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Doctor insights on: Causes Of Toxic Granulation

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What is toxic granulation on cbc?

What is toxic granulation on cbc?

Powered-up neuts: When there's serious bacterial infection, or the body think there is, neutrophilic white blood cells will be produced that are extra-powerful. One sign is that the granules are easier to see. ...Read more

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What does the blood test mean when it says cytoplasmic vacuolation, toxic granulation, micro 2+? The segs are46 lymph37 mono10 abs mono1.1 child is 2

What does the blood test mean when it says cytoplasmic vacuolation, toxic granulation, micro 2+?
The segs are46
lymph37
mono10 
abs mono1.1 child is 2

Lab tests: These results can occur when the white blood cells are eating foreign material, which they are meant to do. Unfortunately these have little if any significance divorced from the clinical issues which prompted their being ordered. This should be discussed with the doctor. Good luck. ...Read more

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I had blood work done today, and was told i had toxic granulation in lungs and ordered for xray.. I now feel not on left upper side of back.. Scared!?

I had blood work done today, and was told i had toxic granulation in lungs and ordered for xray.. I now feel not on left upper side of back.. Scared!?

Neutrophils: We use the term toxic granulation when we see some of your blood cells very active trying to fight "something". Usually the cells are fighting bacteria or other organisms. But, there are cases of other substances that can activate your immune system to react thus making the cells look very "active" under teh microscope. The cxr will help your doctor identify the cause of why the cells are activ. ...Read more

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In ICU Jan 2016 - toxic granulation, NRBC .3, atyp lymphs 6%. No diagnosis. May 2017 admitted w/ naus/vom. WBC 3.4, RBC 3.6, hgb 8. Any link?

In ICU Jan 2016 - toxic granulation, NRBC .3, atyp lymphs 6%. No diagnosis. May 2017 admitted w/ naus/vom. WBC 3.4, RBC 3.6, hgb 8. Any link?

Not relevant: The link if any with your 2016 admission may not be relevant. You are anemic and that needs to be investigated, along with your other symptoms. It is not feasible to provide a meaningful opinion without taking additional history, physical examination and may be some tests. It would be prudent to see your doctor. Wish you good health! ...Read more

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Normal blood count with blood smear leukocyte; particles of toxic granulation, atypical cells lenfomo nuclear, one cell view of downey. Male, 58 ?

Normal blood count with blood smear leukocyte; particles of toxic granulation, atypical cells lenfomo nuclear, one cell view of downey. Male, 58 ?

Typical cell: This is a typical cell type (both the lymphocytes with toxic granulation and the Downey cell, which similar is a lymphocyte with features consistent with activation). These occur in the context of infection or stress when the lymphocytes are receiving "danger" signals. Can't comment conclusively without knowing more about the clinical situation, but not likely something that needs follow up. ...Read more

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SLIDE REVIEW results, anisocytosis 1+,microcytes 1+,normochromic,ovalocytes occasional,toxic granulation 2+,toxic vacuoles 1+,large platelet 1+Whado?

SLIDE REVIEW results, anisocytosis 1+,microcytes 1+,normochromic,ovalocytes occasional,toxic granulation 2+,toxic vacuoles 1+,large platelet 1+Whado?

Clinical picture: The real question is, how do you feel? These findings, while abnormal, may never be explained. In isolation, apart from the clinical picture, they are meaningless. I trust the reader is a pathologist or hematologist -- I'm the former, and often remind people that labs, while indispensable, are adjuncts to the clinical findings. ...Read more

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A full CBC shows toxic granulation, also sepsis in bowel,yet subsequent bloods no toxic granulation,is that cos of bloods maybe not being full CBC ?

A full CBC shows toxic granulation,   also sepsis in bowel,yet subsequent bloods no toxic granulation,is that cos of bloods maybe not being full CBC ?

Not clear: A CBC does not show "sepsis in bowel". If you had sepsis when the toxic granulation was picked up, that's to be expected, and I'm pleased that you have recovered. Perhaps there is a misunderstanding. And from time to time, "toxic granulation" can be an over-read by the technician or pathologist. ...Read more

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1 y/o fever x 2days (tmax 104). CBC after abx for ear infection was completed showed slight toxic granulation. Is this a concern?

1 y/o fever x 2days (tmax 104). CBC after abx for ear infection was completed showed slight toxic granulation.  Is this a concern?

What's WBC count?: Toxic granulation associated with infection mean your child's body is reacting to an infection. If the wbc is over 15,000 after two days of antibiotics I would be concerned that the treatment isn't working. Stay in close touch with your MD especially if your child worsens. Make sure getting lots of water and rest. Seek ER if changes in mental status, worsening symptoms like rash while with fever. ...Read more