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Doctor insights on: Celiac Disease Panel Blood Test

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How accurate is the blood test for celiac disease?

How accurate is the blood test for celiac disease?

Not very : It is perhaps about 50% accurate. We believe it when positive but not when negative. Even biopsy can miss the diagnosis. Best to test celiac genetic panel. Mayo lab and enterolab can do this. Google enterolab and order the test yourself $150. ...Read more

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Dr. John Chiu
603 doctors shared insights

Celiac Disease (Definition)

In celiac disease, the body reacts to gluten (in wheat and gluten-like proteins in rye and barley) resulting in damage to the small intestine. This limits the intestine's ability to absorb some nutrients. Typically, people with celiac disease have loose stools, bloating, abdominal pain or discomfort, weight loss, poor weight gain ...Read more


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Can celiac disease be 100% ruled out with the blood test?

Can celiac disease be 100% ruled out with the blood test?

Yes: If genetic markers (DQ 4, 8) are negative and there is not antibody to gliadin peptide, celiac disease can be ruled out. ...Read more

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My endoscopy biopsy looked exactly like something caused by Celiac disease but my blood test came back negative, what else could it be?

My endoscopy biopsy looked exactly like something caused by Celiac disease but my blood test came back negative, what else could it be?

Biopsy definitive.: In regards to celiac disease, the biopsy is more diagnostically reliable than the blood test, so if the blood test showed typical evidence of celiac disease, I'd believe it. ...Read more

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Is it possible for a toddlers blood test to be negative for celiac disease but upon endoscopy or colonoscopy be found to indeed have celiac disease?

Is it possible for a toddlers blood test to be negative for celiac disease but upon endoscopy or colonoscopy be found to indeed have celiac disease?

Possibly: If the correct test was done (measurement of IgA antibody to human recombinant TTG is recommended for initial testing for CD by NASPGHAN) and was negative, AND if a child has chronic diarrhea or failure to thrive OR if they have selective IgA deficiency or a + family hx of CD, a biopsy might be recommended. Consult with a pediatric GI physician if this is the case. Best of luck! ...Read more

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I have not checked for Celiac disease. Should I get a blood test? I have been under a lot of stress lately. I also drink a lot of caffeine.

Maybe: Your question does not provide enough info to confirm or exclude need for a celiac screening. It is a real problem with some subtle symptoms and effects. Screening is simple but confirmation requires an intestinal biopsy.You should have it confirmed before trying a gluten free lifestyle, which has a cult like following. True celiacs have other associated risks that need to be explored. ...Read more