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Doctor insights on: Causes Of Positive Ana

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What causes positive ANA results?

What causes positive ANA results?

Possibly normal: Up to 5% of healthy people may have a low titer ana. Lupus and other autoimmune diseases and sarcoidosis are possiblities. Diagnosis is on the basis of associated findings, not the ANA by itself. ...Read more

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Ana (Definition)

An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood and looking at a number ...Read more


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What are the causes of a positive ANA test result?

What are the causes of a positive ANA test result?

Many: ANA can be positive in many diseases and in many apparently healthy people. By itself , it does not mean much other than pointing to a higher but not certain risk for an individual to develop an autoimmune disease. ...Read more

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What could a positive ANA of 1:640 speckled indicate if lupus and rheumatoid arthritis tests are negative?

What could a positive ANA of 1:640 speckled indicate if lupus and rheumatoid arthritis tests are negative?

Need more testing: ANA is a screening test. A positive result only indicates more testing might be needed. The speckled portion of the result is not very helpful on its own. About 5% of humans (1 in 20) have a positive ANA for no reason. ...Read more

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Can mold exposure cause a positive ANA of both speckled and nucleolar?

Can mold exposure cause a positive ANA of both speckled and nucleolar?

Not likely,,,,: The ANA is usually, if not always due to an autoimmune issue like lupus or rheumatoid arthritis, not infectious like mild or bacteria. You would likely have other symptoms of mold exposure like nasal stuffiness and some irritation. Good luck. ...Read more

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Could fibromalagia cause ANA positive? 1:640 speckled and sed rate elevated? Lupus panel negative

Could fibromalagia cause ANA positive?  1:640 speckled and sed rate elevated? Lupus panel negative

NO: The ANA is there because of some other reason. Because it's there does not mean you have lupus. There are many other reasons to have a positive ana. Your evaluation by your physician can clarify. ...Read more

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What are causes of false positive drug tests?

Positive drug tests: You have taken something that shows up with the test used. Discuss with your tester as there are many different tests. ...Read more

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ANA 1:320 Homogenous pattern, positive ssDNA, and chromatin antibodies 60 u/ml. Fatigue and joint pain. Is lupus a possibility?

ANA 1:320 Homogenous pattern, positive ssDNA, and chromatin antibodies 60 u/ml. Fatigue and joint pain. Is lupus a possibility?

Yes: 1:320 along with positive ssDNA Ab and the symptoms you are having makes Systemic Lupus a strong possibility. I suggest seeing a Rheumatologist so they can also evaluate and potentially initiate treatments. ...Read more

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I've had a strong positive ANA test result. All the various antibody tests are negative.. Symptoms are, joinfpain fatigue hive episode, fevers, etc. ?

Close but not there: Doesn't sound like you have a rheumatologic illness yet. You may develop one. If your ANA was positive at greater than 1:640 you should be monitored every six months for progression of symptoms if not you should be monitored less often. ...Read more

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Causes of elevated CRP (18.4) and C4 comlement (46)? History: ana, ccp positive. Sjogren's symptoms but ssa/b neg. No arthritis. Fatigued.?

Causes of elevated CRP (18.4) and C4 comlement (46)? History: ana, ccp positive. Sjogren's symptoms but ssa/b neg. No arthritis. Fatigued.?

You have inflammatio: Your tests indicate inflammation. Sjogren's not associated with high inflammation. Ccp positivity fairly specific for ra. Chronic fatigue is common in both RA and sjogrens. And sjogren's (2') common in ra! responds well to Nuvigil or provigil! have you seen a rheumatology specialist to sort things out? ...Read more

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Positive ANA with titer 1:80 Homogeneous AND 1:80 Speckled. What does this all mean? Constant headaches and fatigue. Possibility of Lupus?

May be: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, ANA positive at 1:80 is just above the normal limit and may not mean any disease. It would be prudent to consult a rheumatologist. For info http://www.rheumatology.org/practice/clinical/patients/diseases_and_conditions/ana.asp ...Read more

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I'm having negative DNA ,Sm and Rnp antibodies, but positive sm/rnp antibody,and high ANA titre speckled,so what is the diagnosis ?

Lupus: These serologies are rather non specific. The speckled ANA is non specific. In Systemic Lupus Erythematosis (SLE) it is usually homogeneous in its staining. Anti-Sm and Anti RNP can be see in mixed connective-tissue diseases and overlaps with SLE, scleroderma and myositis. As often is the case a specific diagnosis cannot be made. You need to see a Rheumatologist. ...Read more

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What causes false positive ALT result?

No such thing: If the alt is elevated, something's caused the enzyme to leak from your liver and/or skeletal muscles. Today's assays are reliable. But this does not necessarily means you are sick. It can be from the ultramarathon you just ran, or the Ibuprofen you took for the cold you're now better from. Your physician knows how to follow this up -- often just a repeat draw will lay concerns to rest. ...Read more

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I have a lab result of positive ANA screen, ifa. Ana pattern is speckled and ANA tilter is 104H. Is this of concern. Have fingers and toes draw up.

I have a lab result of positive ANA screen, ifa.  Ana pattern is speckled and ANA tilter is 104H. Is this of concern.  Have fingers and toes draw up.

Big picture: About one grown woman in four has detectable antinuclear antibodies. They are only on part of the workup for your back pain / fatigue. For most people, they are of no consequence. They are of course the basic screening test for lupus and for a few other illnesses, but you're not a lupus patient yet. Best wishes -- stay proactive and keep asking these good questions. ...Read more

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Would a negative ANA rule out lymphoma? Does lymphoma cause a positive ANA test result?

It does not: At your age, if you have lymphoma it's probably Hodgkin's. ANA really has nothing to do with malignant lymphoma. If you're worried about big lymph nodest, trust me -- lymphoma nodes are obviously very abnormal. Best wishes, and I hope you'll always stay actively involved with your health. ...Read more

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Lab tests showed the following: ANA w/titre & pattern 1:320 and a thyroid peroxidase ab 484.0...Could high ANA be because of positive hashimoto's?

No: Hoshimoto's is an autoimmune disease. ANA is elevated in autoimmune diseases. Hoshimoto's doesn't cause the elevated ANA but an autoimmune state causes both the elevated ANA and thyroid antibodies which cause hoshimoto's. ...Read more