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Doctor insights on: Causes Of Refractory Anemia

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Causes of aniocytosis?

Causes of aniocytosis?

Anisocytosis, having: Red blood cells (rbc's) of different sizes, can be caused by iron deficiency & sickle cell anemias, folate (folic acid) or vitamin B12 deficiency, autoimmune hemolytic anemia, cytotoxic chemotherapy, chronic liver disease, myelodysplastic syndrome, thalassemia major, & thalassemia intermedia. The unequal-sized rbc's are small in some of these disorders & large in others. ...Read more

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Dr. Steven Ginsberg
1,283 doctors shared insights

Anemia (Definition)

Any condition where there is a decrease in the red blood ...Read more


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What are the causes of pernicious anemia?

What are the causes of pernicious anemia?

Autoimmune disease: Pernicious anemia is an autoimmune disease producing autoantibodies against intrinsic factor found in the lining of the stomach. This leads to lack of absorption of vitamin B12 which is important in making blood cells and for nourishment of the nervous system. Treatment would be by replacement of B12 via injections or absorption into the body by other means (nasal spray). ...Read more

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Which kind of blood cancer cause idiopathic thrombocytopenia ? Including chronic malignancy

Which kind of blood cancer cause idiopathic thrombocytopenia ? Including chronic  malignancy

By itself: Essential thrombocythemia is a low-grade blood cancer that often requires no treatment. Most unexplained thrombocytosis in people who seem well otherwise is due to iron deficiency. Nobody understands how this works. Hoping you find the answers you need, and glad you asked. ...Read more

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Which type of anemia can cause fatigue?

Which type of anemia can cause fatigue?

Anemia: Anemia can be mild, moderate and severe depending upon the hemoglobin or hematocrit measure! as severity of anemia increases, it is proportional to the fatigue one experiences! usually anemia as a result of blood loss or hemolytic anemia or B12 deficiency causes more fatigue. Other causes such as anemia of chronic disease is mild and relatively asymptomatic or compensated. ...Read more

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Causes of hypergammaglobulinemia?

Causes of hypergammaglobulinemia?

Mono or Polyclonal: High levels of immunoglobulins (hypergammaglobulinemia) can be monoclonal (specific) - due to malignant proliferation of plasma cells or lymphocytes as in myeloma or waldenstrom's macroglobulinemia. Polyclonal (many types) hypergammaglobulinemia is a benign condition due to infection, inflammation causing non-specific gamma globulin production such as in hepatitis, immune and allergic disorders. ...Read more

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What is refractory anemia with excess of blasts?

What is refractory anemia with excess of blasts?

A type of MDS: Refractory anemia with excess blasts is a type of myelodysplastic syndrome (MDS). The bone marrow will have between 5-19% blasts per high powered microscope field. This illness is a "preleukemia" or an evolving leukemia. Progression to leukemia can happen in 12 months, and many patients will require transfusions for low blood counts. Treatments can prevent progression to leukemia. ...Read more

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Why is iron deficiency anemia different from the other types of anemia?

Why is iron deficiency anemia different from the other types of anemia?

Iron deficiency: There are many types of anemia caused by many types of disorders. Red blood cells require iron in order to develop properly. Without iron, we do not produce adequate numbers of cells which results in anemia. Iron deficiency needs to be explained always and requires an examination and further testing. Simply replacing iron without an investigation and or examination can result in missed diseases. ...Read more

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What are causes of normocytic hyperchromic anemia?

Hemolytic anemia: Anemia can be due to many factors and to even begin to know, clues are found on the size(normo, macro, micro) and coloration (hypo(pale color), normochromic(normal red color). When red cells lack a normal center, as in spherical forms, " hyperchromic" is used loosely, though the correct term may be spherocytes. Hemolytic anemia, with many causes, lead to normochromic "hyperchromic"anemia. ...Read more

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What are the causes of macrocytic hypochromic anemia?

What are the causes of macrocytic hypochromic anemia?

See below: Macrocytic anemia has several causes. Most common causes are vitamins B12 and folate (folic acid) deficiency, liver disease, alcohol excess. There are other less common causes. ...Read more

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How to determine underlying causes of recurring anemia or deficiency of haemoglobin?

Blood & stool tests: Additional blood testing can help direct cause of anemia / hemoglobinopathies. Menstrual history and physical exam w/fecal occult blood test (=test stool for blood) to determine if excess losses via menses or in stool. See dr. ...Read more

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Causes of low anemia in men?

Low Blood Count: This is a rare situation for younger men. So, it must be taken seriously. First would be a general sense of one's health. Are there any chronic illnesses or infections? Next would be if there could be a bleeding ulcer or other situation in the GI tract. Any good medical provider will investigate this situation fully to make sure the cause is identified and treated. ...Read more

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What are the causes of symptoms in pernicious anemia?

What are the causes of symptoms in pernicious anemia?

Lack of vitamin B12: Pernicious anemia is due to a lack of vitamin b12. B12 is necessary for the normal function of the nervous system and the formation of red blood cells. ...Read more

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What cause the symptoms of sickle cell anemia?

What cause the symptoms of sickle cell anemia?

Symptoms of SS: The altered shape of the red blood cells causes them to stack up together and clog blood vessels, depriving the tissues of adequate blood supply and oxygen. The tissues then die (infarct) and this causes pain. The red cells also rupture or are eaten by the spleen and cause anemia. The spleen itself will gradually infarct, leaving the patient susceptible to infections. ...Read more

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Which causes iron deficiency anaemia to be different to other types of anaemia?

Which causes iron deficiency anaemia to be different to other types of anaemia?

Types of anemia: There are many causes of anemia. Anemia means a low blood count which can be caused by inadequate production of red blood cells in the bone marrow or excessive loss of blood from different sites in the body. Two of the most common are the uterus and the bowel. Anemia is a sign of a problem which requires diagnosing the cause. Iron deficiency is one such cause. ...Read more

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Why there is pancytopenia in anemia of b12 and folic acid deficiency??

Why there is pancytopenia in anemia of b12 and folic acid deficiency??

Cell maturation: B12 and folic acid are need for DNA synthesis and maturation of all cells. The cells affected are not only red cells, white cell, and platelets but almost all cells in the body, including brain and spinal cord cells. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. Get HPV vaccine. ...Read more

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Is anemia from B12 deficiency a life-threatening condition?

Is anemia from B12 deficiency a life-threatening condition?

Not if treated: It takes a very long time for you to get near death from B12 deficiency. The treatment is so simple and effective, why chance it? ...Read more

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Can hypothyroidism be the cause of microcytic hypochromic anemia?

Can hypothyroidism be the cause of microcytic hypochromic anemia?

Not usually: Microcytic anemia is usually due to iron deficiency, rather than hypothyroidism. If associated with hypothyroidism, anemia is usually macrocytic (often secondary to pernicious anemia). Either way, an anemia deserves a thorough workup with your medical doctor, and treatment of your hypothyroidism. Best wishes! ...Read more

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