Doctor insights on:
Causes Of Pleomorphic Adenoma
Hi. I need help. Will you please tell me or explain to me the pathophysiology of pleomorphic adenoma? Thanks
Little to it: The anatomic pathology of pleomorphic adenoma is amazingly complex, and we are learning a bit about its molecular biology. The lesions are benign but locally destructive, especially endangering the facial nerve if in the parotid. Wide excision is required as the lesion sends out projections. Around 1% is the site of origin for a real cancer. ...Read more
We use the term pleomorphic often in pathology; it literally means "many shapes". Pleomorphic cells in a tumor may tell of the genetic instability that's central to cancer, but the benign pleomorphic adenoma of the salivary glands merely has many different tissue types. The ...Read more
Primary tx: Superficial parotidectomy is the treatment of choice for most benign tumors in the superficial lobe. ...Read more
I ve 1.8cm *1.3cm pleomorphic adenoma on superficial lobe of patotid gland. Scared to do surgery. Possible complications of surgery? Postoperative care?
I am suffering from pleomorphic adenoma I.e benign tumour of partoid gland. I have already undergone for parotidectomy for three times. What can I do?
Medical School: See the best head and neck (ENT) surgeon at the closest University Medical Center near you. ...Read more
If you had a benign pleomorphic adenoma in a minor salivary gland for approx 5 years would you have it surgically removed?
Could my son get cancer if he was diagnosed with pleomorphic adenoma, 3 tumors in the neck and 1 in cheek?
Rarely: Pleiomorphic adenomas are benign tumors of saliva glands. It is unusual for them to be in the neck itself, but they can arise "rests" of salivary tissue in the neck. They tend not to spread to other parts of the body but can grow back in the areas where they arose in about 20% of patients who had surgery. Rarely they can turn cancerous and spread to other organs. Best wishes. ...Read more
My son was diagnosed with pleomorphic adenoma, 3 tumors in the neck and 1 in cheek. Could this become cancer?
My mum was diagnosed with pleomorphic parotid adenoma and she has a heart condition. Is an operation really necessary? My mum is 79
What do you suggest if my son was diagnosed with pleomorphic adenoma, 3 tumors in the neck and 1 in cheek. Can this turn into cancer?
Early ENTinvolvement: Close follow-up with the ENT, surgical resection is required. Yes, these have a high rate of malignant transformation. ...Read more
I have had surgery twice of the parotid gland (pleomorphic adenoma). Now from last 1 month my intra parotid lymph nodes are swollen, why?
Many possible reason: If you are certain this is an intraparotid lymph node (as opposed to a nodule of recurrence of pleomorphic adenoma), there could be many possible causes ranging from some infection, to inflammatory diseases either specific to the parotid or more general, to some other tumor. The person who did your most recent parotid surgery is probably in the best position to answer this question. ...Read more
What is the likelihood of a repeat pleomorphic adenoma causing damage to the mandibular nerve when the tumor is located low internally in the right neck/jaw and close to the jugular. The child had her first removed in 2009 when she was 9, she is no
Will hole in roof of mouth to sinus area from pleomorphic adenoma removal heal closed or will I require another surgery?
Few days ago I have left parotid pleomorphic adenoma Specimen Type left superfacial parotid gland but after surgery I have salivary leakage probl?
Fistula: It sounds like you have a salivary fistula which is a rare complication of partial parotidectomy. Usually will close spontaneously in a few weeks and very rarely persists for months or chronically. However, since you are "fresh post-op"only a few days after surgery, PLEASE call the surgeon and make sure s/he sees you. Get well soon ...Read more
Small pleomorphic adenoma (<2cm) on postero inferior part of superficial parotid gland. Traditional incision needed? Anyone do micro parotidectomy in ct?
Traditional incision: Pleomorphic adenoma of the superficial lobe of parotid requires removal of the superficial lobe. This operation is not performed on the lobe per se but on identifying the facial nerve and its branches and lifting the lobe off the nerve. The incision is designed to give landmarks that define the trunk of the nerve as it comes out of the stylomastoid foramen. Procedure this way is under 1 hr. ...Read more
Many shapes: We use the term pleomorphic often in pathology; it literally means "many shapes". Pleomorphic cells in a tumor may tell of the genetic instability that's central to cancer, but the benign pleomorphic adenoma of the salivary glands merely has many different tissue types. The context gives the meaning. ...Read more
Generally Benign: This is a neoplasm of the brain that generally affects children and teenagers. They are considered generally benign and are classified as grade 2 astrocytomas. They develop from astrocytes which are cells of our brains. They are usually slow growing and often present with sudden onset of seizures due to pressure in the brain. Very rarely do these tumors undergo malignant transformation. ...Read more
My diag mammo stated presence of a small tightly grouped microcalcifications slightly pleomorphic and represent interval how serious? Going to see BS
Be concerned!: By your description a biopsy would be indicated. This can be performed with ultrasound guidance if there are findings by u/s in the region, or if not, with stereotactic guidance. These can easily be performed by a radiologist skilled in these procedures, or by a breast surgeon. This should be done as soon as possible. ...Read more
What is gram negative pleomorphic bacilli? My sputum culture is growing this out. Beta lactamase negative. Been sick 1 month 3 abx tx and steroids x3
Needs biopsy: Suspicious cluster opleomorphic microcalcifications on mgram may be due to breast cancer. Therefore you need to undergo a biopsy. Usually they sggest a stereotactic biopsy which is a type od percutaneous needle biopsy n a special x-ray table. Please follow with a breast carer specialist or a radiologist experien in this procedure. ...Read more
Had mgram which showed pleomorphic calcs in r breast. Have biopsy in monday. What is rate of cancer assoc with this type? Can they be benign too?
Probably benign: There's about a 12% risk these will prove to be malignant. That leaves an 88% chance of benignancy. Good luck with the biopsy - I hope you get good results. ...Read more
Internet info states that if breast calc are defined pleomorphic that risk of being malignant goes way up to 1 in 4. Is this true? Have biopsy mon
Relax: Relax until you get your results. Then, have the doctor explain until you understand - or have a close person along to also get the info. Before results there is nothing you can do - so try to stay calm. Afterwards ask for a referral to a supportive therapist to help you through the treatment choices. It can make a big difference in your outcome and adjustment. I hope it goes well for you. ...Read more
Is there any connection between a swollen lymph node in the breast and clustered pleomorphic microcalcifications?
Needs investigation: Although breast calcifications may not necessarily mean cancer, pleomorphic calcifications are suspicious. A biopsy should be done. Talk to your doctor. Pleomorphism means that something is of varying shape and characteristics. A non-cancerous or benign calcification will be read as "benign-appearing". Don't delay your biopsy. ...Read more
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