Doctor insights on:
Cea W Hama Treatment
Cea is rising 1 point per month while on irinotecan . Does this mean not responding to treatment ?
CEA often fluctuates: We have to give 2 months of chemo before we can assess response. CEA is not enirely reliabnle unless you have done it 3-4 times in a row, one month aprt. Then it will show us a trend for tumor being better or worse. Yet we rely much more on Imaging studies(CT scan etc) along with patient symptoms and doctor's examination. All together(these 4 items) will help us conclude if tumor is getting small ...Read moreSee 1 more doctor answer
A CEA rise upon starting irinotecan in person with colon cancer suggest treatment not working ? Cea was
Oct 8, dec 9, jan 10.
Very good question!: The answer's somewhat debated. 1st, CEA levels even in the presence of cancer r somewhat variable, so my 1st question is *how much* did the values rise? An increase of 1 mcg/L may not b significant, though an increase of 100 mcg/L is definitely so. Also, levels increase if u r around cigarette smoke. Lastly, CEA could be released from cancer cells as they die. TTYD (Oncologist) to interpret numbrs ...Read more
Colon cancer patient . Cea rising on irinotecan . It was started in oct when CEA was 8. Dec cea-9, jan CEA 10. Is this treatment failure ?
Not necessarily: Chemotherapy can cause the CEA to rise when started. In addition, that is not a significant rise to make me concerned. Also, one wants to see a trend. Meaning, 8, 10, 15, 20 before one thinks failure. In addition, don't treat a number, treat what can be seen on the CT scan. Hope this helps. ...Read more