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Doctor insights on: Ceruloplasmin

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Dr. Jean Fox
56 doctors shared insights

Ceruloplasmin (Overview)

Ceruloplasmin is an enzyme in the body that does the majority of the copper transport in the blood stream. Copper is a vital element for iron metabolism in the human body.


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For what reason serum cu and ceruloplasmin levels are paradoxically low in wilson's disease?

For what reason serum cu and ceruloplasmin levels are paradoxically low in wilson's disease?

Not paradoxical: The problem is that copper can't get out of certain cells. The reason for ceruloplasmin being low is under study; since it carries copper, this metal also tends to be low. Checking serum copper and serum ceruloplasmin as a screen for wilson's misses up to a quarter of cases, especially if the person is already sick with anything. ...Read more

Dr. Jean Fox
56 doctors shared insights

Ceruloplasmin (Overview)

Ceruloplasmin is an enzyme in the body that does the majority of the copper transport in the blood stream. Copper is a vital element for iron metabolism in the human body.


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Why are cu and ceruloplasmin levels paradoxically low in wilson's disease?

Why are cu and ceruloplasmin levels paradoxically low in wilson's disease?

Minor mystery: Copper is low because ceruloplasmin is low; most copper in the blood is carried on the protein. Nobody really knows why ceruloplasmin tends to be low in Wilson's, and I hope that you also know that in about 30% of Wilson's patients it is not low at all, making is a very poor screening test. ...Read more

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Blood work for eye pain, palate tremor. Ceruloplasmin low 15. Wbc borderline 4.7, phosphate alkaline bl 44. Ast 20 ALT 22. Possible cause? 23 yrs old

Blood work for eye pain, palate tremor. Ceruloplasmin low 15. Wbc borderline 4.7, phosphate alkaline bl 44. Ast 20 ALT 22. Possible cause? 23 yrs old

Blood tests ok: Your blood test results are within normal limits. These do not provide an explanation for your symptoms. All lab results need to be interpreted in the clinical context and usually the doctor who ordered the test is in the best position to do that. It would be prudent to see a doctor for an in-person evaluation. ...Read more

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Low ceruloplasmin (.19) what does it meean?

Copper: Ceruloplasmin is involved in copper transport (which we need in certain chemical functions in the body). If the ceruloplasmin is low then you could have a disorder called Wilson's disease. This disease is not diagnosed with 1 blood test so you need to see your doctor and finish the workup. ...Read more

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Does a normal serum copper level and serum ceruloplasmin level of 21 rule out wilson's disease? Have fatty liver with zero risk factors & mansymptoms

No: Diagnosing wilson's is treacherous and i'd ask about a urinary copper. About 1/4 of wilson's patients will have normal serum ceruloplasmin, and the serum copper is even less reliable. ...Read more

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Low ceruloplasmin (.19) what does it meean?

Copper: Ceruloplasmin is involved in copper transport (which we need in certain chemical functions in the body). If the ceruloplasmin is low then you could have a disorder called Wilson's disease. This disease is not diagnosed with 1 blood test so you need to see your doctor and finish the workup. ...Read more

See 1 more doctor answer
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What is the definition or description of: ceruloplasmin?

What is the definition or description of: ceruloplasmin?

Copper enzyme: Ceruloplasmin is an enzyme in the body that does the majority of the copper transport in the blood stream. Copper is a vital element for iron metabolism in the human body. ...Read more

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Why are cu and ceruloplasmin levels paradoxically low in wilson's disease?

Minor mystery: Copper is low because ceruloplasmin is low; most copper in the blood is carried on the protein. Nobody really knows why ceruloplasmin tends to be low in Wilson's, and I hope that you also know that in about 30% of Wilson's patients it is not low at all, making is a very poor screening test. ...Read more

See 1 more doctor answer
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Why would I need a serum ceruloplasmin measurement?

Wilson's Disease: This test is ordered when checking for wilson's disease, a condition of copper overload. The overload of copper can lead to cirrhosis, nerve damage, or even mental illness. ...Read more