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Doctor insights on: Causes Of Signet Ring Cell Carcinoma

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Which Chemo drugs for gastric cancer stage iiB with signet ring cell (SRC) after surgery is/are better with less side effect and easier to purchase?

Which Chemo drugs for gastric cancer stage iiB with signet ring cell (SRC) after surgery is/are better with less side effect and easier to purchase?

Several useful drugs: You should be consulting your oncologist to explain what your cancer means in terms of its prognosis and what options of treatment he/she offers you. We have 4- chemo drugs that can be used. The one commonly used is Cisplatin often in combination with either 5-FU or Capecitabine(Xeloda). But there are several variations of chemo which have been tested and found useful. ...Read more

Dr. Barry Rosen
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Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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What does "metastatic signet ring cell adenocarcinoma" mean?

What does "metastatic signet ring cell adenocarcinoma" mean?

Several things.: In this sentence metastatic most likely means the disease has spread to other organs such as liver, lung, etc. And would be considered stage 4; alternatively it could mean spread to lymph nodes only and would represent stage 3 disease. Signet ring is a description of what the cell looks like. Adenocarcinoma is the type of tumor and can arise from the GI tract, prostate, lung, breast or stomach. ...Read more

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How long does it take for a stage 1 gastric signet ring cell tumor to grow into a stage 4?

How long does it take for a stage 1 gastric signet ring cell tumor to grow into a stage 4?

No one knows: Cancer is staged when it is discovered. You may have a cure. Or there may be cells hiding elsewhere, as in the liver, that will grow into metastases in a month, or five years from now. "stage" is a most-optimistic-possible-scenario assigned by the physician to guide treatment. I wish you luck and appreciate your proactive approach. ...Read more

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My father has a small tumor (signet ring cell) a little above the GE. He has gone through NA Chemo Radiation. What care shld we take b4 surgery?

My father has a small tumor (signet ring cell) a little above the GE. He has gone through NA Chemo Radiation. What care shld we take b4 surgery?

Make sure it has not: Check and make sure the tumor has not spread elsewhere before surgery is carried out. Surgery is only useful if the tumor is localized to one area and can be completely removed, leaving no visible or micscroscopic cancer cells behind. ...Read more

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If a large fungating signet ring cell mass is discovered in the gastric antrum blocking the pyloric canal in a 24-year-old female. Stage IV with metastasis to omentum. Was it was there 1 year earlier?

If a large fungating signet ring cell mass is discovered in the gastric antrum blocking the pyloric canal in a 24-year-old female. Stage IV with metastasis to omentum. Was it was there 1 year earlier?

Signet cell cancer: Stomach cancer with signet ring cell features on pathology is an aggressive and fast growing cancer which by virtue of omental/mesenteric or peritoneal involvement becomes stage 4 disease. I think this tumor probably grew in few months and not more than a year. Without treatment most patients only survive few months. ...Read more

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What causes squarmis cell carcinoma?

What causes squarmis cell carcinoma?

Depends on location: The most common form of squamous cell carcinoma (scc) occurs on skin, with sun damage being the leading cause. Scc can also occur in the esophagus, lung, oral cavity, and anal canal. Prolonged exposure to irritants such as smoking and chewing tobacco can lead to increased risk of scc in the lung and oral cavity. A certain type of virus (human papillomavirus) can also increase the risk of scc. ...Read more

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How frequently does basal cell carcinoma cause death?

How frequently does basal cell carcinoma cause death?

Almost never: I have seen this one time in 26 years of practice, and that was in a "street person" who had neglected the bcca on his face so long that it had grown into the brain. Otherwise the chances of this tumor causing death are tiny. ...Read more

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What does basal cell carcinoma feel like? My father has basal cell carcinoma and he constantly assures us that it doesn’t hurt. Does basal cell carcinoma cause any pain? .

What does basal cell carcinoma feel like? My father has basal cell carcinoma and he constantly assures us that it doesn’t hurt.  Does basal cell carcinoma cause any pain?

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Usually not painful: Usually no unless it ulcerates. It is a localized skin cancer (rarely spreads) and most times can be addressed fairly easily by a plastic surgeon with excision and local flap reconstruction. Take him to a specilaist so that it can be addressed while the lesion is small. ...Read more

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