. Data using nav in post op (anita trial) reliable. Paclitaxel dominant usa. ...Read moreSee 1 more doctor answer
Will avastin (bevacizumab) increase survival significantly for metastic colon cancer with liver mets ?
Is it a risky drug
Slight benefit: Bevacizumab (Avastin (bevacizumab)) is one of those drugs that is extremely expensive and often has limited benefit. Patients with metastatic colon cancer who received Avastin (bevacizumab) plus chemotherapy lived 1-2 months longer on average than those receiving chemo only. Because it has marginal benefit but costs ~$30,000 the U.K. Health Service won't pay for it. It can cause skin rash, bleeding or wound healing problems. ...Read more
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