Doctor insights on:
Centrilobular Necrosis Of The Liver
How bad is a focal area suggestiv of central fibrosis within liver. Mild centrilobular cholestasis and attached fibroadiposed tissue with fat necrosis?
Depends: It is impossible to evaluate these findings without knowing the clinical setting and the results of other tests of liver function. Certainly this does not make me suspect liver cancer. If you have questions about this ultrasound finding, I would ask your doctor or your gastroenterologist. Good luck. ...Read more
This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more
What's the cause?: An elite athlete can kill off huge numbers of his liver cells in a prolonged endurance event and they grow right back with the liver restored perfectly. This also happens after prolonged shock with recovery. If you have a chronic hepatitis (viral, immune) with ongoing cell damage, the outcome is whatever is expected for the hepatitis. Insist your physician tell you what's killing liver cells. ...Read more
Serious problem: You may be referring to a problem of either fatty liver infiltration or liver disease secondary to a condition like pre eclampsia. Either way, the process leads to an elevation in blood tests that reflect damage to liver cells due to an underlying process. This is a serious problem and needs to be addressed as to the underlying cause. If it goes untreated it can lead to more serious consequence. ...Read more
My wife liver fibrous scor 3/6
Spotty necrosis score 3/4
Prominent interface hepatitis score 4/4
Is this advanced stage need to transplant ?
See doctor : A decision like this needs appointment to doctor. ...Read more
Iam 63 old have soft tisse mass in descedig colon measres 67*42*38 mm with focal liver lesion in rt lobe
show adeno carcinoma with necrosis?
Colon mass: Cheryl, this is difficult to answer. If you have a biopsy diagnosis of colorectal carcinoma, then the liver lesion may represent a metastasis. It could also represent only a liver hemangioma. Only a liver biopsy of the lesion is definitive. Red cell tagging studies sometimes can be definitive noninvasive study for liver hemangioma but does not have 100% sensitivity and may give false negative. ...Read more
For patients with multiple large neuroendocrine liver metases with unknown primary and no treatment, what does it mean when the hepatic masses are starting to display necrosis (cystic changes)?
Loss of viability: When tumors metastasize to the liver, their surface glycoproteins determines that they grow only in a liver ferritin substrate and cant metastasize elsewhere. The lesion will grow since its main blood supply is hepatic artery where liver parenchyma is fed by the portal system. As the lesion enlarges , the hepatic blood supply is unable to reach the center of the tumor and necrosis appears ...Read more
I had breast cancer 5 years back now liver shows newly developed hypodense focal lesions with minimal necrotic changes?
If both hepatic portal vein and hepatic arteries have thrombosis how long would it take for the liver to become necrotic ?
Liver ischemia: There are 2 blood supplies to the liver. The portal vein which supplies about 80% and the hepatic artery which supplies about 20%. If both are occluded the liver can become ischemic and die. This can happen right away. If one is occluded in one of the larger branches though blood can find other routs to get to the liver tissue. Also, the thrombus may recannalize and some blood may get through. ...Read moreSee 1 more doctor answer
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