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Doctor insights on: Causes Of Subcutaneous Nodules

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Subcutaneous (Definition)

The hypodermis, also called the hypoderm, subcutaneous tissue, subcutis, or superficial fascia, is the lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome ...Read more


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Can hard subcutaneous nodules(around 1 CM each)on lower legs, that slightly itch and blackened skin and slight swelling of legs be symptoms of cancer?

Can hard subcutaneous nodules(around 1 CM each)on lower legs, that slightly itch and blackened skin and slight swelling of legs be symptoms of cancer?

There are many: Types of cancer but in your age group i would not jump to that conclusion? You likely had two sebaceous cysts or someting benign. Get seen but cancer is very low probability. Good luck. ...Read more

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Can subcutaneous nodules(around 1 cm) on lower legs that slightly itch wid little swelling and blackening(purplish)of skin on legs be signs of cancer?

Can subcutaneous nodules(around 1 cm) on lower legs that slightly itch wid little swelling and blackening(purplish)of skin on legs be signs of cancer?

Let's biopsy: I'm actually more concerned about a cryoglobulin or leukocytoclastic vasculitis. If you have been offered a biopsy, by all means go for it. This does not sound like erythema nodosum, but i've learned not to try to second-guess a rash / skin eruption without seeing it. ...Read more

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When do subcutaneous nodules appear in a patient with rheumatoid arthritis?

When do subcutaneous nodules appear in a patient with rheumatoid arthritis?

Anytime/often later: Rheumatoid nodules occur in about 35% of RA patients. Interestingly, smoking and the use of Methotrexate increases the risk of developing these nodules. They tend to appear later in the disease course but can occur really at any time. ...Read more

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How to know when do subcutaneous nodules appear in course of ra(rheumatoid arthritis)?

How to know when do subcutaneous nodules appear in course of ra(rheumatoid arthritis)?

Usually never: Subcutaneous nodules are only present in about 20% of cases, they are usually associated with more severe disease. ...Read more

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If I am having skin nodules can this be caused by cystic acne?

If I am having skin nodules can this be caused by cystic acne?

Cysts : Cystic acne appears as red, tender under the skin bumps . See a dermatologist for proper diagnosis and treatment. ...Read more

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My sister has skin nodules and the doctors don't know what they are. What can we do?

My sister has skin nodules and the doctors don't know what they are. What can we do?

University: Make appointment with university dermatologist. They have access to many colleagues in the department and world wide. May be they can help. ...Read more

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My gf has skin nodules and the doctors don't know what they are. Who should she see?

My gf has skin nodules and the doctors don't know what they are. Who should she see?

A dermatologist: A dermatologist may be able to diagnose these nodules based on appearance; if the appearance is not diagnostic, a skin biopsy can be done to make a definitive diagnosis. ...Read more

Nodule (Definition)

Any growth or deposit in the body or on its surface may be casually termed a nodule until its character is determined by the familiarity of the physician with it or by the results of a biopsy if it is not so obvious. The term is casual ...Read more


Dr. Mark Ingerman
23 doctors shared insights

Skin Nodules (Definition)

Subcutaneous nodules are raised skin lesions that originate in the subcutaneous layer, so are ...Read more