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Doctor insights on: Causes Of Spastic Paraparesis

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What is tropical spastic paraparesis?

What is tropical spastic paraparesis?

Disorder of sp cord: A subacute condition with impairment of lower extremity >upper extremity function, sensory abnormalities, bladder functioning and girdling lumbar pain. About 80 % of patients with tsp have antibodies to htlv-1 (not aids virus..Htlv-3) the disorder and similar disorders were described in caribbean patients. ...Read more

Dr. Dariush Saghafi
5 doctors shared insights

Partial Paralysis Of Lower Limbs (Definition)

Paraparesis is a clinical finding in which an individual has weakness or spasticity (rigidity) of the lower ...Read more


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What is hereditary spastic paraparesis?

Rare condition: Progressive leg weakness and spasticity (tightness and catching of leg with flexion), caused by autosomal dominant and recessive or x-linked genetics, with usual slow progression and normal life span. Mri may demonstrate atrophy of brain and/or spinal cord. ...Read more

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What can I do about my hereditary spastic paraparesis?

What can I do about my hereditary spastic paraparesis?

Treat the symptoms: If the process is stable, and not progressing, best to try anti-spasticity meds, such as baclofen, tizanidine, or even a pump. Botox injections, although off-label, might be useful. Acupuncture has promise. Splints, braces, exercises all may help. If legal in your state, medical marijuana may help, as the research from europe suggests benefit in the spasticity associated with ms. ...Read more

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What is the definition of hereditary spastic paraparesis?

What is the definition of hereditary spastic paraparesis?

Hereditary SP: Hsp, is a genetic disorder transmitted as autosomal dominant, meaning one of the parent has the disease in order to pass it to the offspring. It is a progressive spasticity in the legs , may be associated with hypertonic urinary incontinence, seizure, dementia, or peripheral neuropathy. ...Read more

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Any treatment for heriditary spastic paraparesis? Accompanied by sensory neuropathy?

Any treatment for heriditary spastic  paraparesis? Accompanied by sensory neuropathy?

Symptomatic treatmen: Hsp is a group of inherited disorders, often insidiously progressive and severe. There are no effective treatments to the underlying damage to the nerve axons so treatment is symptomatic. Baclofen, dantrolene and tinazidine may help with spasticity; oxybutinin with urinary urgency; gabapentin, Pregabalin and duloxetine for neuropathy. Vitamins, d, e and b6 may also help. Physical therapy also. ...Read more

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Paraparisis cause? Its also known as familiar spastic paraplegia?

Paraparisis cause? Its also known as familiar spastic paraplegia?

See below: Paraparesis is a milder form of paraplegia ( which should mean no movement in the lower extremities but is sometimes used synonymously) familial spastic paraplegia is a paraplegia with family history of unknown etiology and is diagnosed when all the other causes have been ruled out. ...Read more

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What are the causes of spastic quadriplegia?

What are the causes of spastic quadriplegia?

Cerebral palsy: Quadreplegic cerebral palsy is the most common type, it is a static brain injury due to a sigifican injury to the brain like hypoxia and trauma, the most common cause in early life is hypoxic ischemic encephalopathy which occurred pernatally, around the time of delivery, exam showed increased muscle tone and brisk reflexes also with microcephaly and developmental delay. ...Read more

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What is the cause of spasticity in paralysis?

What is the cause of spasticity in paralysis?

Different theories: There are many different theories about what causes spasticity but the best explanation that i can give you is that under normal circumstances there is a balance between excitation and inhibition of muscle tone and movement. When there is injury or disease of the central nervous system (brain and spinal cord), there is excess excitation and not enough inhibition and the tone of certain muscles. ...Read more

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What can cause spastic paralysis on the right side of the body?

What can cause spastic paralysis on the right side of the body?

Anatomy: Causes include focal lesions of brain and spinal cord, and some underlying problems could include trauma, stroke, multiple sclerosis, infections, even primary lateral sclerosis. ...Read more

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What could cause spastic paralysis on the right side of the body?

What could cause spastic paralysis on the right side of the body?

Central lesion: Brain injury from trauma, bleed, tumor, aneurism, ischemia, infection, or spinal cord injury from similar mechanisms all can cause an upper motor lesion resulting in both paralysis and spasticity simultaneously. ...Read more