Doctor insights on:
Cervical Cancer And Tamoxifen
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Sort Of: We define cancers by their organ of origin. Therefore, by strict definition, bone cancer originates from bone cells; Anastrozole won't help these rare cancers. More commonly, cancers can spread to bones--we call this bone metastasis. Breast cancer can spread to bones; anastrazole can prevent the spread of certain breast cancers. Hope this helps. ...Read more
Yes. like ERT: The increase risk is similar to that of unopposed estrogen replacement therapy. It is important that all your doctors (esp your gyn in this case) are aware what medications you're taking and report any irregular vaginal bleeding/discharge or other pelvic symptoms. ...Read moreSee 1 more doctor answer
Sometimes: There is a familial disorder known as lynch syndrome which increases both the risk of colon cancer and endometrial (uterine) cancer. About 5% of all colon cancers are caused by lynch syndrome. If a family has multiple cases of both colon and endometrial cancer or colon cancer under the age of 40, lynch syndrome should be considered. ...Read moreSee 1 more doctor answer
Yes: Tamoxifen has been shown to increase the risk of uterine cancer, not unlike estrogen replacement therapy, with an incidence of ~1:500. However, this is almost-always caught at its earliest stage, with very high cure rates. If you compare the benefit of tamoxifen for either treating or preventing breast cancer compared to this risk, the benefit far outweighs the risk. ...Read moreSee 1 more doctor answer
Yes: The chance is about 1% and treatment is hysterectomy. With such a low chance then tamoxifen is worth the risk. A gynecologist needs to keep track of the patient and any unusual bleeding evaluated. There are also other hormone alternatives with less risk. Check with your medical oncologist to see which drug is best for a particular patient. ...Read moreSee 1 more doctor answer
Chemotherapy: Tamoxifen is a very effective drug for the treatment of hormone-sensitive (estrogen receptor +) breast cancers. It may be used alone or in combination with traditional IV chemotherapy, depending on the cancer stage. Furthermore, tamoxifen has been shown to be effective reducing the chance of developing breast cancer in high-risk women ("chemoprevention"). ...Read moreSee 1 more doctor answer
Are uterine cancer, endometrial / ovarian cancer, and uterine fibroids/other abnormalities detected through pap smear other than cervical cancer?
No.: Pap smears sample cervical cells only.Get a more detailed answer ›
Is arimidex (anastrozole) when given as prevention of recurrence of breast cancer only used with estrogen receptive cancer?
Yes*: Arimidex (anastrozole) belongs to a category of drugs called aromatase inhibitors. These are effective chemotherapeutic agents for people with either estrogen-sensitive or *progesterone-sensitive breast cancers. This is only effective after menopause; premenopausal women may use tamoxifen for a similar response rate. ...Read moreSee 1 more doctor answer
Cervical cancer and endomitroese runs in my family. My question is cervical cancer and endomitriosis hereditary?
Not directly usually: There is debate about how closely these 2 cancers are related. Both have hereditary natures and are more common generally in obese patients. Both often begin with more benign precursor lesions like dcis for breast cancer and benign polyps for colon cancer. Both are very common but there is little evidence that having either predisposes to having the other. ...Read moreSee 2 more doctor answers
Would metastatic cervical cancer in the breast appear the same as breast cancer on mammogram and ultrasound?
Possibly on imaging: Cervical cancer (the tissue at the end of the vaginal canal) rarely metastasizes to the breast. Rather breast cancer may metastasize to many areas of body, such as bone, lung, brain, lymph nodes. That being said, any abnormal growth in the breast, though mostly breast tissue, could look similarly by mammogram or ultrasound. The bottom line is if there is an abnormality, must be biopsied. ...Read moreSee 2 more doctor answers
Essentially yes.: This is basically the term for uterine cancer as endometrial cancer comprises most of the cancers in the uterus. There can be myometrial cancer, or cancer of the muscular layer of the uterus, and also leiomyoma/fibroid tumor, another benign tumor in the muscle layer of the uterus that has malignant variants, but these would be specified in diagnosis. But, overall, this is usually what it means. ...Read moreSee 2 more doctor answers
It can.: The most definitive study that looked at uterine cancer rates associated with tamoxifen found that women had twice the risk of developing uterine cancer, at a rate of 1 per 500 women per year. This rate is far lower than the rate of breast cancer prevention; thus, the benefits far outweigh the risks. A better alternative after menopause is aromatase inhibitors, which do not increase this risk. ...Read moreSee 1 more doctor answer
This medication is used to: treat breast cancer that has spread to other parts of the body in men and women. Treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy. Reduce the risk of developing a more serious type of breast cancer in women who have had ductal carcinoma in situ (dcis; a type of breast cancer ...Read more
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