Doctor insights on:
Causes Of Upper Motor Neuron Lesion
What are the symptoms and signs of the upper motor neuron lesion (cortex, internal capsule, brainstem, spinal cord) ?
Lesion Localization: The upper motor neurons also called “Cortical Motor Neurons” are located in the motor cortex of the brain. The the spinal motor neurons are the lower motor neurons. Signs of UMN is a stiffness and resistance to movement. Signs of LMN damage include weakness, muscle atrophy. Hope it helps. ...Read more
Higher brain centers: Babies normally have babinski responses but lose it as they mature. The response remains deep in the brain and spinal cord but is suppressed by the higher brain centers. If the higher brain centers become damaged, these primitive responses return because they are no longer being suppressed. Hope this helps to simplify the prior excellent answer. ...Read moreSee 1 more doctor answer
EMG of upper and lower limbs showing mild neurogenic changes from bilateral L2-L3 innervation means what?
Fairly nonspecific: These findings don't suggest anything specific, but of course it would depend on the actual values of the nerve conduction studies and the findings on EMG. You should discuss this with the ordering health care provider, since they may have been looking for something specific. ...Read more
ALS: Yes, in some individuals there does seem to be a prevalence for one versus the other. At least at the beginning of the disease. As it progresses both upper and lower are progressively destroyed. Within ALS I wouldn't call it a rare finding. Its more related to the precision of the diagnostic findings by individual neurologists and overall timing. ...Read moreSee 1 more doctor answer
What is the difference between an EMG/NCV of a patient with upper motor neuron disorder, and another with lower motor neuron disorde?
PNS versus CNS: Electromyography & nerve conduction studies evaluate the peripheral nervous system (PNS), of which lower motor neurons are part. Upper motor neurons belong to the central nervous system (CNS) & must be evaluated by other means. Someone with an upper motor neuron disorder will have normal or nonspecific EMG/NCV findings, whereas someone with a lower motor neuron disorder will have abnormal EMG/NCS. ...Read more
Impaired cranial nn: Cranial nerves 9 - 12. Are usually affected in bulbar palsy (a lower motor neuron disease, as compared to pseudobulbar palsy, which i just discussed). Again, there are multiple causes, different ones though. Common symptoms can afftect speech (dysarthria), swallowing (dysphagia), choke on liquids, voice problem (dysphonia). Aspiration of food or fluids can lead to pneumonia and death. ...Read more
How to differentiate between upper motor neuron disorder and lower motor neuron disorder in a 10 months old, if MRI isn't possible?
EMG: If a MRI is impossible then an EMG can demonstrate lower motor neuron dysfunction- (i.e. any abnormality involving the anterior horn cell, dorsal and ventral ganglia, peripheral nerve root, and/or muscle. In a 10 month old sedation may be required and will not effect the outcome of the test other than the patients cooperation and comfort. Take care and well wishes. ...Read moreSee 1 more doctor answer
What happens if the upper motor neurons are damaged wouldn't that result in lower motor neuron weakness?
Weakness: Motor neuron diseases affect the nerves that send the impulse to muscles to initiate movement. Examples of motor neuron diseases include lou gerig's disease(als) and spinal muscular atrophy. Symptoms may include limb weakness, difficulty swallowing, and difficulty breathing. Some types may also affect eye movement and facial expression. ...Read moreSee 1 more doctor answer
Extensor respons: The presence of a Babinski sign suggests an upper motor neuron lesion, although in infants the presence of the dorsiflexion of the great toe with plantar stimulation can be normal. Simplifying, it's thought by some it may be related to the difference between the anatomical flexors behaving differently, more as extensors. Medicine Decoded has a reasonable explanation of this. ...Read more
Neurologist: The physical exam findings will be more difficult to see, but a neurologist will be able to examine the patient and might elect to do testing such as an EMG which tests the conduction of the nerves. ...Read more
EEG finding: I assume you received this as part of an EEG report. This is not specific but can relate to a localized difference within the functioning of that part of the brain. Sometimes those findings are associated with seizures, but not always. You should follow up with the ordering physician to have further discussions about the finding. ...Read more
What are the causes for clonus hyperreflexia in both arms and legs. MRI shows no signs of MS or neuron impairment?
MRI only tells: .. part of the story. If you have myoclonus and hyper-reflexia, you must establish a strong relationship with a good neurologist in order to get diagnosed and treated as soon as possible. North of the equator, there are several devastating neurological disorders that cause these symptoms, multiple sclerosis being only one of them. Please get yourself diagnosed quickly. ...Read more
Regarding left primary motor cortex to biceps femoris, what type of information is relayed between these regions?
There are many-: -you think of contracting the muscle subconsciously brain sends impulse to muscle proprioception receptors lets the brain know where the leg is in time & space.feed back lets brain know how hard you need it to contract. All is close to the speed of light.all this info goes back & forth instantaneously. It's much more complicated but excluding electrolytes involved takes a book. ...Read moreSee 1 more doctor answer
What regions of the basal ganglia might, if inhibited, result in alleviation of Parkinson's disease symptoms?
Constant painless calf muscle twitches is it associated with hiv infection e.g. peripheral neurological types symptom that affect muscles and nerves ?
Not really...: Neuropathy and twitching are two different things which are not necessarily linked together. Symptoms of neuropathy include numbness in feet, burning sensation, problem with balance, etc. Twitching on the other hand can happen from a lot of different reasons such as stress, benign fasciculations or with more serious pathology involving the anterior horn cells such as ALS, Polio, etc. ...Read more
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