Doctor insights on:
Causes Of Toxic Granulation
If I'm correct, toxic granulation in blood can b from sepsis, wat other issues can cause toxic granulation wit a predominant left shift of neutrophils?
Correct: Toxic granulations is a non-specific findings, usually associated with infections. ...Read more
Powered-up neuts: When there's serious bacterial infection, or the body think there is, neutrophilic white blood cells will be produced that are extra-powerful. One sign is that the granules are easier to see. ...Read more
What does the blood test mean when it says cytoplasmic vacuolation, toxic granulation, micro 2+? The segs are46 lymph37 mono10 abs mono1.1 child is 2
Lab tests: These results can occur when the white blood cells are eating foreign material, which they are meant to do. Unfortunately these have little if any significance divorced from the clinical issues which prompted their being ordered. This should be discussed with the doctor. Good luck. ...Read more
I had blood work done today, and was told I had toxic granulation in lungs and ordered for xray. I now feel not on left upper side of back. Scared!?
Neutrophils: We use the term toxic granulation when we see some of your blood cells very active trying to fight "something". Usually the cells are fighting bacteria or other organisms. But, there are cases of other substances that can activate your immune system to react thus making the cells look very "active" under teh microscope. The cxr will help your doctor identify the cause of why the cells are activ. ...Read more
In ICU Jan 2016 - toxic granulation, NRBC. 3, atyp lymphs 6%. No diagnosis. May 2017 admitted w/ naus/vom. WBC 3.4, RBC 3.6, hgb 8. Any link?
The link if any with your 2016 admission may not be relevant. You are anemic and that needs to be investigated, along with your other symptoms. It is not feasible to provide a meaningful opinion without taking additional history, physical examination and may be some tests. It would be prudent to see your doctor.
Wish you good health! ...Read more
Normal blood count with blood smear leukocyte; particles of toxic granulation, atypical cells lenfomo nuclear, one cell view of downey. Male, 58?
Typical cell: This is a typical cell type (both the lymphocytes with toxic granulation and the Downey cell, which similar is a lymphocyte with features consistent with activation). These occur in the context of infection or stress when the lymphocytes are receiving "danger" signals. Can't comment conclusively without knowing more about the clinical situation, but not likely something that needs follow up. ...Read more
SLIDE REVIEW results, anisocytosis 1+, microcytes 1+, normochromic, ovalocytes occasional, toxic granulation 2+, toxic vacuoles 1+, large platelet 1+Whado?
Clinical picture: The real question is, how do you feel? These findings, while abnormal, may never be explained. In isolation, apart from the clinical picture, they are meaningless. I trust the reader is a pathologist or hematologist -- I'm the former, and often remind people that labs, while indispensable, are adjuncts to the clinical findings. ...Read more
A full CBC shows toxic granulation, also sepsis in bowel, yet subsequent bloods no toxic granulation, is that cos of bloods maybe not being full CBC?
Not clear: A CBC does not show "sepsis in bowel". If you had sepsis when the toxic granulation was picked up, that's to be expected, and I'm pleased that you have recovered. Perhaps there is a misunderstanding. And from time to time, "toxic granulation" can be an over-read by the technician or pathologist. ...Read more
1 y/o fever x 2days (tmax 104). CBC after abx for ear infection was completed showed slight toxic granulation. Is this a concern?
What's WBC count?: Toxic granulation associated with infection mean your child's body is reacting to an infection. If the wbc is over 15, 000 after two days of antibiotics I would be concerned that the treatment isn't working. Stay in close touch with your MD especially if your child worsens. Make sure getting lots of water and rest. Seek ER if changes in mental status, worsening symptoms like rash while with fever. ...Read more
Possible infection: Sherry, "toxic granulation" refers to the appearance of the white blood cells seen when your doctor does a blood count. This finding is associated with several things but could indicate you are having an infection of some type. It is not a serious finding and you should not be worried if you have this. ...Read more
What does neutrophils show toxic granulations and band forms and ovalocytes & poikilocytis 1+ indicate?
Should I be worried if my child is frequently sick and the blood tests show cytoplasmic vac, toxic granulations, micro 2+. Her lymp is slightly low.
Sick child: I think of all abnormalities you listed, the most important is "frequently sick" child. The other abnormalities are referred to a blood test but are not specific for any particular disease and could be just a spot check abnormalities. The fact your child gets sick frequently needs to be investigated and other work up may be needed. Talk to your child doctor about that. Don't get fixed on 1 test. ...Read more
No, usually not: Leukocytosis is an abnormally high number of white blood cells in the blood, as measured on a blood test. Both viral and bacterial infections can sometimes cause high numbers of white blood cells (wbc's) or low numbers of wbc's (leukopenia). Unusual leukocytosis, not caused by an infection, can be due to a bone marrow problem such as an early stage of leukemia. A doctor can further evaluate. ...Read more
Titanium should not: Titanium should not cause reactions. It's used in various types of implants and is not toxic, especially if it is very pure titanium. Perhaps some people who are very allergic to metals could have reactions to nickel, which might be in "titanium" that is not pure. ...Read more
Uncommon: There was a particular type tampon that allowed a particular bacteria to grow rapidly in the vagina. That bacteria produced a toxin that cause "toxic shock". That tampon was removed from the market decades ago. In over 22 years of practice, I have never seen a case of toxic shock. ...Read more
Pancreas: Probably pancreas. This organ contains a large number of enzymes that are specifically designed to digest proteins, fats and carbohydrates. That is precisely what we are made of. Injuring the pancreas may releases all these evil humours into the local area. This can wreak havoc in your abdomen... ...Read more
Don't know what you: Mean by "toxic, " because actually, benzodiazepines have very little "toxicity" as we define it. Many drugs can cause stomach and intestinal inflammation, liver damage, heart damage, fluid retention, reduce the immune system, cause severe rashes - benzodiazepines have essentially none of these (allergy is always possible). They cause physical dependency and can cause addiction, and memory problems ...Read more
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