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Doctor insights on: Causes Of Spleen Enlargement

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Dr. Heidi Fowler
195 doctors shared insights

Enlarged Spleen (Definition)

An enlarged spleen is a clinical finding in which the spleen is larger than in a normal, healthy person. This can occur with infections, diseases of ...Read more


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3 yr old TPN dependent for 2 yrs. She has splenomegaly (measured 8.9) alt/ast looks great. Can TPN cause spleen enlargement w/out affecting liver?

3 yr old TPN dependent for 2 yrs. She has splenomegaly (measured 8.9) alt/ast looks great. Can TPN cause spleen enlargement w/out affecting liver?

Doubtful, but: I have never seen TPN cause isolated splenomegaly without some involvement of the liver, but i would defer the final answer to a peds GI doc. However, i would be more concerned that whatever underlying condition that is causing her to be TPN dependent and not able to use her gut is contributing to her splenomegaly, and not the TPN itself. ...Read more

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Is it possible for galbladder disease to cause spleen or liver enlargement?

Is it possible for galbladder disease to cause spleen or liver enlargement?

No: There would be no association of the gallbladder that i can think of that would cause liver damage to the point of liver enlargement, cirrhosis, or spleen enlargement. ...Read more

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What are the disadvantages of spleen enlargement ?

Several effects: Splenomegaly is an enlargement of the spleen. The spleen usually lies in the left upper quadrant of the human abdomen. In early stages, mild enlargement of the spleen may have no symptoms, but with moderate to severe splenomegaly, there will likely be some reduction in the number of circulating blood cells, abdominal pain, chest pain, early fullness, increased workload on the liver. ...Read more

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Is frequent hiccups sign of spleen enlargement. What is considered frequent? Toddler gets hiccups a lot

Is frequent hiccups sign of spleen enlargement. What is considered frequent? Toddler gets hiccups a lot

Common in toddlers: Toddlers and babies have immature brains. They are prone to having hiccups more than older children and adults. You can have the doctor check for any other causes, but it is likely normal. I have never seen hiccups from an enlarged spleen. I think theoretically it could irritate the diaphragm and cause them though. ...Read more

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My WBC and PLATELETS are reduce because of my spleen enlargement .....is this possible to cure this ?

My  WBC and PLATELETS are reduce because of my spleen enlargement .....is this possible to cure this ?

Need more info: Why is the spleen enlarged? The cause of splenic enlargement may be treatable. Common treatable causes in India are malaria and kala azar. It would be prudent to see a doctor for evaluation and choice of treatment. ...Read more

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I have too much extra copper in my body. Because of that my liver and spleen are large. What are my options.....?

I have too much extra copper in my body. Because of that my liver and spleen are large. What are my options.....?

Wilson's disease: There are chelating therapy available.....being young....your chances are better..... oral penicillamine with pyridoxine,indefinitely. Alternately, trientine. oral zinc interferes with copper absorption in gut. It is an autosomal recessive, watch with whom you shire a child....... ...Read more

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