Doctor insights on:
Causes Symptoms Of Pernicious Anemia
Early IDA possible: Hypochromic suggests low iron (which can be measured by ferritin, transferrin, etc). Usually this would be from blood loss. Usually iron deficiency anemia (ida) is also assoc w/ microcytic (low mcv) red blood cells (rbcs). It depends on the numbers, other tests & history, but could be early iron deficiency/blood loss &/or more than one process -- eg b12/folate deficiency & ida. See md. ...Read more
Autoimmune disease: Pernicious anemia is an autoimmune disease producing autoantibodies against intrinsic factor found in the lining of the stomach. This leads to lack of absorption of vitamin B12 which is important in making blood cells and for nourishment of the nervous system. Treatment would be by replacement of B12 via injections or absorption into the body by other means (nasal spray). ...Read more
Not usually: Microcytic anemia is usually due to iron deficiency, rather than hypothyroidism. If associated with hypothyroidism, anemia is usually macrocytic (often secondary to pernicious anemia). Either way, an anemia deserves a thorough workup with your medical doctor, and treatment of your hypothyroidism. Best wishes! ...Read moreSee 1 more doctor answer
Anything: Headaches can come from fatigue, sleeping too much or too little, eye strain, sleep apnea, snoring, being dehydrated, having chronic sinusitis or allergies, too much caffeine or over the counter headache medication, high blood pressure or something more serious like a tumor. See your doctor and get checked. ...Read more
Not clear: No clear evidence for the causal-effect relationship between the two. PA is an autoimmue-mediated destruction of parietal cells in stomach, resuling in impairmnent of B12 absorption. Certainly it is possible that pernicious anemia may co-exist or exacerbate duodenitis via immune process or loss of balance in duodenal fluid, or anemia. But the causal-effect relationship is not well established. ...Read moreSee 1 more doctor answer
No: Bit both should be worked up.Get a more detailed answer ›
Many: There are many causes for anemia (RBC), just list a few: 1) decreased production due to not enough nutrition, B12/folate/iron def, or bone marrow diseases or bone marrow suppression from drugs/radiations or due to chronic kidney disease (not enough epoietin); 2) increased destruction: intravascular or extravascular hemolysis; 3) blood loss or chronic disease/cancer or some congenital diseases. ...Read more
Symptoms of SS: The altered shape of the red blood cells causes them to stack up together and clog blood vessels, depriving the tissues of adequate blood supply and oxygen. The tissues then die (infarct) and this causes pain. The red cells also rupture or are eaten by the spleen and cause anemia. The spleen itself will gradually infarct, leaving the patient susceptible to infections. ...Read more
Yes: Aplastic anemia is a failure of your bone marrow red cell production. The blood count drops, you lose energy, have trouble doing anything and if neglected the level could go so low that you cannot function and might even die. Bone marrow transplantation offers a very successful remedy. You should consult with your hematologist about this. ...Read moreSee 1 more doctor answer
Indirectly...: If the iron deficiency is severe enough, iron deficiency anemia will result. With this anemia, there is less hemoglobin to carry the oxygen molecules to the tissues and this will cause shortness of breath. See your doctor for diagnosis and treatment of iron deficiency anemia. ...Read moreSee 1 more doctor answer
Most likely.....: Folic acid, or possibly B12 in the setting of deficient but not completely absent intrinsic factor synthesis. The eqivalent of pernicious anemia can be caused by inadequate B12 intake, inadequate intrinsic factor production by parietal cells (autoimmune destruction, atrophic gastritis, etc.) or inadequate absorption at the terminal ileum (also for many reasons). Some other rare reasons as well. ...Read more
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