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Doctor insights on: Causes Of Polychromasia

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Polychromasia & anisocytosis--are they bad?

Polychromasia & anisocytosis--are they bad?

If both are: Reported that would indicate a blood smear with size and color variation in the red blood cells. While a potential sign of a "stressed" marrow, it would be an over call to say this in and of itself is "bad.". ...Read more

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Dr said Rbc morphology my 5yo is normal but when I got the report it said spherocytes and polychromasia is 3-5/hpf. Concern?

Dr said Rbc morphology my 5yo is normal but when I got the report it said spherocytes and polychromasia is 3-5/hpf. Concern?

Discuss With Doctor: Spherocytes are seen in certain types of anemia; most frequent being Hereditary Spherocytosis, a genetic disorder. Polychromasia refers to presence of Reticulocytes and indicates premature RBC destruction. Other tests are usually performed with these results and this important info is not given. Discuss these findings with doctor and any other testing done to confirm if further concern warranted. ...Read more

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I have idiopathic waiha IgG latest tests show both spherocytes, red cell fragments and mild polychromasia.. what is going on please?

I have idiopathic waiha IgG latest tests show both spherocytes, red cell fragments and mild polychromasia.. what is going on please?

Is a rare disease.: Autoimmune hemolytic anemia. An autoimmune disorder occurs when the body's immune system attacks and destroys healthy body tissue by mistake, in this case your red cells. When the red cells are coated with IgG or IgG plus C3d, the antibody is usually a warm antibody (warm antibody AIHA [WAIHA]). You need to be closely monitored by an expert hematologist, given the seriousness of this condition. ...Read more

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Why is there polychromasia in sickle cell?

Young red cells: In sickle cell disease, young red blood cells are released from the bone marrow since the rate of turnover of the older blood cells is quicker. Your body is trying to produce more red blood cells to keep up with the destruction that occurs in sickle cell disease. Polychromasia means early release of red blood cells. ...Read more

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What does it mean for a blood smear to show moderate polychromasia and moderate Schistocytes? Google doesn't give a good picture. :) Thanks

What does it mean for a blood smear to show moderate polychromasia and moderate Schistocytes?  Google doesn't give a good picture.   :)  Thanks

Worrisome: Look for something fragmenting the red blood cells. If the person isn't obviously sick with disseminated intravascular coagulation or thrombotic thrombocytopenic purpura, perhaps they have an old-fashioned mechanical heart valve. Polychromasia should prompt a search for causes of hemolysis. The pathologist may want to review this slide. Best wishes. ...Read more

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Is it normal for a 2.5 YO to have results of Anisocytosis: Rare Burr Cells: Slight, Microcytes: Rare, Polychromasia: Rare on a morphology Report?


Is it normal for a 2.5 YO to have results of Anisocytosis: Rare Burr Cells: Slight, Microcytes: Rare, Polychromasia: Rare on a morphology Report?

2.5 YO: No, your comments are not "normal". If your child has the issues you report you must continue to see a specialist. If you are not satisfied with the doctor you take tour child, have one of your friends refer you to a doctor with whom you will be more satisfied. Wish the baby well - please keep me posted; we can all learn something. ...Read more

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Hi, my manual diff came back with Poikilocytosis 1+ Polychromasia 1+ Ovalocytes 1+ Tear Drop Cells 1+ Spherocyte 1+. Monocytosis No picture available. Is this unusual?

Hi, my manual diff came back with Poikilocytosis 1+ Polychromasia 1+ Ovalocytes 1+ Tear Drop Cells 1+ Spherocyte 1+. Monocytosis No picture available. Is this unusual?

No: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, there is nothing of concern in the information you provided. It would have helped to know rest of the data, esp Hemoglobin and WBC, ...Read more

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My 58 year old husband has a WBC of 34.5 hh, lymph 83 h no significant poikilocytosis or polychromasia mdm. Is this cll?

My 58 year old husband has a WBC of 34.5 hh, lymph 83 h no significant poikilocytosis or polychromasia mdm. Is this cll?

Sounds like it: Obviously the WBC and the absolute lymphs are both significantly elevated. Cll is by far the most likley diagnosis. ...Read more

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Is polychromasia typically associated with microcytic anemia (iron deficient anemia)?

Is polychromasia typically associated with microcytic  anemia (iron deficient anemia)?

Iron deficiency is: Usually hypo chromic. Polychromasia is seen in rapidly changing circumstances like hemolytic anemia. ...Read more